Modern and prebiotic amino acids support distinct structural profiles in proteins

Autor: Vyacheslav Tretyachenko, Jiří Vymětal, Tereza Neuwirthová, Jiří Vondrášek, Kosuke Fujishima, Klára Hlouchová

Publikováno v: Open Biology, Vol 12, Iss 6 (2022)

The earliest proteins had to rely on amino acids available on early Earth before the biosynthetic pathways for more complex amino acids evolved. In extant proteins, a significant fraction of the ‘late’ amino acids (such as Arg, Lys, His, Cys, Trp

Externí odkaz: https://doaj.org/article/ebcdbbd8b3e748d3bbb6f2d971278c54

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Open questions in origin of life: experimental studies on the origin of nucleic acids and proteins with specific and functional sequences by a chemical synthetic biology approach

Autor: Pier Luigi Luisi, Fabrizio Anella, Rafal Wieczorek, Katarzyna P. Adamala, Cristiano Chiarabelli, Pasquale Stano

Publikováno v: Computational and Structural Biotechnology Journal, 9 (14), 2014
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 9, Iss 14, Pp 1-10 (2014)
Adamala, K, Anella, F, Wieczorek, R, Stano, P, Chiarabelli, C & Luisi, P L 2014, ' Open questions in origin of life: experimental studies on the origin of nucleic acids and proteins with specific and functional sequences by a chemical synthetic biology approach ', Computational and Structural Biotechnology Journal, vol. 9, no. 14, e201402004 . https://doi.org/10.5936/csbj.201402004

In this mini-review we present some experimental approaches to the important issue in the origin of life, namely the origin of nucleic acids and proteins with specific and functional sequences. The formation of macromolecules on prebiotic Earth faces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f6643dfdca25018771482dac449af
https://hdl.handle.net/11590/134125

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