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pro vyhledávání: '"qu_475"'
Mosquitoes bring global health problems by transmitting parasites and viruses such as malaria and dengue. Unfortunately, current insecticide-based control strategies are only moderately effective because of high cost and resistance. Thus, scalable, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cdad9723da2e674e5ee79d790e977c
https://archive.lstmed.ac.uk/20152/1/PIIS0168952522000403.pdf
https://archive.lstmed.ac.uk/20152/1/PIIS0168952522000403.pdf
Autor:
Robert S. Heyderman, Jillian S Gauld, Nicholas A. Feasey, Jane Mallewa, Sithembile Bilima, Peter J. Diggle, Nicholas R. Thomson, Franziska Olgemoeller, Alexander M. Wailan, Neil Kennedy, Jonathan M Read, Melita A. Gordon, Eva Heinz, Rose Nkhata
Publikováno v:
Gauld, J S, Olgemoeller, F, Heinz, E, Nkhata, R, Bilima, S, Wailan, A M, Kennedy, N, Mallewa, J, Gordon, M A, Read, J M, Heyderman, R S, Thomson, N R, Diggle, P J & Feasey, N A 2022, ' Spatial and genomic data to characterize endemic typhoid transmission ', Clinical Infectious Diseases, vol. 74, no. 11 . https://doi.org/10.1093/cid/ciab745
Background Diverse environmental exposures and risk factors have been implicated in the transmission of Salmonella Typhi, but the dominant transmission pathways through the environment to susceptible humans remain unknown. Here, we use spatial, bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868528c1e5165e9a8d8dbbdb5452ee1a
https://pure.qub.ac.uk/en/publications/ac199bd2-7117-49e2-81a3-ccd51fb79c95
https://pure.qub.ac.uk/en/publications/ac199bd2-7117-49e2-81a3-ccd51fb79c95
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-14 (2021)
Epigenetics & Chromatin
Hearn, J, Plenderleith, F & Little, T J 2021, ' DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna ', Epigenetics and Chromatin, vol. 14, 4 . https://doi.org/10.1186/s13072-020-00379-z
Epigenetics & Chromatin
Hearn, J, Plenderleith, F & Little, T J 2021, ' DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna ', Epigenetics and Chromatin, vol. 14, 4 . https://doi.org/10.1186/s13072-020-00379-z
Background Patterns of methylation influence lifespan, but methylation and lifespan may also depend on diet, or differ between genotypes. Prior to this study, interactions between diet and genotype have not been explored together to determine their i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e502c3db33955dfa70c85e4804f6b2dc
https://doaj.org/article/6214930941d24a7aa3b9345496e19731
https://doaj.org/article/6214930941d24a7aa3b9345496e19731
Autor:
Joseph M. Lewis, Madalitso Mphasa, Rachel Banda, Mathew A. Beale, Jane Mallewa, Eva Heinz, Nicholas R. Thomson, Nicholas A. Feasey
Publikováno v:
MICROBIAL GENOMICS
Members of the Klebsiella pneumoniae species complex, particularly K. pneumoniae subsp. pneumoniae are antimicrobial resistance (AMR) associated pathogens of global importance, and polyvalent vaccines targeting Klebsiella O-antigens are in developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c9ae1d5ec6463dbdfda038a0cb8a47
https://doi.org/10.1099/mgen.0.000778
https://doi.org/10.1099/mgen.0.000778
Publikováno v:
Hearn, J, Clark, J, Wilson, P J & Little, T J 2020, ' Daphnia magna modifies its gene expression extensively in response to caloric restriction revealing a novel effect on haemoglobin isoform preference ', Molecular Ecology, vol. 29, no. 17, pp. 1-16 . https://doi.org/10.1111/mec.15557
Caloric restriction (CR) produces clear phenotypic effects within and between generations of the model crustacean Daphnia magna. We have previously established that micro RNAs and cytosine methylation change in response to CR in this organism, and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b8f15bd2ffaf06997af5b95dbe573
https://doi.org/10.1111/mec.15557
https://doi.org/10.1111/mec.15557
Autor:
Post, Yorick, Puschhof, Jens, Beumer, Joep, Kerkkamp, Harald M, de Bakker, Merijn A G, Slagboom, Julien, de Barbanson, Buys, Wevers, Nienke R, Spijkers, Xandor M, Olivier, Thomas, Kazandjian, Taline D, Ainsworth, Stuart, Iglesias, Carmen Lopez, van de Wetering, Willine J, Heinz, Maria C, van Ineveld, Ravian L, van Kleef, Regina G D M, Begthel, Harry, Korving, Jeroen, Bar-Ephraim, Yotam E, Getreuer, Walter, Rios, Anne C, Westerink, Remco H S, Snippert, Hugo J G, van Oudenaarden, Alexander, Peters, Peter J, Vonk, Freek J, Kool, Jeroen, Richardson, Michael K, Casewell, Nicholas R, Clevers, Hans, Landdegradatie en aardobservatie, One Health Toxicologie, dIRAS RA-1, Sub Developmental Biology, Dep Farmaceutische wetenschappen, Developmental Biology
Publikováno v:
Cell, 180(2), 233-247.e21. Cell Press
Post, Y, Puschhof, J, Beumer, J, Kerkkamp, H M, de Bakker, M A G, Slagboom, J, de Barbanson, B, Wevers, N R, Spijkers, X M, Olivier, T, Kazandjian, T D, Ainsworth, S, Iglesias, C L, van de Wetering, W J, Heinz, M C, van Ineveld, R L, van Kleef, R G D M, Begthel, H, Korving, J, Bar-Ephraim, Y E, Getreuer, W, Rios, A C, Westerink, R H S, Snippert, H J G, van Oudenaarden, A, Peters, P J, Vonk, F J, Kool, J, Richardson, M K, Casewell, N R & Clevers, H 2020, ' Snake Venom Gland Organoids ', Cell, vol. 180, no. 2, pp. 233-247.e21 . https://doi.org/10.1016/j.cell.2019.11.038
Cell, 180(2), 233. Cell Press
Cell, 180(2), 233-247.e21. Elsevier B.V.
