Zobrazeno 1 - 10
of 5 525
pro vyhledávání: '"rat plasma"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Background Amivantamab is a monoclonal bispecific anti-EGFR-MET antibody used to treat non-small cell lung cancer. There were no published methods using a liquid chromatographic—tandem mass spectrometric approach to develop and validate a
Externí odkaz:
https://doaj.org/article/c7ae08c9d56849ae86d7d2d2227f889a
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32444- (2024)
Pogostemon cablin (PC) is a traditional Chinese medicine (TCM) and food as well as an important essential oil plant in China. PC essential oil exerts pharmacological effects such as anti-inflammatory, anti-oxidant, anti-platelet, anti-thrombotic, and
Externí odkaz:
https://doaj.org/article/1cc588a2bd274b298360a638a4adabb1
Autor:
Yameng Zhu, Huizi Ouyang, Zhenguo Lv, Guangzhe Yao, Minglei Ge, Xiunan Cao, Yanxu Chang, Jun He
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction:Pogostemon cablin (PC) is used in traditional Chinese medicine and food, as it exerts pharmacological effects, such as immune-modulatory, antibacterial, antioxidant, antitumor, and antiviral. Currently, the pharmacokinetics (PK) studies
Externí odkaz:
https://doaj.org/article/d87b38d030fb48518b04adfa3cb0ece6
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 4, Pp 105664- (2024)
Physochlainae Radix (PR) is generally applied for treating cough and asthma. In this study, a sensitive ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UHPLC-MS/MS) method was established and validated f
Externí odkaz:
https://doaj.org/article/be8fb4c62a41404cbcef53c9e9a67d1b
Akademický článek
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Autor:
Leandro Tasso, Thamyrys Barreto Argenta, Beatriz Ferreira de Carvalho Patricio, Helvécio Vinícius Antunes Rocha
Publikováno v:
Drug Analytical Research, Vol 7, Iss 2 (2024)
This article aims to analyze the development of a rapid and sensitive HPLC–MS/MS method for quantification of efavirenz in rat plasma. The developed method included a liquid-liquid extraction process with methyl-tert-butyl ether solution, where hyd
Externí odkaz:
https://doaj.org/article/57f5904f02834c2f809fd9b417f5d44e
Autor:
Abdulaziz Alnasser, Mohamed Hefnawy, Mohammed Alanazi, Abdullah Al-Hossaini, Yousef Bin Jardan, Adel El-Azab, Alaa Abdel-Aziz, Mohamed Attwa, Manal El-Gendy
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 10, Pp 105117- (2023)
Acute myeloid leukemia (AML) is characteristic by high concentrations of immature bone marrow myeloid cells. Glasdegib (DaurismoTM, GSB) in combination with low dose cytarabin (DepocytTM, CTB) have recently been approved by the US Food and Drug Admin
Externí odkaz:
https://doaj.org/article/42bdba528e854c3a9479fb50074a78a8
Publikováno v:
Separations, Vol 11, Iss 2, p 55 (2024)
Perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is registered for the adjunctive treatment of patients (aged ≥ 12 years) with refractory partial-onset seizures. A simple high-performance liquid
Externí odkaz:
https://doaj.org/article/7adad89159eb44d8889069cb07bcbd03
Autor:
Abdulaziz I. Alnasser, Mohamed M. Hefnawy, Abdullah M. Al-Hossaini, Yousef A. Bin Jardan, Adel S. El-Azab, Alaa M. Abdel-Aziz, Abdulrahman M. Al-Obaid, Ibrahim A. Al-Suwaidan, Mohamed W. Attwa, Manal A. El-Gendy
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 9, Pp 101693- (2023)
This study developed a novel, sensitive and selective LC-MS/MS method for the concurrent determination of DCB and VTX in rat plasma using encorafenib as internal standard (IS). To identify DCB, VTX, and IS, the positive multiple reaction monitoring (
Externí odkaz:
https://doaj.org/article/cc770f7b22b14d4b83f8f2adb865c09a
Autor:
Shirong Cao, Yanhua Fu, Bingtong Jiang, Xueli Ge, Qi Wu, Yufan Tao, Pengfei Zhao, Zhaokun Wang
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 8, Pp 104942- (2023)
Loxoprofen sodium (LOX) is a propionic acid derivative non-steroidal anti-inflammatory drug (NSAID), existing in the form of four stereoisomers. The main metabolites of LOX in vivo were trans- and cis-alcohol, each consisting of four stereoisomers. T
Externí odkaz:
https://doaj.org/article/c9f2a3b2d51744d692cc835972180a62