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Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

Autor: Carlos A. Aguilar-Salinas, Sandhya Rajkumar, María Teresa Tusié-Luna, Linda Liliana Muñoz-Hernandez, Amogha Koka, Zong Miao, David Z. Pan, Karen L. Mohlke, Kirsi H. Pietiläinen, Nicholas Mancuso, Marcus Alvarez, Arthur Ko, Jussi Pihlajamäki, Kristina M. Garske, Dorota Kaminska, Päivi Pajukanta, Miguel Herrera-Hernandez, Janet S. Sinsheimer, Markku Laakso, Caroline Comenho, Seung Hyuk T. Lee

Publikováno v: Genome medicine, vol 13, iss 1
Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)
Genome Medicine

Background Obesity predisposes individuals to multiple cardiometabolic disorders, including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat from lean mass, the metabolically detrimental abdominal obesity has been est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0622c91bcfbc8ae2f33ba68652c45ee7
https://escholarship.org/uc/item/5482z1w8

Nuclear Receptors for Thyroid Hormone: Evidence for Nonrandom Distribution within Chromatin

Autor: Charles, M. Arthur, Ryffel, Gerhart U., Obinata, Masuo, McCarthy, Brian J., Baxter, John D.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1975 May 01. 72(5), 1787-1791.

Externí odkaz: https://www.jstor.org/stable/64584

Deregulated Expression of the Imprinted DLK1-DIO3 Region in Glioblastoma Stem-like Cells: Tumor Suppressor Role of lncRNA MEG3

Autor: Alessandro Giuliani, Valentina Lulli, Maurizio Genuardi, Maurizio Martini, Giorgio Giurato, Roberto Pallini, Quintino Giorgio D'Alessandris, Giuseppe Marangi, Ramona Ilari, Stefano Giannetti, Alessandra Boe, Agnese Novelli, Lucia Ricci-Vitiani, Giorgia Castellani, Michele Signore, Giovanna Marziali, Mauro Biffoni, Mariachiara Buccarelli, Serena Spartano

Publikováno v: Neuro-Oncology

Background Glioblastoma (GBM) stemlike cells (GSCs) are thought to be responsible for the maintenance and aggressiveness of GBM, the most common primary brain tumor in adults. This study aims at elucidating the involvement of deregulations within the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ecadf2a142acd658c4cb0e8248c548
http://hdl.handle.net/11386/4748419

MiR-144: A New Possible Therapeutic Target and Diagnostic/Prognostic Tool in Cancers

Autor: Nicola Silvestris, Amir Baghbanzadeh, Behzad Mansoori, Oronzo Brunetti, Parviz Vahedi, Afshin Derakhshani, Meysam Rahmati, Omid Kooshkaki, Behzad Baradaran, Zohre Rezaei

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 2578, p 2578 (2020)
International Journal of Molecular Sciences
Kooshkaki, O, Rezaei, Z, Rahmati, M, Vahedi, P, Derakhshani, A, Brunetti, O, Baghbanzadeh, A, Mansoori, B, Silvestris, N & Baradaran, B 2020, ' MiR-144 : A New Possible Therapeutic Target and Diagnostic/Prognostic Tool in Cancers ', International Journal of Molecular Sciences, vol. 21, no. 7, 2578 . https://doi.org/10.3390/ijms21072578

MicroRNAs (miRNAs) are small and non-coding RNAs that display aberrant expression in the tissue and plasma of cancer patients when tested in comparison to healthy individuals. In past decades, research data proposed that miRNAs could be diagnostic an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4334d1f3a9cf7953f51c2bc8e1eaf6fa
https://doi.org/10.3390/ijms21072578