Zobrazeno 1 - 10
of 31
pro vyhledávání: '"qPCR, quantitative (real time) polymerase chain reaction"'
Autor:
Samuel Long
Publikováno v:
Methods (San Diego, Calif.)
Sensitive PCR detection of viral nucleic acids plays a critical role in infectious disease research, diagnosis and monitoring. In the context of SARS-CoV-2 detection, recent reports indicate that digital PCR-based tests are significantly more sensiti
Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut–Brain Axis
Autor:
Noah F. Shroyer, Amy C. Engevik, Sridevi Devaraj, Bradley T. Endres, Berkley Luck, James Versalovic, Heather A. Danhof, Faith D. Ihekweazu, Anne Hall, Zhongcheng Shi, Chonnikant Visuthranukul, Kevin W. Garey, Anthony M. Haag, Robert A. Britton, Sigmund J. Haidacher, Melinda A. Engevik, Alexandra Chang-Graham, Joseph M. Hyser, Thomas D. Horvath
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 221-248 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood. Methods Adult
Autor:
Mark McHugh, Richard J. Martin, Alan P. Robertson, Jo Anne Powell-Coffman, Saurabh Verma, Paul D E Williams
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss, Pp 38-50 (2020)
International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss, Pp 38-50 (2020)
Cholinergic agonists, like levamisole, are a major class of anthelmintic drugs that are known to act selectively on nicotinic acetylcholine receptors (nAChRs) on the somatic muscle and nerves of nematode parasites to produce their contraction and spa
Autor:
Simone Lipinski, Jacqueline Moltzau Anderson, Konrad Aden, Felix Sommer, John F. Baines, Wei-Hung Pan, Olivier Boulard, Robert Häsler, Sven Künzel, Philip Rosenstiel, Stephanie T. Stengel, Richa Bharti, Maren Falk-Paulsen, Ateequr Rehman, Mathias Chamaillard
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 365-389 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Loss-of-function variants in nucleotide-binding oligomerization domain-containing protein 2 (NOD2) impair the recognition of the bacterial cell wall component muramyl-dipeptide and are associated with an increased risk for developin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 391-418 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The miR-34a gene is a direct target of p53 and is commonly silenced in colorectal cancer (CRC). Here we identified the receptor tyrosine kinase CSF1R as a direct miR-34a target and characterized CSF1R as an effector of p53/miR-34a-m
Autor:
Preetha Shridas, Anna-Mart Engelbrecht, Frederick C. de Beer, Willem J.S. de Villiers, Daleen Conradie, Tanja Davis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1329-1341 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1329-1341 (2021)
Background & Aims Identifying new approaches to lessen inflammation, as well as the associated malignant consequences, remains crucial to improving the lives and prognosis of patients diagnosed with inflammatory bowel diseases. Although it previously
Publikováno v:
The Journal of Biological Chemistry
Growing numbers of studies have shown that circular RNAs (circRNAs) can function as regulatory factors to regulate the innate immune response, cell proliferation, cell migration, and other important processes in mammals. However, the function and reg
Autor:
Chise Tateno, Naoki Yamamoto, Chihiro Yamasaki, Takahiro Ochiya, Yuichi Hirata, Michinori Kohara, Yutaka Naito, Yoshiaki Kikkawa, Yuji Ishida, Takahiro Sanada
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 2, Pp 272-283 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: An extracellular vesicle (EV) is a nanovesicle that shuttles proteins, nucleic acids, and lipids, thereby influencing cell behavior. A recent crop of reports have shown that EVs are involved in infectious biology, influencing host
Autor:
Jing Li, Jing Cheng, Jianbo Zhan, Wenjing Zou, Zhaohui Yang, Faxian Zhan, Bing Hu, Ruangang Pan, Deyin Guo
Publikováno v:
Virus Research
Highlights • The research of this paper showed that some suspected SFTS cases are confused with HV infection due to similar symptoms. • No case of simultaneous infection with two or more pathogens was found. • The distribution of SFTSV has a ma
Autor:
Bram Verstockt, Kaline Arnauts, Severine Vermeire, Gert De Hertogh, Sare Verstockt, Marc Ferrante, Gert Van Assche, Marisol Veny, Azucena Salas, Jonas Dehairs
Publikováno v:
Clinical Gastroenterology and Hepatology
BACKGROUND & AIMS: We aimed to identify biomarkers that might be used to predict responses of patients with inflammatory bowel diseases (IBD) to vedolizumab therapy. METHODS: We obtained biopsies from inflamed colon of patients with IBD who began tre