Elevated origin recognition complex subunit 6 expression promotes non-small cell lung cancer cell growth.

Autor: Sang YH; Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Soochow University, Suzhou, China., Luo CY; Department of Pathology, Affiliated Hospital of Youjiang Medical University for Nationalities and Key Laboratory of Molecular Pathology in Tumors of Guangxi Higher Education Institutions, Baise, China., Huang BT; Department of Thoracic Surgery, Binzhou Medical University Hospital, Binzhou, China., Wu S; Respiratory Intensive Care Unit, Affiliated Hospital of YouJiang Medical University for Nationalities, Baise, China., Shu J; Department of Thoracic and Cardiovascular Surgery, Taicang Affiliated Hospital of Soochow University The First People's Hospital of Taicang, Taicang, China. yuren123456789@163.com., Lan CG; Department of Pathology, Affiliated Hospital of Youjiang Medical University for Nationalities and Key Laboratory of Molecular Pathology in Tumors of Guangxi Higher Education Institutions, Baise, China. lchy2005@163.com., Zhang F; Department of Thoracic and Cardiovascular Surgery, The Second Affiliated Hospital of Nantong University, The First People's Hospital of Nantong, Nantong, China. zhangfq822@163.com.

Publikováno v: Cell death & disease [Cell Death Dis] 2024 Sep 30; Vol. 15 (9), pp. 700. Date of Electronic Publication: 2024 Sep 30.

Origin recognition complex subunit 6 (ORC6) is a key mediator of LPS-induced NFκB activation and the pro-inflammatory response.

Autor: Xie Z; Emergency Department, Minhang Hospital, Fudan University, Shanghai, China., Lu H; Emergency Department, Minhang Hospital, Fudan University, Shanghai, China., Zheng J; Emergency Department, Minhang Hospital, Fudan University, Shanghai, China., Song J; Emergency Department, Minhang Hospital, Fudan University, Shanghai, China. song_jianfeng@fudan.edu.cn., Sun K; Emergency Department, Minhang Hospital, Fudan University, Shanghai, China. sunkeyu@fudan.edu.cn.

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Aug 14; Vol. 22 (1), pp. 399. Date of Electronic Publication: 2024 Aug 14.

Ordered and disordered regions of the Origin Recognition Complex direct differential in vivo binding at distinct motif sequences.

Autor: Chappleboim M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Naveh-Tassa S; Department of Chemical and structural Biology, Weizmann Institute of Science, Rehovot, Israel., Carmi M; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel., Levy Y; Department of Chemical and structural Biology, Weizmann Institute of Science, Rehovot, Israel., Barkai N; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Jun 10; Vol. 52 (10), pp. 5720-5731.

scRNA-seq reveals that origin recognition complex subunit 6 regulates mouse spermatogonial cell proliferation and apoptosis via activation of Wnt/β-catenin signaling.

Autor: Liu SW; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Luo JQ; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Zhao LY; Department of Urology, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai 519000, China., Ou NJ; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Chao-Yang; Department of Urology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China., Zhang YX; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Bai HW; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Sun HF; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Zhang JX; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Yao CC; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Li P; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Tian RH; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Li Z; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China., Zhu ZJ; Department of Andrology, Center for Men's Health, Urologic Medical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.; Shanghai Key Lab of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China.

Publikováno v: Asian journal of andrology [Asian J Androl] 2024 Jan 01; Vol. 26 (1), pp. 46-56. Date of Electronic Publication: 2023 Sep 05.

Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression.

Autor: Zhu J; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Chen Q; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Zeng L; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Gao H; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Wu T; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., He Y; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Xu J; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Pang J; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Peng J; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Deng Y; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Han Y; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China., Yi W; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, Hunan, China.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Oct 12; Vol. 14, pp. 1236806. Date of Electronic Publication: 2023 Oct 12 (Print Publication: 2023).