Zobrazeno 1 - 10
of 51
pro vyhledávání: '"pyruvate dehydrogenase kinase (PDK)"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pulmonary arterial hypertension (PAH) is an orphan disease of the cardiopulmonary unit that reflects an obstructive pulmonary vasculopathy and presents with hypertrophy, inflammation, fibrosis, and ultimately failure of the right ventricle (RVF). Des
Externí odkaz:
https://doaj.org/article/64554359d0784373a842712ef55189d2
Autor:
Caroline E. Nunes-Xavier, Janire Mingo, Maite Emaldi, Karine Flem-Karlsen, Gunhild M. Mælandsmo, Øystein Fodstad, Roberto Llarena, José I. López, Rafael Pulido
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by pyruvate decarboxylation, which drives energy metabolism during cell growth, including prostate cancer (PCa) cell growth. The major catalytic subunit of PDH, PDHA1, i
Externí odkaz:
https://doaj.org/article/060cb01a32194d9ab44dea2f0e95b000
Publikováno v:
Heliyon, Vol 8, Iss 2, Pp e08889- (2022)
Aims: Pyruvate dehydrogenase (PDH) catalyzes the decarboxylation of pyruvate to acetyl-CoA, which plays a key role in linking cytosolic glycolysis to mitochondria metabolism. PDH is physiologically inactivated by pyruvate dehydrogenase kinases (PDKs)
Externí odkaz:
https://doaj.org/article/42a7338c8fe24cb38aa8a54d8c4c0604
Autor:
Cassandra L. R. van Doorn, Gina K. Schouten, Suzanne van Veen, Kimberley V. Walburg, Jeroen J. Esselink, Matthias T. Heemskerk, Frank Vrieling, Tom H. M. Ottenhoff
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Global increases in the prevalence of antimicrobial resistance highlight the urgent need for novel strategies to combat infectious diseases. Recent studies suggest that host metabolic pathways play a key role in host control of intracellular bacteria
Externí odkaz:
https://doaj.org/article/01155c0bee704eccac2e991f18f0b985
Autor:
Yongxian Zhuang, Reynold C. Ly, Carleigh V. Frazier, Jia Yu, Sisi Qin, Xiao-Yang Fan, Matthew P. Goetz, Judy C. Boughey, Richard Weinshilboum, Liewei Wang
Publikováno v:
Cancer & Metabolism, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background The role of tumor protein D54 in breast cancer has not been studied and its function in breast cancer remains unclear. In our previous pharmacogenomic studies using lymphoblastoid cell line (LCL), this protein has been identified
Externí odkaz:
https://doaj.org/article/f44d3e367d16440cb592aa58f59dbd89
Publikováno v:
European Medical Journal, Vol 3, Iss 2, Pp 42-49 (2018)
Gastric cancer is the second most common cause of cancer-related deaths worldwide, and the 5-year overall survival rate for advanced gastric cancer is ≤25%. Metabolism is a critical process for maintaining growth and other functions in cancer cells
Externí odkaz:
https://doaj.org/article/df199b1630be49e6b448127e2aaed709
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Song Hee Lee, Bo Young Choi, A Ra Kho, Dae Ki Hong, Beom Seok Kang, Min Kyu Park, Si Hyun Lee, Hui Chul Choi, Hong Ki Song, Sang Won Suh
Publikováno v:
Nutrients; Volume 14; Issue 22; Pages: 4804
During seizure activity, glucose and Adenosine triphosphate (ATP) levels are significantly decreased in the brain, which is a contributing factor to seizure-induced neuronal death. Dichloroacetic acid (DCA) has been shown to prevent cell death. DCA i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2669299a0b3ca4708175f49a7e70c6ec
https://doi.org/10.3390/nu14224804
https://doi.org/10.3390/nu14224804
Autor:
Matthias T. Heemskerk, Jeroen J. Esselink, Kimberley V. Walburg, Tom H. M. Ottenhoff, Frank Vrieling, Gina K. Schouten, Cassandra L. R. van Doorn, Suzanne C. van Veen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 12. FRONTIERS MEDIA SA
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 12. FRONTIERS MEDIA SA
Frontiers in Immunology, Vol 12 (2021)
Global increases in the prevalence of antimicrobial resistance highlight the urgent need for novel strategies to combat infectious diseases. Recent studies suggest that host metabolic pathways play a key role in host control of intracellular bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfbe53b44c9bd9bdc80e869fe713b15
https://pubmed.ncbi.nlm.nih.gov/34552598
https://pubmed.ncbi.nlm.nih.gov/34552598
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.