Zobrazeno 1 - 10
of 1 544
pro vyhledávání: '"renal interstitial fibrosis"'
Publikováno v:
Guoji laonian yixue zazhi, Vol 45, Iss 4, Pp 490-494 (2024)
Renal interstitial fibrosis (RIF) is a crucial and irreversible element that speeds up the advancement of diabetic nephropathy (DN) to end-stage renal disease. DN-RIF, which is mostly caused by long-lasting inflammation, is greatly affected by the NO
Externí odkaz:
https://doaj.org/article/41af3f9aed91442cba210f08b63900c9
Autor:
Yong-hong Jian, Yi-fei Yang, Xue-yan Yang, Ling-li Cheng, Yu-han Wan, Qian Guan, Ding-ping Yang
Publikováno v:
Linchuang shenzangbing zazhi, Vol 24, Iss 7, Pp 579-587 (2024)
Objective To observe the expression of silent information regulator 3 （Sirt3）, detect the level of aerobic glycolysis in renal fibrosis model and explore the role of Sirt3 in renal interstitial fibrosis. Methods Wild-type and Sirt3 gene knockout
Externí odkaz:
https://doaj.org/article/e0e76692aa084cf0b1362aed95cd3b29
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Renal interstitial fibrosis (RIF) is a progressive, irreversible terminal kidney disease with a poor prognosis and high mortality. Angiopoietin-like 4 (ANGPTL4) is known to be associated with fibrosis in various organs, but its im
Externí odkaz:
https://doaj.org/article/eb86df9f10d84aaf87d76242ca06ab22
Autor:
Wentao Hu, Yongming Dai, Fang Liu, Tianshu Yang, Yao Wang, Yiwei Shen, Wenyan Zhou, Dongmei Wu, Leyi Gu, Minfang Zhang, Yan Zhou
Publikováno v:
Insights into Imaging, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Objective To assess renal interstitial fibrosis (IF) using diffusion MRI approaches, and explore whether corticomedullary difference (CMD) of diffusion parameters, combination among MRI parameters, or combination with estimated glomerular fi
Externí odkaz:
https://doaj.org/article/3d0ed9824ab64d22bdd435e8bd8a975a
Autor:
Ping-Kang Chen, Zhong-Yuan Cheng, Ya-Lin Wang, Bao-Jun Xu, Zong-Chao Yu, Zhao-Xia Li, Shang-Ao Gong, Feng-Tao Zhang, Long Qian, Wei Cui, You-Zhen Feng, Xiang-Ran Cai
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background To investigate the feasibility of Diffusion Kurtosis Imaging (DKI) in assessing renal interstitial fibrosis induced by hyperuricemia. Methods A hyperuricemia rat model was established, and the rats were randomly split into the hyp
Externí odkaz:
https://doaj.org/article/bb24a6e315d645fdb4fbb0d22996cbb7
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
The transient receptor potential canonical 6 (TRPC6) channel, a nonselective cation channel that allows the passage of Ca2+, plays an important role in renal diseases. TRPC6 is activated by Ca2+ influx, oxidative stress, and mechanical stress. Studie
Externí odkaz:
https://doaj.org/article/c7b16616dfcf4d9baa62ff649b3be993
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesThis study was conducted to examine the potential health benefits of thonningianin A (TA) on renal injury and interstitial fibrosis in diabetic nephropathy (DN) mice.MethodsIn this study, a DN mice model was established using male C57BL/6 m
Externí odkaz:
https://doaj.org/article/b8d2132510b84848b494002b10ac9823
Autor:
Xianghe Chen, Xinyu Zeng, Xiao Qiu, Chi Liu, Pengcheng Lu, Ziming Shen, Xiangxiang Zhou, Kang Yang
Publikováno v:
Endocrine Connections, Vol 13, Iss 3, Pp 1-11 (2024)
Background: Renal interstitial fibrosis is the pathophysiological basis of type 2 diabetes mellitus (T2DM). Exercise appears to improve kidney interstitial fibrosis in T2DM, in which silent information regulator factor 2-related enzyme 1 (Sirt1) is a
Externí odkaz:
https://doaj.org/article/844331f56ff14024ac3013bb7a716fa0
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-11 (2024)
Abstract All chronic renal disorders eventually lead to renal interstitial fibrosis (RIF). Chronic inflammation and pro-fibrotic substances are familiar companions of the fibrotic process. The Sulforaphane (Sul) molecule is particularly useful in pro
Externí odkaz:
https://doaj.org/article/e882132264d04d35a4e5b6aee4c63a08
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28954- (2024)
Evidence indicates that Baicalein can ameliorate renal interstitial fibrosis by inducing myofibroblast apoptosis and inhibit the RLS3-induced ferroptosis in melanocytes. However, the relationship between renal interstitial fibrosis and anti-ferroptos
Externí odkaz:
https://doaj.org/article/3dba791098864bde9d8cfa5f0d9128d3