Zobrazeno 1 - 10
of 46
pro vyhledávání: '"pulvomycin"'
Akademický článek
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Publikováno v:
Biomedicines, Vol 9, Iss 4, p 436 (2021)
Although docetaxel-based regimens are common and effective for early-stage triple-negative breast cancer (TNBC) treatment, acquired drug resistance frequently occurs. Therefore, a novel therapeutic strategy for docetaxel-resistant TNBC is urgently re
Externí odkaz:
https://doaj.org/article/2b4759c8c35848cb974b49a26e723122
Publikováno v:
Journal of antibiotics. 74:825-829
Menaquinone is an essential cofactor in the electron-transfer pathway for bacteria. Menaquinone is biosynthesized from chorismate using either the well-known canonical pathway established by pioneering studies in model microorganisms or the futalosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc68614b8b9ddcf6430abbf6084a2d5
http://hdl.handle.net/2115/84174
http://hdl.handle.net/2115/84174
Akademický článek
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Autor:
Sunghoon Hwang, Kyuho Moon, Jongheon Shin, Ki-Bong Oh, Eunji Kim, Yeo Joon Yoon, Jeongyoon Sun, Dong-Chan Oh, So Hyun Park, Sangwon Cha, Evan Setiawan Riandi, Jinsheng Cui, Daniel Shin, Jun Young Park, Woong Sub Byun, Youngju Kal, Sang Kook Lee
Publikováno v:
Organic Letters. 22:5358-5362
Pulvomycins B-D (1-3) were discovered from an estuarine Streptomyces strain along with the known pulvomycin (4). The 22-membered macrocyclic lactone structures of 1-3 were determined based on the interpretation of NMR, UV, and MS data, the modified M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::334bb73c0d912c680662b5f66e961247
https://doi.org/10.1021/acs.orglett.0c01249
https://doi.org/10.1021/acs.orglett.0c01249
Publikováno v:
Chemistry – A European Journal. 28
A synthetic route to the pulvomycin class of natural products is presented, which culminated in the first synthesis of a pulvomycin, pulvomycin D. Key elements of the strategy include a pivotal aldol reaction which led to bond formation between the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90263d3271f35b337ffed717bc54ea5a
https://doi.org/10.1002/chem.202104064
https://doi.org/10.1002/chem.202104064
Publikováno v:
Biomedicines, Vol 9, Iss 436, p 436 (2021)
Biomedicines
Volume 9
Issue 4
Biomedicines
Volume 9
Issue 4
Although docetaxel-based regimens are common and effective for early-stage triple-negative breast cancer (TNBC) treatment, acquired drug resistance frequently occurs. Therefore, a novel therapeutic strategy for docetaxel-resistant TNBC is urgently re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4891262960e5cc198522d7e8a3f158
https://www.mdpi.com/2227-9059/9/4/436
https://www.mdpi.com/2227-9059/9/4/436
Publikováno v:
Molecular Microbiology. 106:22-34
Elfamycins are a relatively understudied group of antibiotics that target the essential process of translation through impairment of EF-Tu function. For the most part, the utility of these compounds has been as laboratory tools for the study of EF-Tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b492b3abced1676fa6a71ec82867b8
https://doi.org/10.1111/mmi.13750
https://doi.org/10.1111/mmi.13750
Akademický článek
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Autor:
Sandra Börding, Thorsten Bach
Publikováno v:
Chem. Commun.. 50:4901-4903
The C24–C40 fragment of (−)-pulvomycin was prepared in enantiomerically pure form using a concise synthesis method (15 linear steps from d-fucose, 6.8% overall yield) featuring a diastereoselective addition to an aldehyde, a β-selective glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a805e9a44968ac320040809d47350c
https://doi.org/10.1039/c4cc01338g
https://doi.org/10.1039/c4cc01338g