Zobrazeno 1 - 10
of 1 462
pro vyhledávání: '"renal cell carcinoma (rcc)"'
Autor:
Zhouhang Zheng, Tianci Yang, Yixuan Li, Pei Qu, Zhiang Shao, Yuan Wang, Wei Chang, Shahzad Muhammad Umar, Jufang Wang, Nan Ding, Wei Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Renal cell carcinoma (RCC) is considered radio- and chemo-resistant. Immune checkpoint inhibitors (ICIs) have demonstrated significant clinical efficacy in advanced RCC. However, the overall response rate of RCC to monotherapy remains limited. Given
Externí odkaz:
https://doaj.org/article/e7ce02beef8843f4a43f9684340271d5
Autor:
Yufei Wang, Eloah Rabello Suarez, Gabriella Kastrunes, Najla Santos Pacheco de Campos, Rabia Abbas, Renata Schmieder Pivetta, Nithyassree Murugan, Ghanbar Mahmoodi Chalbatani, Vincent D’Andrea, Wayne A. Marasco
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Treatment for renal cell carcinoma (RCC) has improved dramatically over the last decade, shifting from high-dose cytokine therapy in combination with surgical resection of tumors to targeted therapy, immunotherapy, and combination therapies.
Externí odkaz:
https://doaj.org/article/739362afabd24506afe9b7a84c657831
Autor:
Nargiz Majidova, Mustafa Seyyar, Demet Işık Bayraktar, Gülhan Dinç, Elfag İsgandarov, Javid Huseynov, Alper Yaşar, Abdussamet Çelebi, Nadiye Sever, Erkam Kocaaslan, Pınar Erel, Yeşim Ağyol, Ali Kaan Güren, Rukiye Arıkan, Selver Işık, Özlem Ercelep, Güzin Demirağ, Umut Kefeli, Osman Köstek, İbrahim Vedat Bayoğlu, Murat Sarı
Publikováno v:
Biomolecules & Biomedicine (2024)
Many developing countries lack access to recommended first-line treatments for metastatic renal cell carcinoma (mRCC), such as immune checkpoint inhibitors (ICIs) or ICI-tyrosine kinase inhibitor (TKI) combinations. As a result, predictive markers ar
Externí odkaz:
https://doaj.org/article/6efa41f2967843798260bb7a256b080e
Autor:
Lassi Luomala, Kalle Mattila, Paula Vainio, Harry Nisén, Teijo Pellinen, Jouni Lohi, Teemu D. Laajala, Petrus Järvinen, Anna‐Riina Koskenniemi, Panu Jaakkola, Tuomas Mirtti
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Background Hypoxia inducible factors, HIF‐1α and HIF‐2α, and their main regulators, the prolyl hydroxylase domain proteins (PHDs), mediate cellular response to hypoxia and contribute to tumor progression in clear cell renal cell carcin
Externí odkaz:
https://doaj.org/article/c03724c045a9453491bfbda1ba93dc88
Autor:
Mohamed Elsayed Ahmed Abdou Fouda, Mahitab Mohamed Rashad Ghoneim, Magdy Elsayed Mohamed Settein, Mohamed Salah Ibrahim Tantawy, Tarek Abdelmoneim El-Diasty
Publikováno v:
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 54, Iss 1, Pp 1-9 (2023)
Abstract Background Radiofrequency ablation (RFA) has an established role in effective treatment of renal cell carcinomas (RCCs), as most of RCCs are diagnosed incidentally in early stages. Long-term follow-up is however important to consolidate the
Externí odkaz:
https://doaj.org/article/ce2995f48c864429a3cb1ab969916ec8
Autor:
Silviu Constantin Latcu, Razvan Bardan, Alin Adrian Cumpanas, Vlad Barbos, Flavia Baderca, Pusa Nela Gaje, Raluca Amalia Ceausu, Serban Comsa, Cristina-Stefania Dumitru, Raluca Dumache, Talida Georgiana Cut, Voichita Elena Lazureanu, Ligia Petrica
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 6, p 557 (2024)
Renal cell carcinoma (RCC) remains incurable in advanced stages. Biomarkers have proven to be quite useful in cancer therapeutics. Herein, we provide a comparative/integrative statistical analysis of seminal immunohistochemistry (IHC) findings for Wi
Externí odkaz:
https://doaj.org/article/22d094dfe43f43bf9c4aa4507ab7f6f3
Autor:
Ghalib Mobaraki, Shuai Shi, Kim M. Smits, Kim Severens, Kim Lommen, Dorit Rennspiess, Emil Chteinberg, Véronique Winnepenninckx, Iryna Samarska, Faisal Klufah, Axel zur Hausen
Publikováno v:
Cancers, Vol 16, Iss 9, p 1746 (2024)
Previous studies have indicated a potential role of diet in the pathogenesis of renal cell carcinoma (RCC). Recently, circular bovine meat and milk factor (BMMF) DNAs have been identified in peritumoral tissues of human colon and breast cancers. Here
Externí odkaz:
https://doaj.org/article/f0942bd6c45e4b48891f3e2c9a8b2905
Publikováno v:
Advanced Ultrasound in Diagnosis and Therapy, Vol 7, Iss 3, Pp 299-301 (2023)
The gastrointestinal tract, particularly the colon, represents a rare site of metastatic carcinoma. It is difficult to diagnose because of its nonspecific clinical and imaging features. Herein, we reported the case of a 64-year-old Asian male who pre
Externí odkaz:
https://doaj.org/article/6f4ae0d9cf984fc79d7dc838bf1cf3f2
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Objective Systematic evaluation of the effectiveness and safety of laparoscopic radical nephrectomy (LRN) for renal tumor (>7 cm). Methods The databases PubMed, Scopus, SinoMed, ScienceDirect, and Google Scholar were systematically searched
Externí odkaz:
https://doaj.org/article/4367d34a3b0a4b9eb101541903978e2a
Autor:
Xiaonan Wang, Wancui Zhu, Qian Long, Enni Chen, Haohui Sun, Xiaodi Li, Hailin Xu, Weizhao Li, Pei Dong, Liru He, Miao Chen, Wuguo Deng
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Renal cell carcinoma (RCC) is not sensitive to immunotherapy and has poor prognosis. DNA methylation regulates gene expression, and its abnormal changes are related to many human diseases. Recently, DNA methylation has been found
Externí odkaz:
https://doaj.org/article/f9a2103dc49446a497e96375417f6156