Zobrazeno 1 - 10
of 1 600
pro vyhledávání: '"pyrimidine salvage pathway"'
Autor:
Fatima Zohra Delma, Dong-Hoon Yang, Alfredo Cabrera-Orefice, Jordy Coolen, Abdullah M. S. Al-Hatmi, Sarah A. Ahmed, Willem J. G. Melchers, Yun C. Chang, Kyung J. Kwon-Chung, Sybren de Hoog, Paul E. Verweij, Jochem B. Buil
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract Cryptococcal meningitis is a high-mortality infection. Adding 5-fluorocytosine (5-FC) to its treatment improves outcomes, but resistance to 5-FC presents a significant challenge. We conducted whole-genome sequencing on seven C. neoformans is
Externí odkaz:
https://doaj.org/article/a90c5da1a1884c8d96a3de3bdc41a70b
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 101-119 (2024)
Yin Li,1,* Manling Jiang,2,3,* Yongqi Wei,1,* Xiang He,2 Guoping Li,2,* Chunlai Lu,1 Di Ge1 1Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Laboratory of Allergy and Prec
Externí odkaz:
https://doaj.org/article/9d02c09f071a454ca5531fc076fd77e5
Publikováno v:
The Plant Cell, 2005 Jul 01. 17(7), 2077-2088.
Externí odkaz:
https://www.jstor.org/stable/4130919
Autor:
Lukas Birštonas, Alex Dallemulle, Manuel S. López-Berges, Ilse D. Jacobsen, Martin Offterdinger, Beate Abt, Maria Straßburger, Ingo Bauer, Oliver Schmidt, Bettina Sarg, Herbert Lindner, Hubertus Haas, Fabio Gsaller
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Selectable markers are indispensable for genetic engineering, yet their number and variety are limited. Most selection procedures for prototrophic cells rely on the introduction of antibiotic resistance genes. New minimally invasive tools ar
Externí odkaz:
https://doaj.org/article/1b785454018f47a2a970ea48abd09134
Akademický článek
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Autor:
Del Arco, Jon1, Fernández-Lucas, Jesús1,2 jesus.fernandez2@universidadeuropea.es
Publikováno v:
Applied Microbiology & Biotechnology. Sep2018, Vol. 102 Issue 18, p7805-7820. 16p.
Publikováno v:
Genomics & Genetics Weekly; 10/4/2024, p734-734, 1p
Akademický článek
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Autor:
Maria Straßburger, Herbert Lindner, Alex Dallemulle, Oliver Schmidt, Lukas Birstonas, Fabio Gsaller, Manuel Sánchez López-Berges, Beate Abt, Ingo Bauer, Ilse D. Jacobsen, Bettina Sarg, Hubertus Haas, Martin Offterdinger
Publikováno v:
mBio
mBio, Vol 11, Iss 2 (2020)
mBio, Vol 11, Iss 2, p e00230-20 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio, Vol 11, Iss 2, p e00230-20 (2020)
This work reports the discovery of a novel genetic toolbox comprising multiple, endogenous selectable markers for targeted genomic insertions of DNAs of interest (DOIs). Marker genes encode proteins involved in 5-fluorocytosine uptake and pyrimidine
Autor:
Paulina Aguilera-Alvarado, Christelle Mazubert, Sobeida Sánchez-Nieto, José Antonio Pedroza-Garcia, Manuela Nájera-Martínez, Jeannine Drouin-Wahbi, Javier Plasencia, José M. Gualberto, Cécile Raynaud
Publikováno v:
Plant Journal
Plant Journal, 2018, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
Plant Journal, Wiley, 2018, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
Plant Journal, Wiley, 2019, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
Plant Journal, 2018, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
Plant Journal, Wiley, 2018, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
Plant Journal, Wiley, 2019, 97 (3), pp.430-446. ⟨10.1111/tpj.14128⟩
International audience; Nucleotide biosynthesis proceeds through a de novo pathway and a salvage route. In the salvage route, free bases and/or nucleosides are recycled to generate the corresponding nucleotides. Thymidine kinase (TK) is the first enz