Zobrazeno 1 - 10 of 17 pro vyhledávání: '"protein-tyrosine kinase (tyrosine kinase)"'
1
Activity-dependent conformational transitions of the insulin receptor–related receptor
Autor: Eduard V. Bocharov, Alexander N. Orsa, Alexander G. Petrenko, I. E. Deyev, Alexander S. Goryashchenko, Natalia V. Kuzmina, Ekaterina D. Mileshina, A. A. Mozhaev, Oleg V. Batishchev
Publikováno v: The Journal of Biological Chemistry
The insulin receptor (IR), insulin-like growth factor 1 receptor (IGF-1R), and insulin receptor-related receptor (IRR) form a mini family of predimerized receptor-like tyrosine kinases. IR and IGF-1R bind to their peptide agonists triggering metaboli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f854f8cc3042abb24bde19183c9956d
https://doi.org/10.1016/j.jbc.2021.100534
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2
Critical Role for an Acidic Amino Acid Region in Platelet Signaling by the HemITAM (Hemi-immunoreceptor Tyrosine-based Activation Motif) Containing Receptor CLEC-2 (C-type Lectin Receptor-2)
Autor: Anjali Pandey, Christopher A. O’Callaghan, Craig E. Hughes, Johannes A. Eble, Uma Sinha, Steve P. Watson
Publikováno v: The Journal of Biological Chemistry
Background: CLEC-2 signals through a cytosolic YXXL downstream of a triacidic amino acid sequence (hemITAM). Results: We show a critical role for the triacidic amino acid in phosphorylation of the cytosolic tyrosine and that CLEC-2 signals via Syk bu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51524dc823bb3e2bd3b4c7533fba45bd
https://doi.org/10.1074/jbc.m112.411462
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3
A New Pathway of CD5 Glycoprotein-mediated T Cell Inhibition Dependent on Inhibitory Phosphorylation of Fyn Kinase*
Autor: Marta I. Oliveira, Carine M. Gonçalves, Martina Bamberger, John R. James, Simon J. Davis, Ana Filipa L.O.M. Santos, Alexandre M. Carmo, Alexandra Moreira, Franscisco Lozano
Publikováno v: The Journal of Biological Chemistry
Triggering of the T cell receptor initiates a signaling cascade resulting in the activation of the T cell. These signals are integrated alongside those resulting from the triggering of other receptors whose function is to modulate the overall respons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0856d2270d532fa46514d76e81909ab9
http://europepmc.org/articles/PMC3162391
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4
Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia
Autor: Claudia Dafinger, Bernhard Schermer, Thomas Benzing, Roman U. Müller, Gerd Walz, Francesca Fabretti, Volker Burst, Andree Blaukat, Max C. Liebau, Martin Höhne, Matthias Hackl, Sibylle Zank, Hanswalter Zentgraf, Ingolf Schmedding, Benjamin Schairer, Sandra Habbig, Malte P. Bartram, Katja Höpker
Publikováno v: The Journal of Biological Chemistry
Nephronophthisis is the most common genetic cause of end-stage renal failure during childhood and adolescence. Genetic studies have identified disease-causing mutations in at least 11 different genes (NPHP1-11), but the function of the corresponding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27ba81e2c86e213b74ef919d5b7075f
https://doi.org/10.1074/jbc.m110.165464
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5
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway *
Autor: Virginie Thomé, Anne-Catherine Lhoumeau, Laurent Kodjabachian, Sébastien Martinez, Pierluigi Scerbo, Avais M. Daulat, Jean-Paul Borg, Marilyn Giordano
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (51), pp.30562-30572. ⟨10.1074/jbc.M115.697615⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (51), pp.30562-72. ⟨10.1074/jbc.M115.697615⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, 2015, 290 (51), pp.30562-30572. ⟨10.1074/jbc.M115.697615⟩
Background: The planar cell polarity pathway plays important roles in morphogenetic processes. Results: PTK7 and ROR2 form a heterodimeric complex and bind to WNT5A, promoting JNK phosphorylation and regulating expression of paraxial protocadherin. C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ec7db2813ce4a0ab1d1c2f1a212282
https://hal.archives-ouvertes.fr/hal-01306990
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6
Akademický článek
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7
Akademický článek
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8
Akademický článek
Activity-dependent conformational transitions of the insulin receptor-related receptor.
