Zobrazeno 1 - 10 of 64 pro vyhledávání: '"proteoglycan (PG"'
1
Akademický článek
Current status of immunological therapies for rheumatoid arthritis with a focus on antigen-specific therapeutic vaccines
Autor: Daniel H. Zimmerman, Zoltan Szekanecz, Adrienn Markovics, Kenneth S. Rosenthal, Roy E. Carambula, Katalin Mikecz
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Rheumatoid arthritis (RA) is recognized as an autoimmune joint disease driven by T cell responses to self (or modified self or microbial mimic) antigens that trigger and aggravate the inflammatory condition. Newer treatments of RA employ monoclonal a
Externí odkaz: https://doaj.org/article/e4aec4b93f5348f99a094ae2c4a12b9e
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2
Akademický článek
Protective Role of Decorin in Primary Hepatocellular Carcinoma
Autor: Andrea Reszegi, Zsolt Horváth, Hajnalka Fehér, Barnabás Wichmann, Péter Tátrai, Ilona Kovalszky, Kornélia Baghy
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Hepatocellular carcinoma (HCC) represents one of the most frequent type of primary liver cancers. Decorin, a small leucine-rich proteoglycan of the extracellular matrix, represents a powerful tumor cell growth and migration inhibitor by hindering rec
Externí odkaz: https://doaj.org/article/4efffd2db2264e2ebeb81fc4b147a128
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3
Akademický článek
Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis
Autor: Daniel H. Zimmerman, Katalin Mikecz, Adrienn Markovics, Roy E. Carambula, Jason C. Ciemielewski, Daniel M. Toth, Tibor T. Glant, Ken S. Rosenthal
Publikováno v: Vaccines, Vol 9, Iss 5, p 448 (2021)
Rheumatoid arthritis (RA) can be initiated and driven by immune responses to multiple antigenic epitopes including those in cartilage proteoglycan (PG, aggrecan) and type II collagen. RA is driven by T helper 1 (Th1) or Th17 pro-inflammatory T cell r
Externí odkaz: https://doaj.org/article/917db455b8474722af7ecbb433438e1f
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4
Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles
Autor: Morihisa Fujita, Shuji Mizumoto, Yi-Fan Huang
Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans. More than 50 gene pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca720612dae5d79a1c55c0d368995a06
http://europepmc.org/articles/PMC8450405
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5
Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis
Autor: Roy E. Carambula, Daniel H. Zimmerman, Tibor T. Glant, Ken S. Rosenthal, Daniel M. Toth, Adrienn Markovics, Katalin Mikecz, Jason C. Ciemielewski
Publikováno v: Vaccines
Volume 9
Issue 5
Vaccines, Vol 9, Iss 448, p 448 (2021)
Rheumatoid arthritis (RA) can be initiated and driven by immune responses to multiple antigenic epitopes including those in cartilage proteoglycan (PG, aggrecan) and type II collagen. RA is driven by T helper 1 (Th1) or Th17 pro-inflammatory T cell r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46136d08d3eeb8dbc3272a4ade366fd
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6
Akademický článek
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7
IGF-1 Upregulates Biglycan and Decorin by Increasing Translation and Reducing ADAMTS5 Expression
Autor: Hanon Lee, Jang Hee Oh, Soyun Cho, Jiyeong Lim, Jin Ho Chung
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1403, p 1403 (2021)
Proteoglycan (PG) is a glycosaminoglycan (GAG)-conjugated protein essential for maintaining tissue strength and elasticity. The most abundant skin PGs, biglycan and decorin, have been reported to decrease as skin ages. Insulin-like growth factor-1 (I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8edfd615b70e0465ac9201248797e91
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8
Protective Role of Decorin in Primary Hepatocellular Carcinoma
Autor: Zsolt Horváth, Andrea Reszegi, Kornélia Baghy, Péter Tátrai, Ilona Kovalszky, Barnabás Wichmann, Hajnalka Fehér
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Hepatocellular carcinoma (HCC) represents one of the most frequent type of primary liver cancers. Decorin, a small leucine-rich proteoglycan of the extracellular matrix, represents a powerful tumor cell growth and migration inhibitor by hindering rec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9b6a6a94d7f116739bdd7fd146ca2a
https://www.frontiersin.org/article/10.3389/fonc.2020.00645/full
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9
Akademický článek
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10
Akademický článek
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