Zobrazeno 1 - 10
of 65
pro vyhledávání: '"qu_450"'
Autor:
Robert S. Heyderman, Jillian S Gauld, Nicholas A. Feasey, Jane Mallewa, Sithembile Bilima, Peter J. Diggle, Nicholas R. Thomson, Franziska Olgemoeller, Alexander M. Wailan, Neil Kennedy, Jonathan M Read, Melita A. Gordon, Eva Heinz, Rose Nkhata
Publikováno v:
Gauld, J S, Olgemoeller, F, Heinz, E, Nkhata, R, Bilima, S, Wailan, A M, Kennedy, N, Mallewa, J, Gordon, M A, Read, J M, Heyderman, R S, Thomson, N R, Diggle, P J & Feasey, N A 2022, ' Spatial and genomic data to characterize endemic typhoid transmission ', Clinical Infectious Diseases, vol. 74, no. 11 . https://doi.org/10.1093/cid/ciab745
Background Diverse environmental exposures and risk factors have been implicated in the transmission of Salmonella Typhi, but the dominant transmission pathways through the environment to susceptible humans remain unknown. Here, we use spatial, bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868528c1e5165e9a8d8dbbdb5452ee1a
https://pure.qub.ac.uk/en/publications/ac199bd2-7117-49e2-81a3-ccd51fb79c95
https://pure.qub.ac.uk/en/publications/ac199bd2-7117-49e2-81a3-ccd51fb79c95
Publikováno v:
Hearn, J, Clark, J, Wilson, P J & Little, T J 2020, ' Daphnia magna modifies its gene expression extensively in response to caloric restriction revealing a novel effect on haemoglobin isoform preference ', Molecular Ecology, vol. 29, no. 17, pp. 1-16 . https://doi.org/10.1111/mec.15557
Caloric restriction (CR) produces clear phenotypic effects within and between generations of the model crustacean Daphnia magna. We have previously established that micro RNAs and cytosine methylation change in response to CR in this organism, and we
Autor:
Yu-Ying Jiang, Weipeng Quan, Kenneth Wilson, Chao Wu, Wanqiang Qian, Bo Liu, Swapan Chakrabarty, Gilson Chipabika, Sheng-yuan Zhao, W. Zheng, Dandan Zhang, Wei Fan, Guirong Wang, Bei Liu, Jie Liu, Xinyue Liang, Amy Withers, Christopher M. Jones, Minghui Jin, Judith A. Smith, Yutao Xiao, Xiaolin Liu, Emmanuelle d'Alençon, Kiwoong Nam, Zaiyuan Li, Xianming Yang, Donald L. Kachigamba, Lei Zhang, Pengjun Xu, Conghui Liu, Kongming Wu
Publikováno v:
Molecular Ecology Resources
Molecular Ecology Resources, Wiley/Blackwell, 2020, ⟨10.1111/1755-0998.13219⟩
Molecular Ecology Resources, Wiley/Blackwell, 2020, ⟨10.1111/1755-0998.13219⟩
The rapid wide-scale spread of fall armyworm (Spodoptera frugiperda) has caused serious crop losses34 globally. However, differences in the genetic background of subpopulations and the mechanisms of rapid adaptation behind the invasion are still not
Autor:
Sage McKeand, Aniko Fazekas, Grant L. Hughes, Nijole Jasinskiene, Anthony A. James, Vanessa M. Macias, Duverney Chaverra-Rodriguez, Jason L. Rasgon, Sujit Pujhari
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1353-1360 (2020)
Innovative tool development is essential for continued advancement in malaria control and depends on a deeper understanding of the molecular mechanisms that govern transmission of malaria parasites by Anopheles mosquitoes. Targeted disruption of gene
Autor:
Neil D. Young, Andreas J. Stroehlein, Tao Wang, Pasi K. Korhonen, Margaret Mentink-Kane, J. Russell Stothard, David Rollinson, Robin B. Gasser
Publikováno v:
Nature Communications. 13
Some snails act as intermediate hosts (vectors) for parasitic flatworms (flukes) that cause neglected tropical diseases, such as schistosomiases. Schistosoma haematobium is a blood fluke that causes urogenital schistosomiasis and induces bladder canc
Autor:
Dewar, Caroline E., Casas Sanchez, Aitor, Dieme, Constentin, Crouzols, Aline, Haines, Lee, Acosta-Serrano, Alvaro, Rotureau, Brice, Schnaufer, Achim, Hajduk, Stephen L.