CELL, 180(2), 233-247. CELL PRESS
Post, Y, Puschhof, J, Beumer, J, Kerkkamp, H M, de Bakker, M A G, Slagboom, J, de Barbanson, B, Wevers, N R, Spijkers, X M, Olivier, T, Kazandjian, T D, Ainsworth, S, Iglesias, C L, van de Wetering, W J, Heinz, M C, van Ineveld, R L, van Kleef, R G D M, Begthel, H, Korving, J, Bar-Ephraim, Y E, Getreuer, W, Rios, A C, Westerink, R H S, Snippert, H J G, van Oudenaarden, A, Peters, P J, Vonk, F J, Kool, J, Richardson, M K, Casewell, N R & Clevers, H 2020, ' Snake Venom Gland Organoids ', Cell, vol. 180, no. 2, pp. 233-247.e21 . https://doi.org/10.1016/j.cell.2019.11.038
Cell, 180(2), 233. Cell Press
Cell, 180(2), 233-247.e21. Elsevier B.V.
CELL, 180(2), 233-247. CELL PRESS
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithelium. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf196fe1a6723ec147a5346143d623e9
https://doi.org/10.1016/j.cell.2019.11.038
https://doi.org/10.1016/j.cell.2019.11.038
Autor:
Jun-Yi Luo, Yi-Ning Yang, Xiao-Ming Gao, Guo-Li Du, Duolao Wang, Yan-Hong Li, Xiao-Mei Li, Bin-Bin Fang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Macrophage migration inhibitory factor (MIF) has been recognized as a major player in the pathogenesis of atherosclerosis. This study determined the association between polymorphisms of MIF gene and acute coronary syndrome (ACS). The polymorphism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c303a2e6054e2f2e03bad9ef6df13007
http://link.springer.com/article/10.1038/s41598-019-56949-z
http://link.springer.com/article/10.1038/s41598-019-56949-z
Autor:
Supathep Tansirichaiya, Richard N. Goodman, Xinyu Guo, Issra Bulgasim, Ørjan Samuelsen, Mohammed Al-Haroni, Adam P. Roberts
Mobile genetic elements (MGEs) are often associated with antimicrobial resistance genes (ARGs). They are responsible for intracellular transposition between different replicons and intercellular conjugation, and are therefore important agents of ARG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e93234b3258cb9ebff0502b49c92bf3
https://hdl.handle.net/10037/24711
https://hdl.handle.net/10037/24711
Autor:
Sahin-Tóth, Judit, Albert, Ervin, Juhász, Alexandra, Ghidán, Ágoston, Juhász, János, Horváth, Andrea, Steward, Martin C., Dobay, Orsolya
Publikováno v:
The Science of the total environment. 815
In 2011 mecC, a new mecA gene homologue, was described in a bovine isolate in the UK. Since then, mecC-positive methicillin-resistant Staphylococcus aureus (mecC-MRSA) has also been found in wild animals. An especially high prevalence of mecC-MRSA ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d669ca30f73b90c1b97952835f9c600
https://pubmed.ncbi.nlm.nih.gov/34995585
https://pubmed.ncbi.nlm.nih.gov/34995585
Publikováno v:
Insects
Volume 12
Issue 2
Insects, Vol 12, Iss 97, p 97 (2021)
Volume 12
Issue 2
Insects, Vol 12, Iss 97, p 97 (2021)
Simple Summary Malaria is a huge public health burden that affects predominantly sub-Saharan Africa and is transmitted by Anopheles mosquitoes. As a measure for population control, a method called gene drive has been recently developed, which relies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228f8029fc786251d20e73c29a01eafc