Zobrazeno 1 - 10
of 12 884
pro vyhledávání: '"radioresistance"'
Autor:
Zheng Lei, Jiang He, Haonan Yang, Lu Zhang, Tangmin Lai, Liu Zhou, Zheng Tang, Jiangdong Sui, Yongzhong Wu
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Radioresistance contributes to metastasis and recurrence in non-small cell lung cancer (NSCLC) patients. However, the underlying mechanism remains unclear. To provide novel clues, a complete multi-omics map of a radioresistant cancer cell li
Externí odkaz:
https://doaj.org/article/584f8fe95f594d409c38f32756372d43
Autor:
Carolina Oliva, Diego Carrillo-Beltrán, Julio C. Osorio, Iván Gallegos, Felipe Carvajal, Claudio Mancilla-Miranda, Paul Boettiger, Enrique Boccardo, Francisco Aguayo
Publikováno v:
Infectious Agents and Cancer, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background High-risk human papillomaviruses are the causal agents of a subset of head and neck cancers. A previous transcriptomic analysis showed that cIAP2 protein, involved in cell survival and apoptosis, is upregulated in OKF6 oral cells
Externí odkaz:
https://doaj.org/article/7ea0dcc5de4d462cadf7280be93b89b5
Autor:
Yizhe Gao, Qingjie Liu
Publikováno v:
Radiation Medicine and Protection, Vol 5, Iss 3, Pp 165-169 (2024)
Bioinformatics has become increasingly integral to radiation biology, also known as radiobiology, providing substantial support through data storage, conversion, visualization, and sharing. This review aims to deepen understanding of bioinformatics a
Externí odkaz:
https://doaj.org/article/9fef3629aafc4b4ea7cee0ac277e44ed
Autor:
Jialing Zhang, Zhaoyan Jiang, Xinglong Liu, Xiaoya Jin, Yan Pan, Yang Bai, Jianghong Zhang, Chunlin Shao
Publikováno v:
Radiation Medicine and Protection, Vol 5, Iss 3, Pp 178-184 (2024)
Objective: To investigate the potential role of the regulator of G protein signaling 20 (RGS20) in radioresistance of non-small cell lung cancer (NSCLC). Methods: A total of 35 lung adenocarcinoma (LUAD) patients from The Cancer Genome Atlas (TCGA),
Externí odkaz:
https://doaj.org/article/bd90a7ed8e1a499ab05e1633e4f77b71
Publikováno v:
International Journal of Translational Medicine, Vol 4, Iss 3, Pp 463-485 (2024)
Cancer stem cells (CSCs) are a dynamic population of tumor cells characterized by long-term self-renewal, high tumorigenicity, resistance to conventional therapies such as radio- and chemotherapy, and capacity to recapitulate the tumor heterogeneity.
Externí odkaz:
https://doaj.org/article/c543fd1b0a9244c2833f121d2c08fba8
Autor:
Hui Qiu, Zhiying Shao, Xin Wen, Debao Qu, Zhengyang Liu, Ziqin Chen, Xinyan Zhang, Xin Ding, Longzhen Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Radioresistance and immune escape are crucial reasons for unsatisfactory therapeutic effects of glioblastoma (GBM). Although triggering receptor expressed on myeloid cells-2 (TREM2) involved in forming immunosuppressive microenvir
Externí odkaz:
https://doaj.org/article/ffc87da269e343c58f8c0d16862670bf
Autor:
Min Yu, Mengdong Ni, Fei Xu, Chaohua Liu, Lihua Chen, Jiana Li, Siyu Xia, Yixin Diao, Jiaxin Chen, Jun Zhu, Xiaohua Wu, Min Tang, Jiajia Li, Guihao Ke
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Radioresistance is the leading cause of death in advanced cervical cancer (CC). Dysregulation of RNA modification has recently emerged as a regulatory mechanism in radiation and drug resistance. We aimed to explore the biological
Externí odkaz:
https://doaj.org/article/c0f1c6f1a0cb48519f5c584479f737bf
Autor:
Jianming Tang, Jing Li, Jiayan Lian, Yumei Huang, Yaqing Zhang, Yanwei Lu, Guansheng Zhong, Yaqi Wang, Zhitao Zhang, Xin Bai, Min Fang, Luming Wu, Haofei Shen, Jingyuan Wu, Yiqing Wang, Lei Zhang, Haibo Zhang
Publikováno v:
Journal of Advanced Research, Vol 61, Iss , Pp 239-251 (2024)
Introduction: Despite radiotherapy being one of the major treatments for triple-negative breast cancer (TNBC), new molecular targets for its treatment are still required due to radioresistance. CDK2 plays a critical role in TNBC. However, the mechani
Externí odkaz:
https://doaj.org/article/699eb4bf73654c89be43d53085bad4de
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Intracranial metastatic disease is a serious complication of cancer, treated through surgery, radiation, and targeted therapies. The central role of radiation therapy makes understanding the radioresistance of metastases a priori a key interest for p
Externí odkaz:
https://doaj.org/article/983bdd15c0a944edba456e5dfb0a6680
Autor:
Xiaobo Shi, Xiaozhi Zhang, Xinran Huang, Ruijuan Zhang, Shupei Pan, Shan Huang, Yuchen Wang, Yue Ke, Wei Guo, Xiaoxiao Liu, Yu Hao, You Li, Xu Zhao, Yuchen Sun, Jing Li, Hongbing Ma, Xixi Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Radiotherapy is a primary therapeutic modality for esophageal squamous cell carcinoma (ESCC), but its effectiveness is still restricted due to the resistance of cancer cells to radiation. Long non‐coding RNAs (lncRNAs) and N6‐
Externí odkaz:
https://doaj.org/article/859a1c5877ce4f388c3cb412a72c4fc9