Výsledky vyhledávání - "proximal tubule dysfunction"

Prevalence of tubulopathy and association with renal function loss in HIV-infected patients

Autor: Emmanuelle Plaisier, Marie-Gisèle Lebrette, Pierre Ronco, Emmanuel Esteve, Jacqueline Capeau, J.-B. Guiard-Schmid, Soraya Fellahi, Anne-Line Eme, Gilles Pialoux, François-Xavier Lescure, Dominique Costagliola, Jean-Philippe Bastard

Publikováno v: Nephrology Dialysis Transplantation
Nephrology Dialysis Transplantation, Oxford University Press (OUP), 2019, ⟨10.1093/ndt/gfz081⟩
Nephrol Dial Transplant

Background The incidence of chronic kidney disease (CKD) is 10 times higher in human immunodeficiency virus (HIV)-infected patients than in the general population. We explored the prevalence and determinants of proximal tubular dysfunction (PTD) in H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b27c3d62e5588b7352328c259c0ce23
https://doi.org/10.1093/ndt/gfz081

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P1005LONG NONCODING RNAS MAY INTERVENE IN PODOCYTE INJURY AND PROXIMAL TUBULE DYSFUNCTION THROUGH MODULATING MIRNAS EXPRESSION IN EARLY DIABETIC KIDNEY DISEASE OF TYPE 2 DIABETES MELLITUS PATIENTS

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims Interactions among multiple molecules and signalling pathways contribute to the pathogenesis and progression of diabetic kidney disease (DKD). Long noncoding RNAs (lncRNAs) play key roles in the pathophysiology of DKD involving ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fa057038ce039f3dd16ba40040be359
https://doi.org/10.1093/ndt/gfaa142.p1005

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Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome

Autor: Julia, Flemming, Maike, Marczenke, Ina-Maria, Rudolph, Rikke, Nielsen, Tina, Storm, Ilsoe Christensen, Erik, Sebastian, Diecke, Francesco, Emma, Thomas E, Willnow

Publikováno v: Flemming, J, Marczenke, M, Rudolph, I M, Nielsen, R, Storm, T, Christensen, E I, Diecke, S, Emma, F & Willnow, T E 2020, ' Induced pluripotent stem cell-based disease modeling identifies ligand-induced decay of megalin as a cause of Donnai-Barrow syndrome ', Kidney International, vol. 98, no. 1, pp. 159-167 . https://doi.org/10.1016/j.kint.2020.02.021
Kidney International

Donnai-Barrow syndrome (DBS) is an autosomal-recessive disorder characterized by multiple pathologies including malformation of forebrain and eyes, as well as resorption defects of the kidney proximal tubule. The underlying cause of DBS are mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d2bf201bb479df0e4ea0ede51d85e907
https://pure.au.dk/ws/files/220252028/1_s2.0_S0085253820302635_main.pdf

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High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy

Autor: Henrik Birn, Jing Xiao, Lu Wen, Zheng Wang, Zhanzheng Zhao, Jon Waarst Gregersen

Publikováno v: Wen, L, Zhao, Z, Wang, Z, Xiao, J, Birn, H & Gregersen, J W 2019, ' High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy ', Nephrology (Carlton, Vic.), vol. 24, no. 7, pp. 703-710 . https://doi.org/10.1111/nep.13477
Wen, L, Zhao, Z, Wang, Z, Xiao, J, Birn, H & Gregersen, J W 2019, ' High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy ', Nephrology, vol. 24, no. 7, pp. 703-710 . https://doi.org/10.1111/nep.13477

Aim Complement activation is involved in the pathogenesis and progression of immunoglobulin A nephropathy (IgAN); however, the clinical implication of abnormal complement protein levels in serum and urine is not clear. To address this we analyzed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3f66b6e70917720db161f1f90b16a5
https://vbn.aau.dk/da/publications/3307c404-a257-4960-aa6c-919f0b9cea71

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