Zobrazeno 1 - 10
of 260
pro vyhledávání: '"protein transduction domains"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4088 (2024)
One of the bottlenecks to bringing new therapies to the clinic has been a lack of vectors for delivering novel therapeutics in a targeted manner. Cell penetrating peptides (CPPs) have received a lot of attention and have been the subject of numerous
Externí odkaz:
https://doaj.org/article/921325dae9b1445daa99f0ceea2b7a48
Autor:
Daniella Sahagun, Maliha Zahid
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1690 (2023)
Despite significant strides in prevention, diagnosis, and treatment, cardiovascular diseases remain the number one cause of mortality in the United States, with rates climbing at an alarming rate in the developing world. Targeted delivery of therapeu
Externí odkaz:
https://doaj.org/article/819ed105b4e845f6a481b83d824cbd1a
Autor:
Daniel P. Morris, Lucy C. Snipes, Stephanie A. Hill, Michael M. Woods, Maria M. Mbugua, Lydia R. Wade, Jonathan L. McMurry
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a62ad986de8b4c07828a543fcc3d4e9c
Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0d2cdac0e91f44b99bf62424f7b09545
Autor:
Daniel P. Morris, Lucy C. Snipes, Stephanie A. Hill, Michael M. Woods, Maria M. Mbugua, Lydia R. Wade, Jonathan L. McMurry
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cell penetrating peptides (CPPs) are a promising technology for therapeutic delivery of macromolecular cargos. CPPs have generally used covalent linkages to cargo, ensuring a common fate as one molecule. Conversely, our CPP-adaptor, TAT-CaM, noncoval
Externí odkaz:
https://doaj.org/article/6758b87d0f02454bac4de258f77de1a3
Autor:
Behnam Hasannejad-Asl, Farkhondeh Pooresmaeil, Shahla Takamoli, Mehran Dabiri, Azam Bolhassani
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
One of the main obstacles to most medication administrations (such as the vaccine constructs) is the cellular membrane’s inadequate permeability, which reduces their efficiency. Cell-penetrating peptides (CPPs) or protein transduction domains (PTDs
Externí odkaz:
https://doaj.org/article/506dfa3c7f75478499423f69673cb3d3
Akademický článek
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Publikováno v:
Biomolecular Concepts, Vol 8, Iss 3-4, Pp 131-141 (2017)
Cell-penetrating peptides (CPPs) have long held great promise for the manipulation of living cells for therapeutic and research purposes. They allow a wide array of biomolecules from large, oligomeric proteins to nucleic acids and small molecules to
Externí odkaz:
https://doaj.org/article/e890256e99584114a9346158848d299d
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 890 (2021)
Since their identification over twenty-five years ago, the plethora of cell-penetrating peptides (CPP) and their applications has skyrocketed. These 5 to 30 amino acid in length peptides have the unique property of breaching the cell membrane barrier
Externí odkaz:
https://doaj.org/article/32f2d4b1d0a2426f8caa4069d5221a35
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 8, Iss C, Pp 51-60 (2016)
Propionic acidemia (PA) is a life-threatening disease caused by the deficiency of a mitochondrial biotin-dependent enzyme known as propionyl coenzyme-A carboxylase (PCC). This enzyme is responsible for degrading the metabolic intermediate, propionyl
Externí odkaz:
https://doaj.org/article/1744eef3ac67426d8bb113eb2aedbb41