Zobrazeno 1 - 10
of 113
pro vyhledávání: '"regulatory B cells (Bregs)"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Radiation-induced lung injury is a common complication associated with radiotherapy. It is characterized by early-stage radiation pneumonia and subsequent radiation pulmonary fibrosis. However, there is currently a lack of effective therapeutic strat
Externí odkaz:
https://doaj.org/article/c4d375a6a61b414081055191a4d3d75d
Autor:
Gillian Dao Nyesiga, Lieneke Pool, Pavlos C. Englezou, Terese Hylander, Lars Ohlsson, Daniel Appelgren, Anette Sundstedt, Kristina Tillerkvist, Hanne R. Romedahl, Maria Wigren
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cells (DCs) are mediators between innate and adaptive immunity and vital in initiating and modulating antigen-specific immune responses. The most important site for induction of tolerance is the gut mucosa, where TGF-β, retinoic acid, and
Externí odkaz:
https://doaj.org/article/f2c2984fc5da4eb8b7fc390b4c372a1e
Autor:
Roxana Zogorean, Stefan Wirtz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract, defined by a clinical relapse-remitting course. Affecting people worldwide, the origin of IBD is still undefined, arising as a consequence of the intera
Externí odkaz:
https://doaj.org/article/57805a2c8e8a45e2b63ca9fad1bb7fb8
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Considerable experimental and clinical evidences have proved that human umbilical cord mesenchymal stem cells (UC-MSCs) transplantation was powerful in systemic lupus erythematosus (SLE) treatment. MSCs could upregulate regulatory
Externí odkaz:
https://doaj.org/article/67fe68ef81f74c1d8fc8865cc667b4d9
Autor:
Diaoyi Tan, Wei Yin, Fei Guan, Wanjiang Zeng, Pamela Lee, Fabio Candotti, Louisa K James, Niels Olsen Saraiva Camara, S.M. Mansour Haeryfar, Yan Chen, Kamel Benlagha, Lewis Zhichang Shi, Jiahui Lei, Quan Gong, Zheng Liu, Chaohong Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
B cells are the core components of humoral immunity. A mature B cell can serve in multiple capacities, including antibody production, antigen presentation, and regulatory functions. Forkhead box P3 (FoxP3)-expressing regulatory T cells (Tregs) are ke
Externí odkaz:
https://doaj.org/article/caf5913442b44c6e8bfedb051d28009b
Autor:
Wei Lee, Li‐Tzu Wang, Men‐Luh Yen, Pei‐Ju Hsu, Yu‐Wei Lee, Ko‐Jiunn Liu, Kuo‐I Lin, Yu‐Wen Su, Huey‐Kang Sytwu, B. Linju Yen
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 711-724 (2021)
Abstract Multipotent human mesenchymal stromal cells (MSCs) from multiple organs including the bone marrow (BM) and placenta harbor clinically relevant immunomodulation best demonstrated toward T lymphocytes. Surprisingly, there is limited knowledge
Externí odkaz:
https://doaj.org/article/5d3d40e88601401c8c871b550f8fe7e3
Publikováno v:
Liver Research, Vol 5, Iss 1, Pp 11-15 (2021)
Chronic hepatitis B (CHB) remains a global health problem. The persistence of hepatitis B surface antigen (HBsAg) in the blood for longer than 6 months after the initial infection is a sign of CHB. The therapeutic goal for the functional cure of CHB
Externí odkaz:
https://doaj.org/article/8a804814383a459ba8dcb270a1219e60
Autor:
Tetsuya Honda, Yuki Honda Keith
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Skin is a frontline organ that is continuously exposed to external stimuli, including pathogens. Various immune cells reside in the skin under physiological conditions and protect the body from the entry of pathogens/antigens by interacting with each
Externí odkaz:
https://doaj.org/article/e199ecc8ed5445a9801c6a89df25f14e
Autor:
Mitra Abbasifard, Zahra Kamiab, Mohammad Hasani, Amir Rahnama, Pooya Saeed-Askari, Hossein Khorramdelazad
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background The immunosuppressive effects of regulatory B-cells (Bregs) and their immunosuppressive cytokines on immune responses in autoimmune disorders, mainly systemic lupus erythematosus (SLE), have been recently established. Therefore, t
Externí odkaz:
https://doaj.org/article/904a9be09daa456daa77b471f5a5f451
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interleukin (IL)-35-secreting B (IL-35+B) cells are critical regulators in autoimmune and infectious diseases and exert suppressive functions in parallel with IL-10-producing B (B10) cells. However, the role of IL-35+B cells in persistent hepatitis B
Externí odkaz:
https://doaj.org/article/f611c4aa7dd84bafbd13761554f0666f