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Repeated Evolution

Autor: Kassen, Rees, author

Publikováno v: Experimental Evolution and the Nature of Biodiversity, 2024, ill.

Externí odkaz: https://doi.org/10.1093/oso/9780192898661.003.0006

The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs)

Autor: Lingjie Zhang, Tong Deng, Zhongqi Liufu, Xueyu Liu, Bingjie Chen, Zheng Hu, Chenli Liu, Miles E Tracy, Xuemei Lu, Hai-Jun Wen, Chung-I Wu

Publikováno v: eLife, Vol 13 (2024)

Tumorigenesis, like most complex genetic traits, is driven by the joint actions of many mutations. At the nucleotide level, such mutations are cancer-driving nucleotides (CDNs). The full sets of CDNs are necessary, and perhaps even sufficient, for th

Externí odkaz: https://doaj.org/article/17c84fcf8253415d97b5a9761f06d7eb

The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs).

Autor: Zhang L; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China., Deng T; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China., Liufu Z; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; State Key Laboratory of Genetic Resources and Evolution/Yunnan Key Laboratory of Biodiversity Information, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, China., Liu X; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China., Chen B; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, China., Hu Z; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Liu C; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Tracy ME; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China., Lu X; State Key Laboratory of Genetic Resources and Evolution/Yunnan Key Laboratory of Biodiversity Information, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, China., Wen HJ; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; Innovation Center for Evolutionary Synthetic Biology, Sun Yat-sen University, Guangzhou, China., Wu CI; State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; Innovation Center for Evolutionary Synthetic Biology, Sun Yat-sen University, Guangzhou, China.; Department of Ecology and Evolution, University of Chicago, Chicago, United States.

Publikováno v: ELife [Elife] 2024 Dec 17; Vol. 13. Date of Electronic Publication: 2024 Dec 17.