Zobrazeno 1 - 10
of 27 289
pro vyhledávání: '"protein-phosphorylation"'
Publikováno v:
Xibei zhiwu xuebao, Vol 44, Iss 10, Pp 1567-1576 (2024)
Abstract [Objective] Using phosphoproteomics, expression patterns of the phosphorylated proteins were analyzed with tetraploid Citrus wilsonii leaves under drought stress, aiming to reveal the mechanism of tetraploid C. wilsonii in response to drou
Externí odkaz:
https://doaj.org/article/4926b7174f3d4d1da2770aa80dad7ac8
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39217- (2024)
Alzheimer's disease (AD) is a severe neurodegenerative disorder characterized by the accumulation of β-amyloid (Aβ) plaques and tau phosphorylation-induced neurofibrillary tangles. This review comprehensively summarizes AD pathogenesis and related
Externí odkaz:
https://doaj.org/article/fc7efd181b3f4dce861376b3ba715058
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Background The glycolytic enzyme alpha-enolase is a known biomarker of many cancers and involved in tumorigenic functions unrelated to its key role in glycolysis. Here, we show that expression of alpha-enolase correlates with subcellular loc
Externí odkaz:
https://doaj.org/article/ebc6ef5325644d92b45ceca6d5fe45d8
Publikováno v:
Genes and Diseases, Vol 12, Iss 2, Pp 101179- (2025)
Family with sequence similarity 20 C (FAM20C) is a Golgi protein kinase that phosphorylates the serine residue in the S-x-E/pS motif of target proteins. FAM20C phosphorylates most secreted proteins, which play important roles in multiple biological p
Externí odkaz:
https://doaj.org/article/bc04c2a50863445f8dbe963415bd3ed9
Akademický článek
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Autor:
Ruiming Zhang, Xinyu Liu, Jiayun Xu, Chen Chen, Zhaoxuan Tang, Chengtong Wu, Xinyue Li, Lei Su, Muxing Liu, Leiyun Yang, Gang Li, Haifeng Zhang, Ping Wang, Zhengguang Zhang
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Regulator of G-protein signaling (RGS) proteins exhibit GTPase-accelerating protein activities to govern G-protein function. In the rice blast fungus Magnaporthe oryzae, there is a family of at least eight RGS and RGS-like proteins (MoRgs1 t
Externí odkaz:
https://doaj.org/article/2a3e10a964bc4a4fa46c134d3a2204d9
Autor:
Adrienn Márton, Katalin Beáta Veres, Ferenc Erdődi, Miklós Udvardy, Árpád Illés, László Rejtő
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Signaling pathways of Retinoblastoma (Rb) protein, Akt-kinase, and Erk-kinase (extracellular signal-regulated kinase) have an important role in the pathogenesis of acute myeloid leukemia. Constitutive activation of these proteins by phosphorylation c
Externí odkaz:
https://doaj.org/article/34c96f35a12d4e5eba81658072e06f83
Autor:
Yu Wei, Dian Zhang, He Shi, Husun Qian, Hongling Chen, Qian Zeng, Fangfang Jin, Yan Ye, Zuli Ou, Minkang Guo, Bianqin Guo, Tingmei Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101041- (2024)
Pyruvate dehydrogenase kinase 1 (PDK1) phosphorylates the pyruvate dehydrogenase complex, which inhibits its activity. Inhibiting pyruvate dehydrogenase complex inhibits the tricarboxylic acid cycle and the reprogramming of tumor cell metabolism to g
Externí odkaz:
https://doaj.org/article/50920ea8a3fb4725b15b4adbeb683a89
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Cyclic adenosine 3’, 5’ monophosphate (cAMP)-dependent Protein Kinase A (PKA) is a multi-functional serine/threonine kinase that regulates a wide variety of physiological processes including gene transcription, metabolism, and synaptic p
Externí odkaz:
https://doaj.org/article/5f57dffc5eb5471c8e55ce70b1390b9a
Publikováno v:
Shipin Kexue, Vol 45, Iss 2, Pp 17-23 (2024)
Postmortem mutton longissimus dorsi was minced and treated separately with phosphatase inhibitor, kinase inhibitor, S-nitrosoglutathione and nitric oxide synthase (NOS) inhibitor to control the degrees of phosphorylation and S-nitrosylation. The effe
Externí odkaz:
https://doaj.org/article/2cda2697bdf44bfe93d740a1163eb0cd