Zobrazeno 1 - 10
of 704
pro vyhledávání: '"regulatory pathways"'
Autor:
Asmus Cosmos Skovgaard, Afsaneh Mohammadnejad, Hans Christian Beck, Qihua Tan, Mette Soerensen
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Cardiovascular diseases (CVDs) are major causes of mortality and morbidity worldwide; yet the understanding of their molecular basis is incomplete. Multi-omics studies have significant potential to uncover these mechanisms, but su
Externí odkaz:
https://doaj.org/article/41681d54596c4218b38a874c3f35ba32
Autor:
James Bernstein, Kim Huynh-Ba, Patrick Lynch, Thomas Oliver, Reza Oliyai, Scott W. Roberts, Andrea Schirmer, David Schwinke, Kin Tang, Jessica Ursin
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract The American Association of Pharmaceutical Scientists (AAPS) Chemistry, Manufacturing, and Control (CMC) Community hosted a virtual panel discussion on July 15, 2022, to provide a forum to discuss industry and regulator CMC challenges associ
Externí odkaz:
https://doaj.org/article/9928b46a96fc4ac4a379cb5a91c7fc4c
Autor:
Mariia V. Maksimova, Ghislaine J. M. W. van Thiel, Yke Tromp, Rosan Lechner, Johannes J. M. van Delden, Lourens T. Bloem
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The European Medicines Agency’s conditional marketing authorization (CMA) aims to expedite patient access to medicines for unmet medical needs by shifting a part of the drug development process post-authorization. We highlight ethical issues surrou
Externí odkaz:
https://doaj.org/article/07f3fa560b54482783616b74dd73c243
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Abscisic acid (ABA) and nitric oxide (NO), as unique signaling molecules, are involved in plant growth, developmental processes, and abiotic stresses. However, the interaction between ABA and NO under abiotic stresses has little been worked out at pr
Externí odkaz:
https://doaj.org/article/8d372ebab0d34bfda531eb5d9d33e616
Autor:
Antropova Evgeniya A., Khlebodarova Tamara M., Demenkov Pavel S., Volianskaia Anastasiia R., Venzel Artur S., Ivanisenko Nikita V., Gavrilenko Alexandr D., Ivanisenko Timofey V., Adamovskaya Anna V., Revva Polina M., Kolchanov Nikolay A., Lavrik Inna N., Ivanisenko Vladimir A.
Publikováno v:
Journal of Integrative Bioinformatics, Vol 20, Iss 3, Pp 597-600 (2023)
Hepatocellular carcinoma (HCC) has been associated with hepatitis C viral (HCV) infection as a potential risk factor. Nonetheless, the precise genetic regulatory mechanisms triggered by the virus, leading to virus-induced hepatocarcinogenesis, remain
Externí odkaz:
https://doaj.org/article/7113a3f25d9d439788d411759f2c4c79
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTBeneficial microbial symbionts that are horizontally acquired by their animal hosts undergo a lifestyle transition from free-living in the environment to associating with host tissues. In the model symbiosis between the Hawaiian bobtail squid
Externí odkaz:
https://doaj.org/article/f57eef619d92473b86b3699d478327f8
Autor:
Thomas P. Chacko, J. Tory Toole, Matthew C. Morris, Jeffrey Page, Robert D. Forsten, John P. Barrett, Matthew J. Reinhard, Ryan C. Brewster, Michelle E. Costanzo, Gordon Broderick
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionIn 2016 diplomatic personnel serving in Havana, Cuba, began reporting audible sensory phenomena paired with onset of complex and persistent neurological symptoms consistent with brain injury. The etiology of these Anomalous Health Inciden
Externí odkaz:
https://doaj.org/article/2fc1da81a36f4437a6624aaecfecb611
Autor:
Vamsidhar Reddy Netla, Harshraj Shinde, Gulshan Kumar, Ambika Dudhate, Jong Chan Hong, Ulhas Sopanrao Kadam
Publikováno v:
Current Plant Biology, Vol 35, Iss , Pp 100289- (2023)
The development of sequencing methods has resulted in the investigation of many unexplored research areas. Among the different sequencing methods, single-cell transcriptomics is versatile and has completely changed the researchers' perception of biol
Externí odkaz:
https://doaj.org/article/e51d3e9923ff4642836d49a56a0ac284
Publikováno v:
Brain Circulation, Vol 9, Iss 4, Pp 228-239 (2023)
BACKGROUND: Ischemic stroke (IS) is a life-threatening condition with limited treatment options; thus, finding the potential key genes for novel therapeutic targets is urgently needed. This study aimed to explore novel candidate genes and pathways of
Externí odkaz:
https://doaj.org/article/87cc690dabd64a5e9363fd61b2f0edd3
Autor:
E. A. Antropova, T. M. Khlebodarova, P. S. Demenkov, A. S. Venzel, N. V. Ivanisenko, A. D. Gavrilenko, T. V. Ivanisenko, A. V. Adamovskaya, P. M. Revva, I. N. Lavrik, V. A. Ivanisenko
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 8, Pp 733-742 (2023)
Hepatitis C virus (HCV) is a risk factor that leads to hepatocellular carcinoma (HCC) development. Epigenetic changes are known to play an important role in the molecular genetic mechanisms of virus-induced oncogenesis. Aber rant DNA methylation is a
Externí odkaz:
https://doaj.org/article/a780a4a984f145ff90b545ffa343b136