Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field

Autor: Andrew Hammond 1, 2, 9, Paola Pollegioni 3, 4, Tania Persampieri3, Ace North 5, Roxana Minuz3, Alessandro Trusso3, Alessandro Bucci3, Kyros Kyrou 1, Ioanna Morianou1, Alekos Simoni1, 3, Tony Nolan 1, 6, 10?, Ruth Müller 3, 7, 8, Andrea Crisanti1

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature communications 12 (2021). doi:10.1038/s41467-021-24790-6
info:cnr-pdr/source/autori:Andrew Hammond 1,2,9, Paola Pollegioni 3,4,9, Tania Persampieri3,9, Ace North 5, Roxana Minuz3, Alessandro Trusso3, Alessandro Bucci3, Kyros Kyrou 1, Ioanna Morianou1, Alekos Simoni1,3, Tony Nolan 1,6,10?, Ruth Müller 3,7,8,10? & Andrea Crisanti1,10?/titolo:Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field/doi:10.1038%2Fs41467-021-24790-6/rivista:Nature communications/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:12

CRISPR-based gene-drives targeting the gene doublesex in the malaria vector Anopheles gambiae effectively suppressed the reproductive capability of mosquito populations reared in small laboratory cages. To bridge the gap between laboratory and the fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf5bfcdc2558f0000d6533c07c7d398
https://doaj.org/article/28f129b4a117412cbbe999b2ef1b9abf

Symbionts and gene drive: two strategies to combat vector-borne disease

Autor: Guan-Hong Wang, Jie Du, Chen Yi Chu, Mukund Madhav, Grant L. Hughes, Jackson Champer

Mosquitoes bring global health problems by transmitting parasites and viruses such as malaria and dengue. Unfortunately, current insecticide-based control strategies are only moderately effective because of high cost and resistance. Thus, scalable, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cdad9723da2e674e5ee79d790e977c
https://archive.lstmed.ac.uk/20152/1/PIIS0168952522000403.pdf

Reviewing the WHO Tube Bioassay Methodology: Accurate Method Reporting and Numbers of Mosquitoes Are Key to Producing Robust Results

Autor: Giorgio Praulins, Daniel P. McDermott, Angus Spiers, Rosemary Susan Lees

Publikováno v: Insects; Volume 13; Issue 6; Pages: 544

Accurately monitoring insecticide resistance in target mosquito populations is important for combating malaria and other vector-borne diseases, and robust methods are key. The “WHO susceptibility bioassay” has been available from the World Health

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7a08edf1ee6f66fb34fb0b51993bdc

High insecticide resistance mediated by different mechanisms in Culex quinquefasciatus populations from the city of Yaoundé, Cameroon

Autor: Sévilor Kekeunou, Christophe Antonio-Nkondjio, Roland Bamou, Charles S. Wondji, Borel Djiappi-Tchamen, Abdou Talipouo, John Vontas, Parfait Awono-Ambene, Sofia Balaska, Edmond Kopya, Emmanouil A. Fotakis, Vasileia Balabanidou, Konstantinos Mavridis, Elysee Nchoutpouen

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

Culex mosquitoes particularly Culex quinquefasciatus are important arboviral and filariasis vectors, however despite this important epidemiological role, there is still a paucity of data on their bionomics. The present study was undertaken to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d039a8f6252bf35c4db402c726117aeb
https://doaj.org/article/ed838575707b4d94bb9bdc7922c1f8d2

Exposure of primate reservoir hosts to mosquito vectors in Malaysian Borneo

Autor: Brown, Rebecca, Salgado-Lynn, Milena, Jumail, Amaziasizamoria, Jalius, Cyrlen, Chua, Tock-Hing, Vythilingam, Indra, Ferguson, Heather M.

Several vector-borne pathogens of primates have potential for human spillover. An example is the simian malaria Plasmodium knowlesi which is now a major public health problem in Malaysia. Characterization of exposure to mosquito vectors is essential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2e61825db05e813300e1f3585d9860