Zobrazeno 1 - 10 of 27 pro vyhledávání: '"rMnSOD"'
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Effect of rMnSOD on Sodium Reabsorption in Renal Proximal Tubule in Ochratoxin A—Treated Rats
Autor: Enrica Zona, Sara Damiano, Luigi Avallone, Aldo Mancini, Silvia Boffo, Antonio Giordano, Carlo Astarita, Antonella Borrelli, Caterina Squillacioti, Maria Valeria Puzio, Salvatore Florio, Roberto Ciarcia, Nicola Mirabella
Publikováno v: Journal of Cellular Biochemistry. 119:424-430
Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium that represent toxic real threat for human beings and animal health. In this study we evaluated the effect of a new recombinant mitochondrial manganese containing superoxide di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bb3d65b17d3a801c20b23908d3bf10
https://doi.org/10.1002/jcb.26197
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3
Enhancer Role of rMnSOD in apoptosis triggering by daunorubicin of pediatric B-ALL cells
Autor: Casale, F., D’Angelo, V., PICA, ALESSANDRA, Iannotta, A., Ramaglia, M., Di Massa, L., POLLIO, MARIA LAURA, MANCA, ROSA, Di Martino, M., Oreste, M., Mancini, A, Borrelli, A, Indolfi, P.
Background/Objectives Leukemic cells produce higher amounts of ROS than healthy cells and express low levels of antioxidant enzymes such as catalase (CAT) and superoxide dismutase (SOD). Recently, it was demonstrated that rMnSOD, a recombinant new is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::68d0ec65aa1df2818710b45f7dbf4a0e
http://hdl.handle.net/11588/678192
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4
Effects of a New Human Recombinant MnSOD in the Treatment of Photoaging and Actinic Keratosis
Autor: Aldo Mancini, Antonietta Schiattarella, Maria Grazia Ruggiero, Maria Laura Pollio, Antonella Borrelli, Patrizia Forgione, Alessandra Pica
Publikováno v: Journal of Cancer Therapy. :56-59
Physiological processes, as aerobic metabolism and inflammatory response, generate reactive oxygen species (ROS) that may induce cellular injury when their amount is increased and antioxidant defense mechanisms are overwhelmed. Also, ROS are generate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7e81a871db84b5f6342dd86e9775d3
https://doi.org/10.4236/jct.2013.46a1009
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5
Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent
Autor: Piero Pucci, Ettore Novellino, Antonella Schiattarella, Lelio Mazzarella, Filomena Sica, Paolo Grieco, Jean Rommelaere, R. Lorizio, Alessandro Sica, Franco Morelli, Roberto Mancini, Antonella Borrelli, Antonella Occhiello, Luigi Aloj, Michela Aurilio, Aldo Mancini, Daniela Pagnozzi, Alessandra Pica
Publikováno v: International journal of cancer
123 (2008): 2684–2695. doi:10.1002/ijc.23791
info:cnr-pdr/source/autori:Mancini A.; Borrelli A.; Schiattarella A.; Aloj L.; Aurilio M.; Morelli F.; Pica A.; Occhiello A.; Lorizio R.; Mancini R.; Sica A.; Mazzarella L.; Sica F.; Grieco P.; Novellino E.; Pagnozzi D.; Pucci P. and Rommelaere J./titolo:Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent/doi:10.1002%2Fijc.23791/rivista:International journal of cancer (Print)/anno:2008/pagina_da:2684/pagina_a:2695/intervallo_pagine:2684–2695/volume:123
A recombinant MnSOD (rMnSOD) synthesized by specific cDNA clones derived from a liposarcoma cell line was shown to have the same sequence as the wild-type MnSOD expressed in the human myeloid leukaemia cell line U937, except for the presence of the l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8670eec5ec14b202c905d1567f8d1c09
https://doi.org/10.1002/ijc.23791
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7
Role of rMnSOD as Cytotoxic Agent and Chemotherapy Enhancer in Paediatric Acute Lymphoblastic Leukemia B Cells
Autor: F. Casale, V. D’Angelo, A. Iannotta, M. Ramaglia, M. L. Pollio, M. G. Ruggiero, A. Borrelli, D. Di Pinto, M. Oreste, A. Mancini, PICA, ALESSANDRA
Background/Objectives: An isoform of Manganese-superoxide-dismutase (rMnSOD) was isolated and sequenced for the first time from a human Liposarcoma cells and obtained in recombinant form. The protein showed a specific and selective cytotoxicity on ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::72b433d83fcb281c11e8813607f010ba
http://hdl.handle.net/11588/678363
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8
Effect of rMnSOD on survival signaling in pediatric high risk T-cell acute lymphoblastic leukaemia
Autor: Pica, A, Di Santi, A, D'ANGELO, Velia, Iannotta, A, Ramaglia, M, Di Martino, M, Pollio, M. L, Schiattarella, A, Borrelli, A, Mancini, A, INDOLFI, Paolo, CASALE, Fiorina
Publikováno v: Journal of cellular physiology. 230(5)
Manganese superoxide dismutase (MnSOD) is a mitochondrial enzyme that defends against oxidative damage due to reactive oxygen species (ROS). A new isoform of MnSOD with cytotoxic activity was recently discovered in liposarcoma cells. Here, we tested
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::75285d8048743609233c0b05c0433f62
https://pubmed.ncbi.nlm.nih.gov/25294747
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9
Increase in post-thaw viability of cord blood HSC by adding rMnSOD: preliminary results
Autor: Ruggiero M.G., Pollio M.L., Toriello M., Borrelli A., Schiattarella A., Mancini A., Poggi V., PICA, ALESSANDRA
Umbilical cord blood (UCB) represents a source for hematopoietic stem cells (CB-HSC), and transplantation of cord blood has been part of clinical practice since more than 10 years (Lee et al., Blood 103, 2004). The UCB is usually collected by public
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::521c3f18a7c719a57be66de03b9ef49f
http://hdl.handle.net/11588/593788
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