Zobrazeno 1 - 10
of 94
pro vyhledávání: '"qiulun lu"'
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Sepsis-induced cardiomyopathy (SICM) is a common and life-threatening complication of sepsis, significantly contributing to elevated mortality. This study aimed to identify crucial indicators for the prompt and early assessment of
Externí odkaz:
https://doaj.org/article/80b473ab80434e03bd007245c12717eb
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116994- (2024)
Background: Myocardial infarction (MI) has emerged as the primary cause of global mortality. Managing blood sugar levels could play a vital role in the treatment of MI. Dapagliflozin (DPG), a commonly used hypoglycemic drug, has demonstrated efficacy
Externí odkaz:
https://doaj.org/article/fad72f7f8aae41b4a3d3e6185290d6b8
Autor:
Xinuo Li, Yuan Sun, Zheng Zhou, Jinran Li, Sai Liu, Long Chen, Yiting Shi, Min Wang, Zheying Zhu, Guangji Wang, Qiulun Lu
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Alzheimer's disease (AD) is a pressing concern in neurodegenerative research. To address the challenges in AD drug development, especially those targeting Aβ, this study uses deep learning and a pharmacological approach to elucidate the pot
Externí odkaz:
https://doaj.org/article/8933bc364c06427d88ab817316ecdf50
Autor:
Han Jiao, Yongjin Wang, Kang Fu, Xiaoao Xiao, Mo-Qiu Jia, Jia Sun, Jingxiao Wang, Guoqing Zhu, Daying Lyu, Qiulun Lu, Yu Peng, Juan Lv, Li Su, Yuanqing Gao
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109067- (2024)
Summary: Orexin is a neuropeptide released from hypothalamus regulating feeding, sleeping, arousal, and cardiovascular activity. Past research has demonstrated that orexin receptor 2 (OX2R) agonist infusion in the brain results in sympathoexcitatory
Externí odkaz:
https://doaj.org/article/3845ac9b38c44a26b9b0353562564f66
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3724 (2024)
Oxidative stress and inflammation play pivotal roles in the progression of deep vein thrombosis (DVT). Fisetin has demonstrated promising pharmacological features; however, its underlying mechanisms in DVT remain elusive. In our study, we investigate
Externí odkaz:
https://doaj.org/article/33b0be91454d405c8b0ec4064e6c0deb
Autor:
Xinuo Li, Dehong Shen, Zheying Zhu, Dayin Lyu, Chang He, Yuan Sun, Jinran Li, Qiulun Lu, Guangji Wang
Publikováno v:
Redox Biology, Vol 64, Iss , Pp 102785- (2023)
There are no effective therapeutic targets or strategies that simultaneously inhibit tumour growth and promote cardiac function recovery. Here, we analyzed targets for cancer treatments and cardiac repair, with demethylation emerging as a common fact
Externí odkaz:
https://doaj.org/article/c0173821e7fd4037a4e4f4f1bf3a7135
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/4d7744c4085044bfa0bb475fc3c4ae24
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/235ea22dc8424ff4b69842fc2638aa3f
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113291- (2022)
Hydroxyurea (HU), a small molecule with various biological properties, was used in myeloproliferative, tumorous, and non-hematological diseases. However, whether HU plays a role in diabetic cardiomyopathy (DCM) remains unclear. Our study aimed to inv
Externí odkaz:
https://doaj.org/article/b2beaa2eacb14f64b10e884383738e3d
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
A 36-year-old male with congenital equinovarus deformity was admitted to the hospital due to worsen deformity. He was known to have ear perforation in childhood. After hospitalization, he received equinovarus correction surgery, fourth toe osteotomy,
Externí odkaz:
https://doaj.org/article/edaf7b0edcec45bea71ff62a41cf90e4