Zobrazeno 1 - 7
of 7
pro vyhledávání: '"r.t., room temperature"'
Autor:
Jia Meng, Yan Zhao, Guangying Shao, Shun Zhang, Zemei Ge, Baoxue Yang, Xiaoqiang Geng, Shuyuan Wang, Yue Xu, Min Li, Jinzhao He, Runtao Li, Guangping Chen, Hong Zhou, Jianhua Ran
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 181-202 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Urea transporters (UT) play a vital role in the mechanism of urine concentration and are recognized as novel targets for the development of salt-sparing diuretics. Thus, UT inhibitors are promising for development as novel diuretics. In the present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07691ffc571a4d2e747924feb8f8ea3
https://doi.org/10.1016/j.apsb.2020.06.001
https://doi.org/10.1016/j.apsb.2020.06.001
Autor:
Xin-Hui Zhang, Hong-Min Liu, Yongfang Yao, Li-Ying Ma, Xue-Jian Feng, Qin Shangshang, Tingting Yu, Bing Zhao, De-Quan Yu, Xiaoling Zhang, Ying Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 203-221 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44e2471539ae24953ab00f10282f4be
http://www.sciencedirect.com/science/article/pii/S2211383520306316
http://www.sciencedirect.com/science/article/pii/S2211383520306316
Autor:
Xiangyu Zhang, Chunxiu Wu, Sheng Jiang, Youhua Xie, Ji Zhang, Jinbiao Liao, Yong Ni, Zhenlong Qian
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
Since the end of 2019, the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic. There is an urgent need for effective and low-toxic antiviral drugs to remedy Remdesivir
Since the end of 2019, the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic. There is an urgent need for effective and low-toxic antiviral drugs to remedy Remdesivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc3fb8e6e00ed1e353da0d6395b3825
http://europepmc.org/articles/PMC8606320
http://europepmc.org/articles/PMC8606320
Autor:
Amgad M. Rabie
Publikováno v:
MethodsX
MethodsX, Vol 7, Iss, Pp 100737-(2020)
MethodsX, Vol 7, Iss, Pp 100737-(2020)
Graphical abstract
The usefulness of the structure of galloyl hydrazide (3,4,5-trihydroxybenzohydrazide, coded as 2nz in this article) as a privileged structural system in pharmaceutical organic and medicinal chemistry has prompted the advances
The usefulness of the structure of galloyl hydrazide (3,4,5-trihydroxybenzohydrazide, coded as 2nz in this article) as a privileged structural system in pharmaceutical organic and medicinal chemistry has prompted the advances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8685895691847c8c96ab4b4d55c4b833
https://doi.org/10.1016/j.mex.2019.11.010
https://doi.org/10.1016/j.mex.2019.11.010
Autor:
Zhang S; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Zhao Y; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.; College of Pharmacy, Inner Mongolia Medical University, Hohhot 010110, China., Wang S; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Li M; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Xu Y; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Ran J; Department of Anatomy and Neuroscience Center, Chongqing Medical University, Chongqing 400016, China., Geng X; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China., He J; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Meng J; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Shao G; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Zhou H; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China., Ge Z; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Chen G; Department of Physiology, Emory University School of Medicine, Atlanta, GA 30322, USA., Li R; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China., Yang B; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Jan; Vol. 11 (1), pp. 181-202. Date of Electronic Publication: 2020 Jun 14.
Autor:
Zhao B; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Zhang X; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Yu T; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu Y; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Zhang X; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Yao Y; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Feng X; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Liu H; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Yu D; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China., Ma L; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Qin S; State Key Laboratory of Esophageal Cancer Prevention and Treament, Key Laboratory of Technology of Drug Preparation (Zhengzhou University), Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Jan; Vol. 11 (1), pp. 203-221. Date of Electronic Publication: 2020 Jul 16.
Autor:
Rabie AM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Publikováno v:
MethodsX [MethodsX] 2019 Nov 15; Vol. 7, pp. 100737. Date of Electronic Publication: 2019 Nov 15 (Print Publication: 2020).