Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Autor: Tanos C. C. França, Angelo A.T. da Silva, Leandro B. Bernardo, Eugenie Nepovimova, Vinicius C V da Rocha, Taynara Carvalho-Silva, Thiago H. Silva, Cintia N. Ferreira, Joyce S. F. D. de Almeida, Wellington V Dos Santos, Rafael B. Rodrigues, Samir F. de A. Cavalcante, Kamil Kuca, Daniel A. S. Kitagawa, Alessandro B. C. Simas

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1369-1376 (2021)

Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a bro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50d48cd3065be20ef284226717b5ba8
https://doi.org/10.1080/14756366.2021.1916009

FINE-TUNING THE SUPRAMOLECULAR SYNTHETIC CONDITIONS OF ACAC-BASED CU(II) COMPLEXES WITH A SERIES OF PYRIDILOXIMES

Autor: Šmital, Luka, Borovina, Mladen, Đaković, Marijana

The main focus of supramolecular chemistry has for a long been put on studying the noncovalent interactions that are responsible for spatial organization of molecules in a system. It has been known that by modifying certain features, such as electron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::bcfc0dd74849d3e5c96341ce5f268111
https://www.bib.irb.hr/910870

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