Zobrazeno 1 - 10
of 368
pro vyhledávání: '"replicative stress"'
Autor:
Angélique Bruyer, Laure Dutrieux, Hugues de Boussac, Thibaut Martin, Djamila Chemlal, Nicolas Robert, Guilhem Requirand, Guillaume Cartron, Laure Vincent, Charles Herbaux, Malik Lutzmann, Caroline Bret, Philippe Pasero, Jérôme Moreaux, Sara Ovejero
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Multiple myeloma (MM) is a hematological malignancy characterized by an abnormal clonal proliferation of malignant plasma cells. Despite the introduction of novel agents that have significantly improved clinical outcome, most patients relapse and dev
Externí odkaz:
https://doaj.org/article/5f646fda97b9447783fcecabae90b4cd
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 2, Pp 151331- (2023)
Mesenchymal stem cells (MSCs) have emerged as promising cell-based therapies in the treatment of degenerative and inflammatory conditions. However, despite accumulating evidence of the breadth of MSC functional potency, their broad clinical translati
Externí odkaz:
https://doaj.org/article/550bb6e4fa5a4f2f879b7a7d4cfc353a
Akademický článek
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Autor:
Su-Jung Kim, Chrystelle Maric, Lina-Marie Briu, Fabien Fauchereau, Giuseppe Baldacci, Michelle Debatisse, Stéphane Koundrioukoff, Jean-Charles Cadoret
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10629 (2023)
Over the last decade, CDK4/6 inhibitors (palbociclib, ribociclib and abemaciclib) have emerged as promising anticancer drugs. Numerous studies have demonstrated that CDK4/6 inhibitors efficiently block the pRb-E2F pathway and induce cell cycle arrest
Externí odkaz:
https://doaj.org/article/169aad9622d2469587cd89902f26678c
Autor:
Mengjia Qian, Xin Cao
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Lung large cell carcinoma is a common type of lung cancer with poor prognosis. Although targeted drugs have achieved enormous success in treating non‐small‐cell lung carcinoma (NSCLC), new chemotherapy is needed since the emerged drug re
Externí odkaz:
https://doaj.org/article/42503e46d09643328bf0f102ddc9e429
Autor:
Zeinaty, Alya
Le resvératrol (RV/RSV) est un composé chimique organique connu pour ses effets anticancéreux mais aussi pour son effet rajeunissant sur les cellules et les organismes. Afin d’étudier le ou les multiples mécanismes à l’origine de ces effets
Externí odkaz:
http://hdl.handle.net/1866/32850
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Glioblastoma multiforme (GBM) is a malignant tumor of the central nervous system (CNS). The poor prognosis of GBM due to resistance to therapy has been associated with high chromosomal instability (CIN). Replication stress is a major cause of CIN tha
Externí odkaz:
https://doaj.org/article/3bdd4ab05fd14c9dbf2e5a39d10664d1
Autor:
Mélanie K. Prodhomme, Sarah Péricart, Roxane M. Pommier, Anne-Pierre Morel, Anne-Cécile Brunac, Camille Franchet, Caroline Moyret-Lalle, Pierre Brousset, Alain Puisieux, Jean-Sébastien Hoffmann, Agnès Tissier
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Breast cancer cells frequently acquire mutations in faithful DNA repair genes, as exemplified by BRCA-deficiency. Moreover, overexpression of an inaccurate DNA repair pathway may also be at the origin of the genetic instability arising during the cou
Externí odkaz:
https://doaj.org/article/62d2634ad0974109888f7e46b74d8f22
Autor:
William Tremblay, Florence Mompart, Elisa Lopez, Muriel Quaranta, Valérie Bergoglio, Saleha Hashim, Delphine Bonnet, Laurent Alric, Emmanuel Mas, Didier Trouche, Julien Vignard, Audrey Ferrand, Gladys Mirey, Anne Fernandez-Vidal
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The cytolethal distending toxin (CDT) is produced by several Gram-negative pathogenic bacteria. In addition to inflammation, experimental evidences are in favor of a protumoral role of CDT-harboring bacteria such as Escherichia coli, Campylobacter je
Externí odkaz:
https://doaj.org/article/73b7f00b96bc45e4bd380d971c372e41
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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