Zobrazeno 1 - 10
of 9 348
pro vyhledávání: '"q-bio.GN"'
Autor:
Liu, Jie, Wu, Xiaotian, Zhang, Kai, Liu, Bing, Bao, Renyi, Chen, Xiao, Cai, Yiran, Shen, Yiming, He, Xinjun, Yan, Jun, Ji, Weixing
With the booming of next generation sequencing technology and its implementation in clinical practice and life science research, the need for faster and more efficient data analysis methods becomes pressing in the field of sequencing. Here we report
Externí odkaz:
http://arxiv.org/abs/2004.00991
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Publikováno v:
Journal of Computational Biology. 30:469-491
The massive amount of genomic data appearing for SARS-CoV-2 since the beginning of the COVID-19 pandemic has challenged traditional methods for studying its dynamics. As a result, new methods such as Pangolin, which can scale to the millions of sampl
Autor:
M. Águila Ruiz-Sola, Serena Flori, Yizhong Yuan, Gaelle Villain, Emanuel Sanz-Luque, Petra Redekop, Ryutaro Tokutsu, Anika Küken, Angeliki Tsichla, Georgios Kepesidis, Guillaume Allorent, Marius Arend, Fabrizio Iacono, Giovanni Finazzi, Michael Hippler, Zoran Nikoloski, Jun Minagawa, Arthur R. Grossman, Dimitris Petroutsos
Publikováno v:
Nature Communications
Nature Communications, 2023, 14 (1), pp.1977. ⟨10.1038/s41467-023-37800-6⟩
Nature Communications, 2023, 14 (1), pp.1977. ⟨10.1038/s41467-023-37800-6⟩
Photosynthetic algae have evolved mechanisms to cope with suboptimal light and CO2 conditions. When light energy exceeds CO2 fixation capacity, Chlamydomonas reinhardtii activates photoprotection, mediated by LHCSR1/3 and PSBS, and the CO2 Concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5426556655b5534f1b62ec1adde5412b
https://hal.science/hal-04075888/document
https://hal.science/hal-04075888/document
Multi-Knock—a multi-targeted genome-scale CRISPR toolbox to overcome functional redundancy in plants
Autor:
Yangjie Hu, Priyanka Patra, Odelia Pisanty, Anat Shafir, Zeinu Mussa Belew, Jenia Binenbaum, Shir Ben Yaakov, Bihai Shi, Laurence Charrier, Gal Hyams, Yuqin Zhang, Maor Trabulsky, Omer Caldararu, Daniela Weiss, Christoph Crocoll, Adi Avni, Teva Vernoux, Markus Geisler, Hussam Hassan Nour-Eldin, Itay Mayrose, Eilon Shani
Publikováno v:
Nature Plants
Nature Plants, In press, ⟨10.1038/s41477-023-01374-4⟩
Nature Plants, In press, ⟨10.1038/s41477-023-01374-4⟩
International audience; Plant genomes are characterized by large and complex gene families that often result in similar and partially overlapping functions 1. This genetic redundancy severely hampers current efforts to uncover novel phenotypes, delay
Publikováno v:
Heredity. 130:320-328
Genomic selection has increased genetic gain in several livestock species, but due to the complicated genetics and reproduction biology not yet in honey bees. Recently, 2 970 queens were genotyped to gather a reference population. For the application
Autor:
Lily Chen, Andrea Hill, Jean-Louis Petit, Aline Mariage, Véronique de Berardinis, Salwa Karboune
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, 2023, 18 (3), pp.465-475. ⟨10.1021/acschembio.2c00728⟩
ACS Chemical Biology, 2023, 18 (3), pp.465-475. ⟨10.1021/acschembio.2c00728⟩
International audience
Autor:
Isabelle Testard, Elizabeth Garcia-Chartier, Amani Issa, Véronique Collin-Faure, Catherine Aude-Garcia, Serge M Candéias
Publikováno v:
Journal of Radiation Research
Journal of Radiation Research, In press, ⟨10.1093/jrr/rrac094⟩
Journal of Radiation Research, In press, ⟨10.1093/jrr/rrac094⟩
Irradiated cells can propagate signals to neighboring cells. Manifestations of these so-called bystander effects (BEs) are thought to be relatively more important after exposure to low- vs high-dose radiation and can be mediated via the release of se
Development of versatile allele-specific siRNAs able to silence all the dominant dynamin 2 mutations
Autor:
Swati Dudhal, Lylia Mekzine, Bernard Prudhon, Karishma Soocheta, Bruno Cadot, Kamel Mamchaoui, Delphine Trochet, Marc Bitoun
Publikováno v:
Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, 2022, 29, pp.733-748. ⟨10.1016/j.omtn.2022.08.016⟩
Molecular Therapy-Nucleic Acids, 2022, 29, pp.733-748. ⟨10.1016/j.omtn.2022.08.016⟩
International audience; Dominant centronuclear myopathy (CNM) is a rare form of congenital myopathy associated with a wide clinical spectrum, from severe neonatal to milder adult forms. There is no available treatment for this disease due to heterozy
Autor:
Ihtiyar, Musa Nuri, Ozgur, Arzucan
Language models, primarily transformer-based ones, obtained colossal success in NLP. To be more precise, studies like BERT in NLU and works such as GPT-3 for NLG are very crucial. DNA sequences are very close to natural language in terms of structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83174e6b660e6bb43900e4c27ac59e0
http://arxiv.org/abs/2307.10634
http://arxiv.org/abs/2307.10634