The single-celled parasite Trypanosoma brucei is transmitted by hematophagous tsetse flies. Life cycle progression from mammalian bloodstream form to tsetse midgut form and, subsequently, infective salivary gland form depends on complex developmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::99dba54e658754ece85a54afd2bf44a7
Autor:
Cecilia S. Lindestam Arlehamn, Bjoern Peters, Eneida A. Parizotto, Tom Fletcher, Matthew K. O'Shea, Akul Singhania, Timothy C. Rodwell, Helen McShane, Martin Dedicoat, Rachel Tanner, James Dunbar, Adam F. Cunningham, Julie G. Burel, Paige Dubelko, Antonino Catanzaro, Donald G. Catanzaro, Julius Muller
Publikováno v:
Tuberculosis (Edinb)
Although only a small fraction will ever develop the active form of tuberculosis (ATB) disease, chemoprophylaxis treatment in latent TB infected (LTBI) individuals is an effective strategy to control pathogen transmission. Characterizing immune respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e9a3fde36b496f7adf551953ba7b93
https://ora.ox.ac.uk/objects/uuid:fb9dfd7e-2ae9-4f45-9a69-bf854148eb4a
https://ora.ox.ac.uk/objects/uuid:fb9dfd7e-2ae9-4f45-9a69-bf854148eb4a
Autor:
Allan, Fiona K, Jayaraman, Siddharth, Paxton, Edith, Sindoya, Emmanuel, Kibona, Tito, Fyumagwa, Robert, Mramba, Furaha, Torr, Steve, Hemmink, Johanneke D, Toye, Philip, Lembo, Tiziana, Handel, Ian, Auty, Harriet K, Morrison, W Ivan, Morrison, Liam J
East Coast fever (ECF) in cattle is caused by the Apicomplexan protozoan parasite , transmitted by the three-host tick . The African buffalo () is the natural host for but does not suffer disease, whereas ECF is often fatal in cattle. The genetic rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c83e11f2e02ec0d3d9da16f9a3bb5f46
Autor:
Leann Tilley, Helen Jennings, Paul M. Griffin, Stephen Woolley, Anthony T. Papenfuss, Michelle J. Boyle, Fiona H. Amante, Jocelyn Sietsma Penington, Silvana Sekuloski, James S. McCarthy, Fabian de Labastida Rivera, Katharine R. Trenholme, Bridget E. Barber, Jo-Anne Chan, Emily M. Eriksson, Christian R. Engwerda, Anand Odedra, Michael F. Duffy, Dean Andrew, Alister Craig, Krystal J. Evans, Priyanka Sathe, Matthew W. A. Dixon, Julie Healer, Janet Storm, Rebecca Webster, Adam J. Blanch, Alan F. Cowman, Louis Schofield
Publikováno v:
BMC Medicine
BMC Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
BMC Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Background There is a clear need for novel approaches to malaria vaccine development. We aimed to develop a genetically attenuated blood-stage vaccine and test its safety, infectivity, and immunogenicity in healthy volunteers. Our approach was to tar
Autor:
Tony Nolan, Samantha M. O’Loughlin, Austin Burt, Andrea Crisanti, Silke Fuchs, Annie J Forster, Tania Dottorini
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
DNA sequences that are exactly conserved over long evolutionary time scales have been observed in a variety of taxa. Such sequences are likely under strong functional constraint and they have been useful in the field of comparative genomics for ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4677e85b4f80fa6d07cdbc21f912dd
https://archive.lstmed.ac.uk/17749/1/TN_oup.pdf
https://archive.lstmed.ac.uk/17749/1/TN_oup.pdf