Výsledky vyhledávání - "regulated exocytosis"

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Imaging the rapid yet transient accumulation of regulatory lipids, lipid kinases, and protein kinases during membrane fusion, at sites of exocytosis of MMP-9 in MCF-7 cells

Autor: Dominique C. Stephens, Tyrel W. Powell, Justin W. Taraska, Dinari A. Harris

Publikováno v: Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-19 (2020)

Abstract Background The regulation of exocytosis is physiologically vital in cells and requires a variety of distinct proteins and lipids that facilitate efficient, fast, and timely release of secretory vesicle cargo. Growing evidence suggests that r

Externí odkaz: https://doaj.org/article/be62ceafd469494abbaf7651cfbf9c94

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Akademický článek

Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha

Autor: Marek Kučka, Arturo E. Gonzalez-Iglesias, Melanija Tomić, Rafael M. Prévide, Kosara Smiljanic, Srdjan J. Sokanovic, Patrick A. Fletcher, Arthur Sherman, Tamas Balla, Stanko S. Stojilkovic

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

The role of calcium, but not of other intracellular signaling molecules, in the release of pituitary hormones by exocytosis is well established. Here, we analyzed the contribution of phosphatidylinositol kinases (PIKs) to calcium-driven prolactin (PR

Externí odkaz: https://doaj.org/article/f783d8878b0d4c43b10b8a9486cd2f86

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Akademický článek

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis

Autor: Bello, Oscar D., Jouannot, Ouardane, Chaudhuri, Arunima, Stroeva, Ekaterina, Coleman, Jeff, Volynski, Kirill E., Rothman, James E., Krishnakumar, Shyam S.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 Aug 01. 115(32), E7624-E7631.

Externí odkaz: https://www.jstor.org/stable/26530112

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Akademický článek

A multimodal electrochemical approach to measure the effect of zinc on vesicular content and exocytosis in a single cell model of ischemia

Autor: Ying Wang, Chaoyi Gu, Andrew G. Ewing

Publikováno v: QRB Discovery, Vol 2 (2021)

Zinc ion is essential for normal brain function that modulates synaptic activity and neuronal plasticity and it is associated with memory formation. Zinc is considered to be a contributing factor to the pathogenesis of ischemia, but the association b

Externí odkaz: https://doaj.org/article/caea059ddca94c5db8d8fbec679e1321

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Mistargeting of secretory cargo in retromer-deficient cells

Autor: Sarah D. Neuman, Erica L. Terry, Jane E. Selegue, Amy T. Cavanagh, Arash Bashirullah

Publikováno v: Disease Models & Mechanisms, Vol 14, Iss 1 (2021)

Intracellular trafficking is a basic and essential cellular function required for delivery of proteins to the appropriate subcellular destination; this process is especially demanding in professional secretory cells, which synthesize and secrete mass

Externí odkaz: https://doaj.org/article/a8798606cbab4b25993df6b17fd9c54c

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