A fast Monte Carlo cell-by-cell simulation for radiobiological effects in targeted radionuclide therapy using pre-calculated single-particle track standard DNA damage data

Autor: A. Lim, M. Andriotty, T. Yusufaly, G. Agasthya, B. Lee, C. Wang

Publikováno v: Frontiers in Nuclear Medicine, Vol 3 (2023)

IntroductionWe developed a new method that drastically speeds up radiobiological Monte Carlo radiation-track-structure (MC-RTS) calculations on a cell-by-cell basis.MethodsThe technique is based on random sampling and superposition of single-particle

Externí odkaz: https://doaj.org/article/f785249d40034d87a481fe008ea3766e

Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits

Autor: Ianik Plante, Floriane Poignant, Tony Slaba

Publikováno v: Life, Vol 11, Iss 11, p 1112 (2021)

To understand the biological effects of radiation, it is important to determine how ionizing radiation deposits energy in micrometric targets. The energy deposited in a target located in an irradiated tissue is a function of several factors such as t

Externí odkaz: https://doaj.org/article/bc7c3b6500cf4027887248a58326d3e3

A matter of space: How the spatial heterogeneity in energy deposition determines the biological outcome of radiation exposure

Autor: Baiocco, Giorgio, Bartzsch, Stefan, Conte, Valeria, Friedrich, Thomas, Jakob, Burkhard, Tartas, Adrianna, Villagrasa, Carmen, Prise, Kevin M.

Publikováno v: Radiat. Environ. Biophys. 61, 545-559 (2022)
Baiocco, G, Bartzsch, S, Conte, V, Friedrich, T, Jakob, B, Tartas, A, Villagrasa, C & Prise, K M 2022, ' A matter of space: how the spatial heterogeneity in energy deposition determines the biological outcome of radiation exposure ', Radiation and Environmental Biophysics, vol. 61, no. 4, pp. 545-559 . https://doi.org/10.1007/s00411-022-00989-z
Radiation and environmental biophysics 61(4), 545-559 (2022). doi:10.1007/s00411-022-00989-z

Radiation and environmental biophysics 61(4), 545 - 559 (2022). doi:10.1007/s00411-022-00989-z
Published by Springer, New York, NY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ee972dfb39200e9e5afb43ab51fc2b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66444

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