Zobrazeno 1 - 10
of 274
pro vyhledávání: '"reduced nicotinamide adenine dinucleotide phosphate"'
Akademický článek
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Autor:
Getachew Debas Belew, Joao Silva, Joao Rito, Ludgero Tavares, Ivan Viegas, Jose Teixeira, Paulo J. Oliveira, Maria Paula Macedo, John G. Jones
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2050-2056 (2019)
Deuterated water (2H2O) is widely used for measuring de novo lipogenesis (DNL). 2H is incorporated into fatty acids via exchange between body water and the hydrogens of acetyl-CoA, malonyl-CoA, and NADPH. Previous studies concluded that these exchang
Externí odkaz:
https://doaj.org/article/a1eb5a82beb84feab5840a64f5899ac2
Autor:
Ahmed S. Ibrahim, Sally Elshafey, Hassan Sellak, Khaled A. Hussein, Mohamed El-Sherbiny, Mohammed Abdelsaid, Nasser Rizk, Selina Beasley, Amany M. Tawfik, Sylvia B. Smith, Mohamed Al-Shabrawey
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 3, Pp 599-611 (2015)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived metabolites, in this proces
Externí odkaz:
https://doaj.org/article/a9eac5bb558f49d4ab2ac1cd032e6672
Autor:
Kenneth K.W. To, Jiang Ma, Stella Chai, Chunyuan Zhang, Chun Yin, Sheng Yao, Xu Wu, Thomas Efferth, Yang Ye, Onat Kadioglu, Ge Lin
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)
Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10ca45cdbb87dcf2ef29e5865d5f864
https://doi.org/10.1016/j.apsb.2020.12.021
https://doi.org/10.1016/j.apsb.2020.12.021
Publikováno v:
Journal of Medicine and Life
Nowadays, chronic alcoholism and its health implications represent a global concern. Over three million deaths are linked to chronic alcohol intake every year. This article aims to spread awareness about the negative impact ethanol can have on almost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0628a91d0b63c00b579082571aeb3494
http://europepmc.org/articles/PMC8742892
http://europepmc.org/articles/PMC8742892
Publikováno v:
Molecular medicine reports. 26(6)
Calcium (Ca2+) signaling is the first messenger signal exhibited by osteocytes. The present study aimed to better understand the link between Ca2+ concentration, and the levels of bone mineralization regulator proteins [phosphate-regulating neutral e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959c3d17e448b5969b79b1ea4d73de0b
https://pubmed.ncbi.nlm.nih.gov/36281920
https://pubmed.ncbi.nlm.nih.gov/36281920
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Guoan Zhao, Xuehui Wang, Libo Wang, Chaoyuan Zhou, Ajay M. Shah, Min Zhang, Yuan Ding, Yating Pan, Huibing Liu
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 35-49 (2020)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • The reactive oxygen species–generating enzyme Nox2 is up-regulated in the leaflets of both rabbit and human with CAVD. • Nox2 is markedly induced in cultured porcine AVICs after osteogenic stimulation. Knockdow
Highlights • The reactive oxygen species–generating enzyme Nox2 is up-regulated in the leaflets of both rabbit and human with CAVD. • Nox2 is markedly induced in cultured porcine AVICs after osteogenic stimulation. Knockdow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4dcdfdf0194280e47c67ff6d7154c1
https://doi.org/10.1016/j.jacbts.2019.10.004
https://doi.org/10.1016/j.jacbts.2019.10.004
Autor:
Massimiliano Cuccioloni, Matteo Mozzicafreddo, Michele Spina, Chi Nhan Tran, Maurizio Falconi, Anna Maria Eleuteri, Mauro Angeletti
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 5, Pp 897-907 (2011)
Hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) is the rate-controlling enzyme of cholesterol synthesis, and owing to its biological and pharmacological relevance, researchers have investigated several compounds capable of modulating its activity with
Externí odkaz:
https://doaj.org/article/98e96ece80f445579d66554389b8c8d9