Zobrazeno 1 - 10
of 4 603
pro vyhledávání: '"pyrazoline"'
Autor:
Monika Sihag, Anju Manuja, Swati Rani, Rinku Soni, Neha Rani, Sandeep Malik, Kirti Bhardwaj, Balvinder Kumar, Mayank Kinger, Monika Miglani, Deepak Kumar Aneja
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100204- (2024)
In the present paper, pyrazole and pyrazoline derivatives of β-ionone were synthesized. The protocol involved intramolecular oxidative C–H amination of hydrazone to yield corresponding pyrazole in moderate to good yields. Another methodology compr
Externí odkaz:
https://doaj.org/article/16c543f4d7d64967a3efa4c467eb7e0e
Autor:
Serghei Pogrebnoi
Publikováno v:
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, Vol 19, Iss 1, Pp 9-28 (2024)
This review will primarily focus on recent methods employed for the synthesis of a diverse array of chalcones with broad-ranging biological activities, with a particular emphasis on the past five years. The utilization of aromatic methyl ketones and
Externí odkaz:
https://doaj.org/article/ee1b7765504046e6880bc771174c23cf
Autor:
Pamungkas Bagus Satriyo, Mustofa Mustofa, Tutik Dwi Wahyuningsih, Ema Damayanti, Hesti Lina Wiraswati, Denny Satria, M. Hasan Bashari, Eti Nurwening Sholikhah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Protein kinase dysregulation induces cancer cell aggressiveness leading to rapid tumor progression and poor prognosis in TNBC patients. Many small-molecule kinase inhibitors have been tested in clinical trials to treat TNBC patients. In the
Externí odkaz:
https://doaj.org/article/30cef5ff156345929d8e0016053292e9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Two new series of oxadiazole and pyrazoline derivatives were designed and synthesized as promising EGFR-TK inhibitors. The in vitro antiproliferative activity was studied against three human cancer cell lines; HCT116, HepG-2 and MCF7 using M
Externí odkaz:
https://doaj.org/article/6284f0a0aa3541e7984ea263ae2507cf
Autor:
Wiraswati HL, Bashari MH, Alfarafisa NM, Ma'ruf IF, Sholikhah EN, Wahyuningsih TD, Satriyo PB, Mustofa M, Satria D, Damayanti E
Publikováno v:
Advances and Applications in Bioinformatics and Chemistry, Vol Volume 17, Pp 33-46 (2024)
Hesti Lina Wiraswati,1,2 Muhammad Hasan Bashari,1,2 Nayla Majeda Alfarafisa,1,2 Ilma Fauziah Ma’ruf,3 Eti Nurwening Sholikhah,4 Tutik Dwi Wahyuningsih,5 Pamungkas Bagus Satriyo,4 Mustofa Mustofa,4 Denny Satria,6 Ema Damayanti7 1Department of Biomed
Externí odkaz:
https://doaj.org/article/676e0862bab342fc8a6442c469b784f5
Publikováno v:
Results in Chemistry, Vol 8, Iss , Pp 101570- (2024)
In present study, two pyrazoline derivatives were synthesized and characterized. The synthesized pyrazoline derivatives 6 and 9 were screened for their antibacterial activity against two Gram-negative bacteria (E. coli and P. aeruginosa) and two Gram
Externí odkaz:
https://doaj.org/article/ca7aedddb2664a729178d267c2af4b11
Publikováno v:
Journal of Tropical Pharmacy and Chemistry, Vol 8, Iss 1 (2024)
Pyrazoline is an alkaloid compound which has various biological activities such as antibacterial, antifungal, antitumor and anticancer. The compound N-carbotioamide-3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)pyrazoline was successfully synth
Externí odkaz:
https://doaj.org/article/c88862882e6442eb85de5ccf0d382336
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 1 (2024)
Abstract Compounds with a pyrazoline scaffold are useful as sensors for fluorescence detection of different types of analytes. Recovery of a pyrazoline-based sensor with a view to use it recurrently would be more facile when the sensing molecule is a
Externí odkaz:
https://doaj.org/article/046abc2e89104a3a83cfea366f2efa76
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1757 (2024)
The reaction of 4-(4-bromophenyl)-2,4-dioxobutanoic acid with thiosemicarbazide, in a ratio of 1:2, when boiled in ethanol gives 3-(4-bromophenyl)-1-carbamothioyl-5-(2-carbamothioylhydrazinyl)-4,5-dihydro-1H-pyrazole-5-carboxylic acid with a good yie
Externí odkaz:
https://doaj.org/article/76085b606ab7457bbd9dd520daacd44e
Autor:
Chandra Shekhar Yadav, Iqbal Azad, Abdul Rahman Khan, Malik Nasibullah, Naseem Ahmad, Dhananjoy Hansda, Saud Nusrat Ali, Kajal Shrivastav, Mohd Akil, Minaxi B. Lohani
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101326- (2024)
The pyrazoline scaffold plays a vital role in heterocyclic chemistry as a fundamental building block in both organic and medicinal chemistry. A pyrazoline scaffold is composed of an endocyclic double bond, two nitrogen atoms, and five different types
Externí odkaz:
https://doaj.org/article/e2deaec543974e129d2faf299d351de5