Zobrazeno 1 - 10
of 26
pro vyhledávání: '"qu_4"'
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Tian Tian,1,* Xiaobo Zhang,1,* Tao Luo,1 Duolao Wang,2 Yuping Sun,3 Jianghong Dai1 1Department of Epidemiology and Biostatistics, School of Public Health, Xinjiang Medical University, Urumqi, 830001, Peopleâs Republic of China; 2Departme
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-14 (2021)
Epigenetics & Chromatin
Hearn, J, Plenderleith, F & Little, T J 2021, ' DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna ', Epigenetics and Chromatin, vol. 14, 4 . https://doi.org/10.1186/s13072-020-00379-z
Epigenetics & Chromatin
Hearn, J, Plenderleith, F & Little, T J 2021, ' DNA methylation differs extensively between strains of the same geographical origin and changes with age in Daphnia magna ', Epigenetics and Chromatin, vol. 14, 4 . https://doi.org/10.1186/s13072-020-00379-z
Background Patterns of methylation influence lifespan, but methylation and lifespan may also depend on diet, or differ between genotypes. Prior to this study, interactions between diet and genotype have not been explored together to determine their i
Autor:
Casas Sanchez, Aitor, Romero Ramirez, Alessandra, Hargreaves, Eleanor, Ellis, Cameron C, Grajeda, Brian I, Estevao, Igor L, Patterson, Ian, Hughes, Grant, Almeida, Igor C, Zech, Tobias, Acosta-Serrano, Alvaro
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively glycosylates its spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies. These glycans are predicted to modulate spike bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::fd0e6abc42ec7067af5e6e38ae4a8a33
https://archive.lstmed.ac.uk/20026/1/mbio.13_1_03718-21.pdf
https://archive.lstmed.ac.uk/20026/1/mbio.13_1_03718-21.pdf
Autor:
Pleass, Richard
Pathogens frequently use multivalent binding to sialic acid to infect cells or to modulate immunity through interactions with human sialic acid-binding immunoglobulin-type lectins (Siglecs). Molecules that interfere with these interactions could be o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::42d70f2f32aa08015b7e8dc0f39a2091
Publikováno v:
Mobile DNA, Vol 10, Iss 1, Pp 1-6 (2019)
Mobile DNA
Mobile DNA
Transposable elements in prokaryotes are found in many forms and therefore a robust nomenclature system is needed in order to allow researchers to describe and search for them in publications and databases. Here we provide an update on The Transposon
Autor:
Tony Nolan, Samantha M. O’Loughlin, Austin Burt, Andrea Crisanti, Silke Fuchs, Annie J Forster, Tania Dottorini
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
DNA sequences that are exactly conserved over long evolutionary time scales have been observed in a variety of taxa. Such sequences are likely under strong functional constraint and they have been useful in the field of comparative genomics for ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4677e85b4f80fa6d07cdbc21f912dd
https://archive.lstmed.ac.uk/17749/1/TN_oup.pdf
https://archive.lstmed.ac.uk/17749/1/TN_oup.pdf
Autor:
Andrea Crisanti, Ioanna Morianou, Tony Nolan, Nace Kranjc, Andrew Hammond, Kyros Kyrou, Matthew Gribble, Roberto Galizi, Andrea Beaghton, Xenia Karlsson, Austin Burt
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 1, p e1009321 (2021)
PLoS Genetics, Vol 17, Iss 1, p e1009321 (2021)
Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives can be designed to spread and deliberately suppress populations of malaria mosquitoes by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ae0c80541b973c1a7ea2dc87d85310
https://eprints.keele.ac.uk/9143/1/journal.pgen.1009321.pdf
https://eprints.keele.ac.uk/9143/1/journal.pgen.1009321.pdf
Autor:
Natalia Garcia Escude, Hanafy M. Ismail, Mark I. Paine, Mariana Silva dos Santos, Vincent O. Adung'a, Raquel J. Vionette-Amaral, Shannon Quek, James I. MacRae, Clair Rose, Simon C. Wagstaff, Lee R. Haines, Daniel K. Masiga, Aitor Casas-Sanchez, Laith Yakob, Pedro L. Oliveira, Seth M. Barribeau, Alvaro Acosta-Serrano, Marcos Sterkel
Publikováno v:
PLoS Biology
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
PLOS BIOLOGY
PLoS Biology, Vol 19, Iss 1, p e3000796 (2021)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
PLOS BIOLOGY
PLoS Biology, Vol 19, Iss 1, p e3000796 (2021)
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides
Autor:
Riyaz Maderbocus, Vassiliy N. Bavro, Gabriela Boelter, Ian R. Henderson, Douglas G. Ward, Manuel Banzhaf, Timothy J. Knowles, Eva Heinz, Mark Jeeves, Alvin C. K. Teo, Amanda E. Rossiter, David I. Roper, Timothy J. Wells, Adam Colyer, Dema Alodaini, Peter J. Wotherspoon, Yanina R. Sevastsyanovich, Adam F. Cunningham, Faye C. Morris, Shu-Sin Chng, Jack A. Bryant, Douglas F. Browning, Michael Overduin, Pooja Sridhar, Kara A. Staunton, Christopher Icke, Trevor Lithgow, Emily C. A. Goodall, Zhi-Soon Chong
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The Gram-negative outer-membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents, and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane, including DolP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73781758231d185cf3af7872510f68f
http://wrap.warwick.ac.uk/147267/1/WRAP-structure-dual-BON-domain-protein-DolP-identifies-phospholipid-binding-new-mechanism-protein-localisation-Roper-2020.pdf
http://wrap.warwick.ac.uk/147267/1/WRAP-structure-dual-BON-domain-protein-DolP-identifies-phospholipid-binding-new-mechanism-protein-localisation-Roper-2020.pdf
Autor:
Radoslaw P. Kozak, Katherine Wongtrakul-Kish, Iain B. H. Wilson, Katharina Paschinger, Alvaro Acosta-Serrano, Karina Mondragon-Shem, Shi Yan, Daniel Spencer, Matthew E. Rogers
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
During Leishmania transmission sand flies inoculate parasites and saliva into the skin of vertebrates. Saliva has anti-haemostatic and anti-inflammatory activities that evolved to facilitate bloodfeeding, but also modulate the host’s immune respons