Zobrazeno 1 - 10
of 145
pro vyhledávání: '"protein-peptide docking"'
Publikováno v:
Journal of Pure and Applied Microbiology, Vol 18, Iss 3, Pp 1674-1683 (2024)
Targeting the class A Beta lactamases Omega loop is an ideal way to combat drug resistance because of its significant role in the catalytic activity and deacylation process inhibition. Therefore, the molecular docking approach with computerized pepti
Externí odkaz:
https://doaj.org/article/f32c632b4a3945ecaa8450e07f1bb150
Autor:
Manisha Mandal, Shyamapada Mandal
Publikováno v:
Chemical Physics Impact, Vol 8, Iss , Pp 100401- (2024)
The antimicrobial peptides (AMPs) have been regarded as the next generation antibiotics. This study aimed to explore the AMP inhibitors of β-lactamase enzyme employing computational biology methods. Protein-peptide docking of Acinetobacter baumannii
Externí odkaz:
https://doaj.org/article/8f6f1a890a724cb1a3e552933aed1285
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Aggregation of β-amyloid (Aβ) peptide is one of the hallmarks of Alzheimer’s disease (AD) which results in chronic and progressive neurodegeneration of the brain. A recent study by our group have shown the ability of cyclic disulfide-rich peptide
Externí odkaz:
https://doaj.org/article/deb412d2c9304a518229e14d1ac66b86
Akademický článek
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Autor:
Nail Besli, Guven Yenmis
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 4, Pp 1262-1272 (2020)
Alzheimer's disease is a major neurodegenerative illness whose prevalence is increasing worldwide but the molecular mechanism remains unclear. There is some scientific evidence that the molecular complexity of Alzheimer's pathophysiology is associate
Externí odkaz:
https://doaj.org/article/612e0918eef34d7788531b488ae9d054
Publikováno v:
Informatics in Medicine Unlocked, Vol 35, Iss , Pp 101128- (2022)
Matrix metalloproteinases-1 is recognized as a potential target of tumors and cancer for their role in breaking down collagen and extracellular matrix proteins. Our study screened 51 peptides against MMP-1 to find potent inhibitors for preventing bre
Externí odkaz:
https://doaj.org/article/72e81562ce71472398ba4435bea356da
Autor:
Atilio Reyes Romero, Katarzyna Kubica, Radoslaw Kitel, Ismael Rodríguez, Katarzyna Magiera-Mularz, Alexander Dömling, Tad A. Holak, Ewa Surmiak
Publikováno v:
Molecules, Vol 27, Iss 23, p 8282 (2022)
By binding to the spliceosomal protein Snu66, the human ubiquitin-like protein Hub1 is a modulator of the spliceosome performance and facilitates alternative splicing. Small molecules that bind to Hub1 would be of interest to study the protein-protei
Externí odkaz:
https://doaj.org/article/4d220aacd0f442a4af06fca7242ed41d
Autor:
Didier Devaurs, Dinler A Antunes, Sarah Hall-Swan, Nicole Mitchell, Mark Moll, Gregory Lizée, Lydia E Kavraki
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Docking large ligands, and especially peptides, to protein receptors is still considered a challenge in computational structural biology. Besides the issue of accurately scoring the binding modes of a protein-ligand complex produc
Externí odkaz:
https://doaj.org/article/31d75520ccd24ca6b48f5ab28ef494ca