Zobrazeno 1 - 10
of 1 279
pro vyhledávání: '"renal tubular epithelial cells"'
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Diabetic nephropathy (DN) is a common complication of diabetes mellitus, and Prolyl 4-Hydroxylase Subunit Beta (P4HB) expression is increased in high glucose (HG)-induced renal tubular epithelial cells (TECs). But it’s role in H
Externí odkaz:
https://doaj.org/article/fdad116fb2fd4af185ad8f2ae19ccc60
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to elucidate the influence of miR-483-3p on human renal tubular epithelial cells (HK-2) under high glucose conditions and to understand its mechanism. Human proximal tubular epithelial cells (HK-2) were exposed to 50 mmol/L
Externí odkaz:
https://doaj.org/article/1ce204b4d6144a1ea0df1b55d15c7cda
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Objective Contrast media (CM) is a commonly applied drug in medical examination and surgery. However, contrast-induced acute kidney injury (CIAKI) poses a severe threat to human life and health. Notably, the CUT-like homeobox 1 (CUX1) gene s
Externí odkaz:
https://doaj.org/article/8f37e7c6f051444a8157cdae9c8795ac
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105294- (2024)
Summary: Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid and significant decrease in renal function that can arise from various etiologies, and is associated with high morbidity and mortality. The renal tubular epithelial ce
Externí odkaz:
https://doaj.org/article/683251a8a21f4f71a04f00aa1870d743
Autor:
Yini Bao, Qiyuan Shan, Keda Lu, Qiao Yang, Ying Liang, Haodan Kuang, Lu Wang, Min Hao, Mengyun Peng, Shuosheng Zhang, Gang Cao
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 8, Pp 100933- (2024)
Renal fibrosis is a devastating consequence of progressive chronic kidney disease, representing a major public health challenge worldwide. The underlying mechanisms in the pathogenesis of renal fibrosis remain unclear, and effective treatments are st
Externí odkaz:
https://doaj.org/article/95aa8bed53b249a292967d01187c6a74
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116804- (2024)
Acute kidney injury (AKI) is associated with both kidney function loss and increased mortality. In the pathological progression of ischemia-reperfusion-induced AKI, the surge of reactive oxygen species (ROS) plays a crucial role. To combat this, mito
Externí odkaz:
https://doaj.org/article/b62fa6130f974a0b90eb12a506b4973f
Publikováno v:
Linchuang shenzangbing zazhi, Vol 24, Iss 3, Pp 238-243 (2024)
Due to various causes, chronic kidney disease(CKD) is characterized by chronic irreversible changes in the structure and function of kidney. The most common pathological manifestation is renal fibrosis. Many studies have demonstrated that injured
Externí odkaz:
https://doaj.org/article/70fc0db0c7a74afc9ecfb4e1b45c8498
Autor:
Qi Jin, Fang Ma, Tongtong Liu, Liping Yang, Huimin Mao, Yuyang Wang, Liang Peng, Ping Li, Yongli Zhan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Sirtuins, which are NAD+-dependent class III histone deacetylases, are involved in various biological processes, including DNA damage repair, immune inflammation, oxidative stress, mitochondrial homeostasis, autophagy, and apoptosis. Sirtuin
Externí odkaz:
https://doaj.org/article/dbc4789bbecd4e1893b6b020cce3209b
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 903-911 (2024)
Chenhao Xing,1 Yamin Lu,2 Guangxia Liu,2 Fang Chen,2 Zhan Hou,2 Yiwen Zhang2 1Graduate School of Hebei North University, Hebei North University, Zhangjiakou, Hebei, People’s Republic of China; 2Department of Nuclear Medicine, Hebei General Hospital
Externí odkaz:
https://doaj.org/article/d1cfebfa8ed84f2795cbba58d34783ef
Autor:
Shuhang Zhang, Yingqingqing Zhang, Hai Yin, Yiling Liu, Lihui Tang, Yanli Zhu, Pinzhi Sun, Kexin Wu, Baoyu Zhao, Hao Lu
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Locoweed is a poisonous plant widely present in grasslands around the world. Swainsonine (SW), an indole alkaloid that, is the main toxic component of the locoweed. To understand the mechanism of SW-induced toxicity and to delineate the metabolic pro
Externí odkaz:
https://doaj.org/article/e3353cadd4d54b8999bbeec39a3ee023