Zobrazeno 1 - 10 of 54 pro vyhledávání: '"proteins drug target"'
1
Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads
Autor: Irene Kouskoumvekaki, Damian R. Plichta, Kasper P. Jensen, Gianni Panagiotou
Publikováno v: Jensen, K, Plichta, D R, Panagiotou, G & Kouskoumvekaki, I 2012, ' Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads ', Molecular BioSystems, vol. 8, no. 6, pp. 1678-1685 . https://doi.org/10.1039/c2mb00008c
The parasite Plasmodium falciparum is the main agent responsible for malaria. In this study, we exploited a recently published chemical library from GlaxoSmithKline (GSK) that had previously been confirmed to inhibit parasite growth of the wild type
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088fd7084a6d223f48e061f5ef5f313b
https://pubmed.ncbi.nlm.nih.gov/22446744
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2
Akademický článek
ncRNAs associated with drug resistance and the therapy of digestive system neoplasms.
Autor: Feng, Wei, Su, Zhangyao, Yin, Qingqing, Zong, Wei, Shen, Xianjuan, Ju, Shaoqing
Publikováno v: Journal of Cellular Physiology; Nov2019, Vol. 234 Issue 11, p19143-19157, 15p
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3
Akademický článek
Systematic comparison of differential expression networks in MTB mono-, HIV mono- and MTB/HIV co-infections for drug repurposing.
Autor: Jiang, Yao1 (AUTHOR), Zhang, Jia-Xuan1 (AUTHOR), Liu, Rong1 (AUTHOR) liurong116@mail.hzau.edu.cn
Publikováno v: PLoS Computational Biology. 12/19/2022, Vol. 18 Issue 12, p1-32. 32p. 5 Diagrams, 6 Graphs.
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4
Akademický článek
review of machine learning approaches for drug synergy prediction in cancer.
Autor: Torkamannia, Anna1 (AUTHOR), Omidi, Yadollah2 (AUTHOR), Ferdousi, Reza1 (AUTHOR) ferdousi.r@gmail.com
Publikováno v: Briefings in Bioinformatics. May2022, Vol. 23 Issue 3, p1-19. 19p.
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5
Akademický článek
Drug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence.
Autor: Hsieh, Kanglin1 (AUTHOR), Wang, Yinyin2 (AUTHOR), Chen, Luyao1 (AUTHOR), Zhao, Zhongming3 (AUTHOR), Savitz, Sean4 (AUTHOR), Jiang, Xiaoqian1 (AUTHOR), Tang, Jing2 (AUTHOR), Kim, Yejin1 (AUTHOR) yejin.kim@uth.tmc.edu
Publikováno v: Scientific Reports. 11/30/2021, Vol. 11 Issue 1, p1-13. 13p.
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6
Akademický článek
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery.
Autor: Liu, Xiaonan1,2 (AUTHOR), Huuskonen, Sini1,2 (AUTHOR), Laitinen, Tuomo3 (AUTHOR), Redchuk, Taras1,2 (AUTHOR), Bogacheva, Mariia2,4,5 (AUTHOR), Salokas, Kari1,2 (AUTHOR), Pöhner, Ina3 (AUTHOR), Öhman, Tiina1,2 (AUTHOR), Tonduru, Arun Kumar3 (AUTHOR), Hassinen, Antti2,4 (AUTHOR), Gawriyski, Lisa1,2 (AUTHOR), Keskitalo, Salla1,2 (AUTHOR), Vartiainen, Maria K1,2 (AUTHOR), Pietiäinen, Vilja2,4 (AUTHOR), Poso, Antti3,6 (AUTHOR), Varjosalo, Markku1,2 (AUTHOR) markku.varjosalo@helsinki.fi
Publikováno v: Molecular Systems Biology. Nov2021, Vol. 17 Issue 11, p1-26. 26p.
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7
Akademický článek
PreDTIs: prediction of drug–target interactions based on multiple feature information using gradient boosting framework with data balancing and feature selection techniques.
Autor: Mahmud, S M Hasan1 (AUTHOR), Chen, Wenyu1 (AUTHOR) m.moni@unsw.edu.au, Liu, Yongsheng1 (AUTHOR), Awal, Md Abdul2 (AUTHOR), Ahmed, Kawsar3 (AUTHOR), Rahman, Md Habibur4 (AUTHOR), Moni, Mohammad Ali5 (AUTHOR) m.moni@unsw.edu.au
Publikováno v: Briefings in Bioinformatics. Sep2021, Vol. 22 Issue 5, p1-20. 20p.
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8
Akademický článek
PATHOPHYSIOLOGY AND PATHOGENIC MECHANISMS OF PULMONARY HYPERTENSION: ROLE OF MEMBRANE RECEPTORS, ION CHANNELS, AND CA2+ SIGNALING.
Autor: Balistrieri, Angela, Makino, Ayako, Yuan, Jason X.-J.
Publikováno v: Physiological Reviews; Jul2023, Vol. 103 Issue 3, p1827-1897, 71p
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10
Akademický článek
QuoteTarget: A sequence‐based transformer protein language model to identify potentially druggable protein targets.
Autor: Chen, Jiaxiao, Gu, Zhonghui, Xu, Youjun, Deng, Minghua, Lai, Luhua, Pei, Jianfeng
Publikováno v: Protein Science: A Publication of the Protein Society; Feb2023, Vol. 32 Issue 2, p1-14, 14p
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