Zobrazeno 1 - 10
of 491
pro vyhledávání: '"recombinant BCG"'
Autor:
Danang Fang, Ruihuan Wang, Xueting Fan, Machao Li, Chenyu Qian, Bin Cao, Jinjie Yu, Haican Liu, Yongliang Lou, Kanglin Wan
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTTuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) persistently kills nearly 1.5 million lives per year in the world, whereas the only licensed TB vaccine BCG exhibits unsatisfactory efficacy in adults. Taking BCG as a vehicle to ex
Externí odkaz:
https://doaj.org/article/4ee9fc4a68624941b96eca549443a7e9
Autor:
Moagi Tube Shaku, Peter K Um, Karl L Ocius, Alexis J Apostolos, Marcos M Pires, William R Bishai, Bavesh D Kana
Publikováno v:
eLife, Vol 13 (2024)
Mechanisms by which Mycobacterium tuberculosis (Mtb) evades pathogen recognition receptor activation during infection may offer insights for the development of improved tuberculosis (TB) vaccines. Whilst Mtb elicits NOD-2 activation through host reco
Externí odkaz:
https://doaj.org/article/2ec1c0baa609422f812164c530156245
Autor:
Monalisa Martins Trentini, Dunia Rodriguez, Alex Issamu Kanno, Cibelly Goulart, Michelle Darrieux, Luciana Cezar de Cerqueira Leite
Publikováno v:
Vaccines, Vol 12, Iss 2, p 122 (2024)
Pneumococcal diseases are an important public health problem, with high mortality rates in young children. Although conjugated pneumococcal vaccines offer high protection against invasive pneumococcal diseases, this is restricted to vaccine serotypes
Externí odkaz:
https://doaj.org/article/6e676a49476449608786d271faf919d6
Autor:
Lázaro Moreira Marques-Neto, Monalisa Martins Trentini, Alex Issamu Kanno, Dunia Rodriguez, Luciana Cezar de Cerqueira Leite
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Vaccine-induced protection against Mycobacterium tuberculosis (Mtb) is usually ascribed to the induction of Th1, Th17, and CD8+ T cells. However, protective immune responses should also involve other immune cell subsets, such as memory T cells. We ha
Externí odkaz:
https://doaj.org/article/a8a9c37b4b9548f6844c3914330da558
Autor:
Ruihuan Wang, Xueting Fan, Da Xu, Machao Li, Xiuqin Zhao, Bin Cao, Chengyu Qian, Jinjie Yu, Dan’ang Fang, Yujie Gu, Kanglin Wan, Haican Liu
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1738 (2023)
Bacillus Calmette–Guérin (BCG) is the only widely used prophylactic tuberculosis (TB) vaccine that can prevent severe TB in infants. However, it provides poor protection in adults, and therefore, there is ongoing research into new TB vaccines and
Externí odkaz:
https://doaj.org/article/18a3bd6a2f8a45dabf3b58c5c4725d92
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bacillus Calmette-Guerin (BCG) has been used as a vaccine against tuberculosis since 1921 and remains the only currently approved vaccine for this infection. The recent discovery that BCG protects against initial infection, and not just against progr
Externí odkaz:
https://doaj.org/article/c547c42d72854c42a6de49cfe1782ea5
Autor:
Monalisa Martins Trentini, Alex Issamu Kanno, Dunia Rodriguez, Lazaro Moreira Marques-Neto, Silas Fernandes Eto, Ana Marisa Chudzinki-Tavassi, Luciana Cezar de Cerqueira Leite
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) is one of the deadliest infectious diseases around the world. Prevention is based on the prophylactic use of BCG vaccine, effective in infants but as protection wanes with time, adults are less protected. Additionally, chemotherapy
Externí odkaz:
https://doaj.org/article/773bbf48f4ca4016bd1f8efd6dccce1d
Akademický článek
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