Zobrazeno 1 - 10
of 61
pro vyhledávání: '"proteinase activated receptor 1"'
Publikováno v:
Thrombosis Research
bioRxiv
bioRxiv
COVID-19 has caused over 1 million deaths globally, yet the cellular mechanisms underlying severe disease remain poorly understood. By analyzing several thousand plasma proteins in 306 COVID-19 patients and 78 symptomatic controls over serial timepoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e3ec2a9b16c150f69513abb0ae2dd0
https://doi.org/10.1016/j.thromres.2021.05.016
https://doi.org/10.1016/j.thromres.2021.05.016
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 9:599-606
To study thrombin (TM) damage effect and detailed quantitative relation on cerebral vessels function, and to explore inflammatory mechanism of TM on cerebral vasospasm (CVS) in vivo. Wild type SD rats were randomly assigned into different groups for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44fcf6a24df7d61cabf33b8e83b015d8
https://doi.org/10.1166/jbt.2019.2024
https://doi.org/10.1166/jbt.2019.2024
Publikováno v:
American Journal of Physiology-Cell Physiology. 316:C377-C392
Activated coagulation factor XI (FXIa) is a serine proteinase that plays a key role in the intrinsic coagulation pathway. The analysis of FXI-knockout mice has indicated the contribution of FXI to the pathogenesis of atherosclerosis. However, the und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee71d484c99cb10ce0a4d192f1b98001
https://doi.org/10.1152/ajpcell.00426.2018
https://doi.org/10.1152/ajpcell.00426.2018
Autor:
David A. Goukassian, Lahouaria Hadri, Kenneth Fish, Malik Bisserier, Walid Hamouche, Abrisham Eskandari, Agnieszka Brojakowska
Publikováno v:
Journal of Molecular and Cellular Cardiology
The first confirmed case of novel Coronavirus Disease 2019 (COVID-19) in the United States was reported on January 20, 2020. As of November 24, 2020, close to 12.2 million cases of COVID-19 was confirmed in the US, with over 255,958 deaths. The rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d439cbf7ea2e5b22768fd838287da5
https://pubmed.ncbi.nlm.nih.gov/33373644
https://pubmed.ncbi.nlm.nih.gov/33373644
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 127(6)
In situ thrombus formation is one of the major pathological features of pulmonary hypertension (PH). The mechanism of in situ thrombosis has not been clearly identified. Fibrinogen-like protein 2 (FGL2) prothrombinase is an immune coagulant that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b66abe8bbc78a7afe18b1722341910
https://pubmed.ncbi.nlm.nih.gov/31580221
https://pubmed.ncbi.nlm.nih.gov/31580221
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:2-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fecaa741b9bedfad985b9a04d00a705f
https://doi.org/10.1254/jpssuppl.92.0_2-o-30
https://doi.org/10.1254/jpssuppl.92.0_2-o-30
Autor:
Toby M. Maher
Publikováno v:
Clinics in Chest Medicine. 33:69-83
Idiopathic pulmonary fibrosis (IPF) is a progressive disease of unknown cause that conveys a dismal prognosis. In the United States there are currently no licensed therapies for treatment of IPF. The development of effective IPF clinical trials netwo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb35aa8edee1a65504b0e22ce4ab44a
https://doi.org/10.1016/j.ccm.2011.11.002
https://doi.org/10.1016/j.ccm.2011.11.002
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 4, Pp 426-432 (2008)
Cerebral vasospasm is one of the major complications of subarachnoid hemorrhage (SAH). The prevention and treatment of cerebral vasospasm thus plays a critical role in the management of SAH patients. However, the mechanism of cerebral vasospasm still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7df7d520d4eaec92422fccfd1da423
http://hdl.handle.net/2324/15567
http://hdl.handle.net/2324/15567
Autor:
Panagiota Zania, Christodoulos S. Flordellis, M. E. Papaconstantinou, Michael E. Maragoudakis, Nikos E. Tsopanoglou
Publikováno v:
American Journal of Physiology-Cell Physiology. 294:C1215-C1226
Thrombin has been reported to play a pivotal role in the initiation of angiogenesis by indirectly regulating and organizing a network of angiogenic molecules. In addition, it has been proposed that thrombin can directly activate endothelial cell prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dd9bf5f369e071bfa5944a6ba8cca4
https://doi.org/10.1152/ajpcell.00452.2007
https://doi.org/10.1152/ajpcell.00452.2007
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C1185-C1192
Subepithelial myofibroblast-derived prostaglandin E2(PGE2) regulates epithelial chloride secretion in the intestine. Thrombin is elevated in inflammatory conditions of the bowel. Therefore, we sought to determine a role for thrombin in regulating PGE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238b9e0e0ba7b442965f5a0a451bc5c1
https://doi.org/10.1152/ajpcell.00126.2002
https://doi.org/10.1152/ajpcell.00126.2002