Zobrazeno 1 - 10
of 129
pro vyhledávání: '"radiosensitiser"'
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105211- (2024)
Summary: Background: External radiation therapy (RT) is often a primary treatment for inoperable meningiomas in the absence of established chemotherapy. Histone deacetylase 6 (HDAC6) overexpression, commonly found in cancer, is acknowledged as a driv
Externí odkaz:
https://doaj.org/article/085249c400cb49ff9adf9eaf4cc660d8
Publikováno v:
IET Nanobiotechnology, Vol 17, Iss 3, Pp 212-223 (2023)
Abstract Melanoma is a dangerous type of skin cancer sometimes treated with radiotherapy. However, it induces damage to the surrounding healthy tissue and possibly further away areas. Therefore, it is necessary to give a lower dose to the patient wit
Externí odkaz:
https://doaj.org/article/40d2d7aba2374ad3a3a573738e4cc523
Autor:
Pouya Dehghankelishadi, Parisa Badiee, Michelle F. Maritz, Nicole Dmochowska, Benjamin Thierry
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Disruption of the cell cycle is among the most effective approach to increase tumour cells’ radio-sensitivity. However, the presence of dose-limiting side effects hampers the clinical use of tyrosine kinase inhibitors targeting the cell cy
Externí odkaz:
https://doaj.org/article/51f5b8e9204d4e19818a825bf718c9ac
Autor:
Shushu Xue, Junrong Jiao, Si Miao, Lijun Wang, Yang Liu, Qingjie Zhang, Qiyue Wang, Yu Xi, Yuanyuan Zhang
Publikováno v:
IET Nanobiotechnology, Vol 16, Iss 9, Pp 305-315 (2022)
Abstract Lung metastatic breast cancer (LMBC) leads to a large number of deaths in women with breast cancer, and radiotherapy has been considered the common assay for tumour therapy except for surgery. However, radiotherapy still faces problems of lo
Externí odkaz:
https://doaj.org/article/119b78baa98e47f48a04a99acf503462
Autor:
Croí E. Buckley, Rebecca M. O’Brien, Timothy S. Nugent, Noel E. Donlon, Fiona O’Connell, John V. Reynolds, Adnan Hafeez, Diarmuid S. O’Ríordáin, Robert A. Hannon, Paul Neary, Reza Kalbassi, Brian J. Mehigan, Paul H. McCormick, Cara Dunne, Michael E. Kelly, John O. Larkin, Jacintha O’Sullivan, Niamh Lynam-Lennon
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Resistance to neoadjuvant chemoradiation therapy, is a major challenge in the management of rectal cancer. Increasing evidence supports a role for altered energy metabolism in the resistance of tumours to anti-cancer therapy, suggesting that targetin
Externí odkaz:
https://doaj.org/article/3e43e6fdd76b4196a34b0a99aec3c412
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 40, Iss , Pp 100614- (2023)
Background and purpose: Radical concurrent chemoradiotherapy (CRT) for oesophageal cancer is associated with significant morbidity and is unsuitable for some patients. Olaparib, an inhibitor of the DNA repair enzyme poly-(ADP)-ribose polymerase (PARP
Externí odkaz:
https://doaj.org/article/cf4a84c75990477593f9349e5ae34015
Akademický článek
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Autor:
Shahin Sarowar, Davide Cirillo, Pablo Játiva, Mette Hartmark Nilsen, Sarah-Muheha Anni Otragane, Jan Heggdal, Frode Selheim, Valentín Ceña, Hans-René Bjørsvik, Per Øyvind Enger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metastatic tumors with moderate radiosensitivity account for most cancer-related deaths, highlighting the limitations of current radiotherapy regimens. The xCT-inhibitor sulfasalazine (SAS) sensitizes cancer cells to radiotherapy by blocking cystine
Externí odkaz:
https://doaj.org/article/dd9a9a4b0be142ba87cf11186be1469d
Publikováno v:
Cancer Nanotechnology, Vol 10, Iss 1, Pp 1-20 (2019)
Abstract Background A wide range of nanoparticles (NPs), composed of different elements and their compounds, are being developed by several groups as possible radiosensitisers, with some already in clinical trials. However, no systematic experimental
Externí odkaz:
https://doaj.org/article/2d2f07ae9b794035839dfaac03a4a7f2
Akademický článek
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