Radiotherapy-activated NBTXR3 nanoparticles modulate cancer cell immunogenicity and TCR repertoire

Autor: Audrey Darmon, Ping Zhang, Julie Marill, Naeemunnisa Mohamed Anesary, Jordan Da silva, Sébastien Paris

Publikováno v: Cancer Cell International, Vol 22, Iss 1, Pp 1-14 (2022)

Abstract Background Radiotherapy is a powerful and widely used technique for the treatment of solid tumors. Beyond its ability to destroy tumor cells, it has been demonstrated that radiotherapy can stimulate the anti-tumor immune response. Unfortunat

Externí odkaz: https://doaj.org/article/986dba09200c448f929805458b80d565

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NBTXR3 Radiotherapy-Activated Functionalized Hafnium Oxide Nanoparticles Show Efficient Antitumor Effects Across a Large Panel of Human Cancer Models

Autor: Zhang P, Marill J, Darmon A, Mohamed Anesary N, Lu B, Paris S

Publikováno v: International Journal of Nanomedicine, Vol Volume 16, Pp 2761-2773 (2021)

Ping Zhang,1 Julie Marill,1 Audrey Darmon,1 Naeemunnisa Mohamed Anesary,1 Bo Lu,2 Sébastien Paris1 1Nanobiotix, Paris, France; 2Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, 19107, USACorrespondence: Sébastien Par

Externí odkaz: https://doaj.org/article/f884981327a745a3b818c94e208a4da7

Combining Augmented Radiotherapy and Immunotherapy through a Nano-Gold and Bacterial Outer-Membrane Vesicle Complex for the Treatment of Glioblastoma

Autor: Mei-Hsiu Chen, Tse-Ying Liu, Yu-Chiao Chen, Ming-Hong Chen

Publikováno v: Nanomaterials, Vol 11, Iss 7, p 1661 (2021)

Glioblastoma, formerly known as glioblastoma multiforme (GBM), is refractory to existing adjuvant chemotherapy and radiotherapy. We successfully synthesized a complex, Au–OMV, with two specific nanoparticles: gold nanoparticles (AuNPs) and outer-me

Externí odkaz: https://doaj.org/article/17adbbfb9cc74800a5bc1bb83e60b7a3

Metallic Nanoparticles: A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy?

Autor: Julien L. Colaux, Félicien Hespeels, Sébastien Penninckx, Anne-Catherine Heuskin, Stéphane Lucas, Julien Smeets

Publikováno v: Penninckx, S, Hespeels, F, Smeets, J, Colaux, J, Lucas, S & Heuskin, A-C 2021, ' Metallic Nanoparticles : A Useful Prompt Gamma Emitter for Range Monitoring in Proton Therapy? ', Radiation, vol. 1, no. 4, pp. 305-316 . https://doi.org/10.3390/radiation1040025
Radiation and Its Application in Oncology and Radiation Protection
Radiation; Volume 1; Issue 4; Pages: 305-316
Radiation, Vol 1, Iss 25, Pp 305-316 (2021)

In clinical practice, dose delivery in proton therapy treatment is affected by uncertainties related to the range of the beam in the patient, which requires medical physicists to introduce safety margins on the penetration depth of the beam. Although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ef88ea00de1dab0b33a30a796cf375
https://doi.org/10.3390/radiation1040025