Zobrazeno 1 - 10
of 89
pro vyhledávání: '"rectal drug delivery"'
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100176- (2023)
Infliximab is a monoclonal antibody that plays an important role in the management and treatment of chronic inflammatory bowel diseases (IBD). Due to its macromolecular structure, its delivery through the oral route is challenging, limiting its admin
Externí odkaz:
https://doaj.org/article/e7988ed516c34418807a1e88994d79de
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1865 (2023)
Rectal drug administration could offer advantages in the delivery of medicines for children by avoiding swallowability issues, improving stability and enabling administration by caregivers. This study aimed to evaluate the rectal bioavailability of h
Externí odkaz:
https://doaj.org/article/0918d4d47caf454980885a3a946bc52e
Autor:
Ritu Rathi, Sanshita, Alpesh Kumar, Vivekanand Vishvakarma, Kampanart Huanbutta, Inderbir Singh, Tanikan Sangnim
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2210 (2022)
The rectal route is an effective route for the local and systemic delivery of active pharmaceutical ingredients. The environment of the rectum is relatively constant with low enzymatic activity and is favorable for drugs having poor oral absorption,
Externí odkaz:
https://doaj.org/article/43068220ee9b445586f9ab6fc5ed89db
Akademický článek
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Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1865
Rectal drug administration could offer advantages in the delivery of medicines for children by avoiding swallowability issues, improving stability and enabling administration by caregivers. This study aimed to evaluate the rectal bioavailability of h
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5500 (2021)
Rectal drug delivery is an effective alternative to oral and parenteral treatments. This route allows for both local and systemic drug therapy. Traditional rectal dosage formulations have historically been used for localised treatments, including lax
Externí odkaz:
https://doaj.org/article/00a70a827df1420c9e7d4e21b7b0a5ab
Autor:
Mario Jug, Anita Hafner, Jasmina Lovrić, Maja Lusina Kregar, Ivan Pepić, Željka Vanić, Biserka Cetina-Čižmek, Jelena Filipović-Grčić
Publikováno v:
ADMET and DMPK, Vol 5, Iss 3, Pp 173-182 (2017)
In vitro dissolution/release tests are an indispensable tool in the drug product development, its quality control and the regulatory approval process. Mucosal drug delivery systems are designed to provide both local and systemic drug action following
Externí odkaz:
https://doaj.org/article/c99e6ed6ea464c3598babb1a1ae55e0a
Autor:
Iria Seoane-Viaño, Noemí Gómez-Lado, Héctor Lázare-Iglesias, Xurxo García-Otero, José Ramón Antúnez-López, Álvaro Ruibal, Juan Jesús Varela-Correa, Pablo Aguiar, Abdul W. Basit, Francisco J. Otero-Espinar, Miguel González-Barcia, Alvaro Goyanes, Asteria Luzardo-Álvarez, Anxo Fernández-Ferreiro
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 563 (2020)
The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel disease. Blends of Gelucire
Externí odkaz:
https://doaj.org/article/c822ff86ea464786b418913444786d10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
M. Melissa Peet, Vivek Agrahari, Sharon M. Anderson, Homaira Hanif, Onkar N. Singh, Andrea R. Thurman, Gustavo F. Doncel, Meredith R. Clark
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 374 (2019)
The development of topical inserts for the prevention of sexually transmitted infections (STIs), particularly human immunodeficiency virus (HIV), represents a promising alternative to oral and parenteral pre-exposure prophylaxis (PrEP) dosage forms.
Externí odkaz:
https://doaj.org/article/66febb17828a4117a135be7ce3c80bba