Zobrazeno 1 - 10
of 335
pro vyhledávání: '"rab10"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The objective of this study was to investigate the correlation between Rab10 (GTP binding protein RAB10), TLR4 (Toll-like receptor 4), and NF-κB (nuclear factor kappa-B) levels and therapeutic effects in peripheral blood of patients with br
Externí odkaz:
https://doaj.org/article/149e6f4f51a2498f8c94bd450a16f834
Autor:
Zhuoxuan Yu, Qiang Fu, Tianyun Qiu, Caidi Yang, Mingfen Lu, Qinghua Peng, Jianhua Yang, Zhenzhen Hu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
AimPrevious studies have demonstrated that Ras-related GTP-binding protein Rab10 (Rab10) plays a role in psychostimulant-induced behavioral effects. In this study, we showed that Rab10 in the nucleus accumbens (NAc) of male animals affects the develo
Externí odkaz:
https://doaj.org/article/aa5abf53398a49a38d81491cc3179d80
Autor:
Vera Ruíz Moleón, Carl Laflamme, Kathleen Southern, Riham Ayoubi, Charles Alende, Maryam Fotouhi
Publikováno v:
F1000Research, Vol 13 (2024)
Rab10 is a small GTPase involved in cargo transport from the trans-Golgi network to the plasma membrane and endocytic recycling back to the cell membrane. It has garnered significant interest in neurodegenerative disease research, particularly due to
Externí odkaz:
https://doaj.org/article/1d5d357aa8c649cc932c930a73d5ad07
Autor:
Vijay Singh, Marissa A. Menard, Geidy E. Serrano, Thomas G. Beach, Hien T. Zhao, Alexis Riley-DiPaolo, Nitya Subrahmanian, Matthew J. LaVoie, Laura A. Volpicelli-Daley
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Autosomal dominant pathogenic mutations in Leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease (PD). The most common mutation, G2019S-LRRK2, increases the kinase activity of LRRK2 causing hyper-phosphorylation of its substrates.
Externí odkaz:
https://doaj.org/article/32aba7e8d1c24bdfa405421b9f329790
Publikováno v:
eLife, Vol 12 (2024)
Rab GTPases are representative targets of manipulation by intracellular bacterial pathogens for hijacking membrane trafficking. Legionella pneumophila recruits many Rab GTPases to its vacuole and exploits their activities. Here, we found that infecti
Externí odkaz:
https://doaj.org/article/dc58dac948a14e369dbf50d4b75fb61b
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 431-440 (2022)
Background : Acute myeloid leukemia (AML) is regarded as a haematological malignancy and seriously threatens the public’s health. Circular RNA (circRNA) is gradually confirmed to be involved in the development of AML. The purpose of this study was
Externí odkaz:
https://doaj.org/article/37b245193d2c4162a9f18f26d9608bc5
Autor:
Lynne A. Lapierre, Joseph T. Roland, Elizabeth H. Manning, Catherine Caldwell, Honor L. Glenn, Pierre-Olivier Vidalain, Frederic Tangy, Brenda G. Hogue, C. A. M. de Haan, James R. Goldenring
Publikováno v:
Cells, Vol 13, Iss 2, p 126 (2024)
The membrane (M) glycoprotein of coronaviruses (CoVs) serves as the nidus for virion assembly. Using a yeast two-hybrid screen, we identified the interaction of the cytosolic tail of Murine Hepatitis Virus (MHV-CoV) M protein with Myosin Vb (MYO5B),
Externí odkaz:
https://doaj.org/article/56936c737ca2422085995578d9e59d30
Akademický článek
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Autor:
Yanhui Li, Yue Xiong, Zhen Wang, Jianjun Han, Sufang Shi, Jinglan He, Na Shen, Wenjuan Wu, Rui Wang, Weiwei Lv, Yajun Deng, Weiguang Liu
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-20 (2021)
Abstract Background Breast cancer (BC) is one of the most common cancers and the leading cause of death in women. Previous studies have demonstrated that FAM49B is implicated in several tumor progression, however, the role and mechanism of FAM49B in
Externí odkaz:
https://doaj.org/article/57837eb55403453ba23af104a0692c83
Akademický článek
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