Autor: Batishchev OV; A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russia. Electronic address: olegbati@gmail.com., Kuzmina NV; A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russia., Mozhaev AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; Shubnikov Institute of Crystallography of Federal Scientific Research Centre 'Crystallography and Photonics', Russian Academy of Sciences, Moscow, Russia., Goryashchenko AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Mileshina ED; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Orsa AN; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Bocharov EV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia; Moscow Institute of Physics and Technology, Dolgoprudniy, Moscow Region, Russia., Deyev IE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Petrenko AG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100534. Date of Electronic Publication: 2021 Mar 11.
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9
Akademický článek
The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway.
Autor: Martinez S; From the CRCM, Cell Polarity, Cell Signaling, and Cancer 'Equipe Labellisée Ligue Contre le Cancer', INSERM, U1068, 13009 Marseille, France, the Institut Paoli-Calmettes, 13009 Marseille, France, the Aix-Marseille Université, 13284 Marseille, France, the CNRS, UMR7258, 13009 Marseille, France, and., Scerbo P; the Institut de Biologie du Développement de Marseille, Aix-Marseille Université, CNRS, 13288 Marseille, France., Giordano M; From the CRCM, Cell Polarity, Cell Signaling, and Cancer 'Equipe Labellisée Ligue Contre le Cancer', INSERM, U1068, 13009 Marseille, France, the Institut Paoli-Calmettes, 13009 Marseille, France, the Aix-Marseille Université, 13284 Marseille, France, the CNRS, UMR7258, 13009 Marseille, France, and., Daulat AM; From the CRCM, Cell Polarity, Cell Signaling, and Cancer 'Equipe Labellisée Ligue Contre le Cancer', INSERM, U1068, 13009 Marseille, France, the Institut Paoli-Calmettes, 13009 Marseille, France, the Aix-Marseille Université, 13284 Marseille, France, the CNRS, UMR7258, 13009 Marseille, France, and., Lhoumeau AC; From the CRCM, Cell Polarity, Cell Signaling, and Cancer 'Equipe Labellisée Ligue Contre le Cancer', INSERM, U1068, 13009 Marseille, France, the Institut Paoli-Calmettes, 13009 Marseille, France, the Aix-Marseille Université, 13284 Marseille, France, the CNRS, UMR7258, 13009 Marseille, France, and., Thomé V; the Institut de Biologie du Développement de Marseille, Aix-Marseille Université, CNRS, 13288 Marseille, France., Kodjabachian L; the Institut de Biologie du Développement de Marseille, Aix-Marseille Université, CNRS, 13288 Marseille, France., Borg JP; From the CRCM, Cell Polarity, Cell Signaling, and Cancer 'Equipe Labellisée Ligue Contre le Cancer', INSERM, U1068, 13009 Marseille, France, the Institut Paoli-Calmettes, 13009 Marseille, France, the Aix-Marseille Université, 13284 Marseille, France, the CNRS, UMR7258, 13009 Marseille, France, and jean-paul.borg@inserm.fr.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2015 Dec 18; Vol. 290 (51), pp. 30562-72. Date of Electronic Publication: 2015 Oct 23.
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10
Akademický článek
Different epidermal growth factor (EGF) receptor ligands show distinct kinetics and biased or partial agonism for homodimer and heterodimer formation.
Autor: Macdonald-Obermann JL; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110., Pike LJ; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110. Electronic address: pike@biochem.wustl.edu.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2014 Sep 19; Vol. 289 (38), pp. 26178-26188. Date of Electronic Publication: 2014 Aug 01.
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