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pro vyhledávání: '"resident cells"'
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Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
We previously demonstrated that brain-resident cells produce IFN-γ in response to reactivation of cerebral infection with Toxoplasma gondii. To obtain an overall landscape view of the effects of IFN-γ from brain-resident cells on the cerebral prote
Externí odkaz:
https://doaj.org/article/976c59eadae64f6d8326aacdabdb4123
Autor:
Polly Matzinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
For decades, the main question immunologists have asked about autoimmunity is “what causes a break in self-tolerance?” We have not found good answers to that question, and I believe we are still so ignorant because it’s the wrong question. Rath
Externí odkaz:
https://doaj.org/article/21efb28d91df4dec8f8c0d0a482fc458
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
The skin is the outermost barrier of the body. It has developed a sophisticated system against the ever-changing environment. The application of single-cell technologies has revolutionized dermatology research and unraveled the changes and interactio
Externí odkaz:
https://doaj.org/article/c4a112a56b3f481886bb4eea6fa0ac28
Autor:
Samuel Kemble, Adam P. Croft
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rheumatoid arthritis (RA) is a chronic prototypic immune-mediated inflammatory disease which is characterized by persistent synovial inflammation, leading to progressive joint destruction. Whilst the introduction of targeted biological drugs has led
Externí odkaz:
https://doaj.org/article/a07ef7cd7de94f499f85a58df7f82ae4
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lupus nephritis (LN) is a common complication of systemic lupus erythematosus (SLE) and a major risk factor for morbidity and mortality. The abundant cell-free nucleic (DNA/RNA) in SLE patients, especially dsDNA, is a key substance in the pathogenesi
Externí odkaz:
https://doaj.org/article/ce30f1646cdb44b3a66c72cb26a86059
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Mucosal-associated invariant T (MAIT) cells are innate-like T cells present at considerable frequencies in human blood and barrier tissues, armed with an expanding array of effector functions in response to homeostatic perturbations. Analogous to oth
Externí odkaz:
https://doaj.org/article/d8b729c994f44eec88696026a57daf08
Autor:
Iva Filipovic, Isabella Sönnerborg, Benedikt Strunz, Danielle Friberg, Martin Cornillet, Laura Hertwig, Martin A. Ivarsson, Niklas K. Björkström
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Recent studies have demonstrated extraordinary diversity in peripheral blood human natural killer (NK) cells and have suggested environmental control of receptor expression patterns on distinct subsets of NK cells. However, tissue localization may in
Externí odkaz:
https://doaj.org/article/7672e4312e944a8bad0cece9de2e1c56
Autor:
Špela Konjar, Marc Veldhoen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
In the past years, there have been significant advances in the understanding of how environmental conditions alone or in conjunction with pathogen invasion affect the metabolism of T cells, thereby influencing their activation, differentiation, and l
Externí odkaz:
https://doaj.org/article/049b4d7be1754474945271a4ac65213b
Autor:
Clara Degos, Mellie Heinemann, Julien Barrou, Nicolas Boucherit, Eric Lambaudie, Ariel Savina, Laurent Gorvel, Daniel Olive
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Endometrial Cancer is the most common cancer in the female genital tract in developed countries, and with its increasing incidence due to risk factors such as aging and obesity tends to become a public health issue. However, its immune environment ha
Externí odkaz:
https://doaj.org/article/77a7859e64e74b959a642ba9dc002a7c