Zobrazeno 1 - 10
of 28
pro vyhledávání: '"regulatory metabolism"'
Autor:
Fatemeh Lavajoo Bolgouri, Bahram Falahatkar, Miquel Perelló-Amorós, Fatemeh Moshayedi, Iraj Efatpanah, Joaquim Gutiérrez
Publikováno v:
Animals, Vol 14, Iss 21, p 3089 (2024)
The pikeperch (Sander lucioperca) is an economically important freshwater fish and a valuable food with high market acceptance. It is undergoing important changes in growth and regulatory metabolism during the ontogeny. Hence, the current study aims
Externí odkaz:
https://doaj.org/article/b586ebbe7d3e4887a32df7b49bf24b75
Akademický článek
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Akademický článek
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Autor:
de Kivit, Sander, Mensink, Mark, Hoekstra, Anna T, Berlin, Ilana, Derks, Rico J E, Both, Demi, Aslam, Muhammad A, Amsen, Derk, Berkers, Celia R, Borst, Jannie, Sub Immunopharmacology, Sub Biomol.Mass Spectrometry & Proteom., Veterinaire biochemie, dB&C FR-RMSC RMSC, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Metabolism, 2(10), 1046. Springer Berlin
Nature Metabolism, 2(10), 1046-1061. Springer Berlin
Nature Metabolism, 2(10), 1046-1061. NATURE RESEARCH
NATURE METABOLISM
Nature Metabolism, 2(10), 1046-1061. Springer Berlin
Nature Metabolism, 2(10), 1046-1061. NATURE RESEARCH
NATURE METABOLISM
Following activation, conventional T (T-conv) cells undergo an mTOR-driven glycolytic switch. Regulatory T (T-reg) cells reportedly repress the mTOR pathway and avoid glycolysis. However, here we demonstrate that human thymus-derived T-reg (tT(reg))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1f1f70f911a89ed95b9d7897d7a565
https://dspace.library.uu.nl/handle/1874/418729
https://dspace.library.uu.nl/handle/1874/418729
Autor:
Pedro Romero, Marion Bossennec, Isabelle Durand, Bertrand Dubois, Christelle Machon, David Bauché, Julien Faget, Nicolas Gourdin, Christophe Caux, Jérôme Guitton, Julien C. Marie, Camilla Jandus, Nicolas Chopin, Olivier Tredan, Christine Ménétrier-Caux, Céline Rodriguez, Selena Vigano
Publikováno v:
Cancer Research, Vol. 78, No 13 (2018) pp. 3604-3618
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Cancer research, vol. 78, no. 13, pp. 3604-3618
Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Cancer research, vol. 78, no. 13, pp. 3604-3618
Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
The production of CD73-derived adenosine (Ado) by Tregs has been proposed as a resistance mechanism to anti-PD-1 therapy in murine tumor models. We reported that human Tregs express the ectonucleotidase CD39, which generates AMP from ATP, but do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8375fbfa2c51d166ee5ae1ba8adac560
https://doi.org/10.1158/0008-5472.can-17-2405
https://doi.org/10.1158/0008-5472.can-17-2405
Autor:
Haiping Wang, Taha Merghoub, Sarah-Maria Fendt, Camilla Jandus, Ping-Chih Ho, Xin Xie, Fabien Franco, Juan Fernández-García, Etienne Meylan, Ira Goldberg, Chin Hsien Tsai, Yao Chen Tsui, Isabell Schulze, Roy L. Silverstein, Roberta Zappasodi, Jedd D. Wolchok, Marcel P. Trefny, Alfred Zippelius, Florence Picard, Syed Raza Mohmood
Publikováno v:
Nature immunology, vol. 21, no. 3, pp. 298-308
Nature Immunology, Vol. 21, No 3 (2020) pp. 298-308
Nature Immunology
Nature Immunology, Vol. 21, No 3 (2020) pp. 298-308
Nature Immunology
Depleting regulatory T cells (T-reg cells) to counteract immunosuppressive features of the tumor microenvironment (TME) is an attractive strategy for cancer treatment; however, autoimmunity due to systemic impairment of their suppressive function lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0890f7d204d5ad48cba3ed61051edb49
https://pubmed.ncbi.nlm.nih.gov/32066948
https://pubmed.ncbi.nlm.nih.gov/32066948
Autor:
Katharina Littringer, Van Du T. Tran, Nicole Joller, Dominique Sanglard, Florian R. Kirchner, Simon Altmeier, Salomé LeibundGut-Landmann, Franziska Schönherr, Marco Pagni, Christina Lemberg
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in immunology, vol. 10, pp. 330
Frontiers in Immunology, Vol 10 (2019)
Frontiers in immunology, vol. 10, pp. 330
Controlled immune activation in response to commensal microbes is critical for the maintenance of stable colonization and prevention of microbial overgrowth on epithelial surfaces. Our understanding of the host mechanisms that regulate bacterial comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f8ff6cce12386bdf7325466ee3c2e9
https://www.zora.uzh.ch/id/eprint/169536/
https://www.zora.uzh.ch/id/eprint/169536/
Autor:
Marta Mastrogiovanni, Paola Grazioli, Antonio Francesco Campese, Loretta Tuosto, Balbino Alarcón, Silvana Caristi, Cédric Favre, Nicla Porciello, Francesca Spadaro, Jacques A. Nunès, Isabella Screpanti, Martina Kunkl, Michela Muscolini, Aldo Borroto
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
CD28 superagonistic antibodies (CD28SAb) can preferentially activate and expand immunosuppressive regulatory T cells (Treg) in mice. However, pre-clinical trials assessing CD28SAbs for the therapy of autoimmune diseases reveal severe systemic inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29edf0332e8787c555c9b6ff4b29196e
https://hal.archives-ouvertes.fr/hal-01772994
https://hal.archives-ouvertes.fr/hal-01772994
Autor:
Sébastien Fleury, Severine Navarro, Nicolas Glaichenhaus, A Kanda, David Dombrowicz, Anne Lazzari, Valérie Julia
Publikováno v:
Mucosal Immunology
Mucosal Immunology, Nature Pub. Group, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
Mucosal Immunology, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
Mucosal Immunology, Nature Pub. Group, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
Mucosal Immunology, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
International audience; Allergic asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness (AHR), lung infiltration of Th2 cells, and high levels of IgE. To date, allergen-specific immunotherapy (SIT) is the only treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d213c53e8f68090bfc11e41706a54b
https://doi.org/10.1038/mi.2014.115
https://doi.org/10.1038/mi.2014.115
Autor:
Wim Janssens, Luc VanderElst, Thierry VandenDriessche, Vincent Carlier, Marinee Chuah, Marc Jacquemin, Jeroen Vanoirbeek, Roxana Roohi Ahangarani, Birgit Weynand, Jean-Marie Saint-Remy
Publikováno v:
The Journal of Immunology. 183:8232-8243
Regulatory T cells (Tregs) hold much promise for the therapy of allergy and autoimmunity, but their use is hampered by lack of Ag specificity (natural Tregs) and difficulty to expand in vitro or in vivo (adaptive Tregs). We designed a method for in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772ae0e219f6c6858dd4c2d9a9a0dc97
https://doi.org/10.4049/jimmunol.0901777
https://doi.org/10.4049/jimmunol.0901777