Zobrazeno 1 - 10
of 662
pro vyhledávání: '"protein therapy"'
Autor:
Shiying Zhao, Alexander V. Tschulakow, Subha S. Karthikeyan, Kun Wang, Stefan Kochanek, Ulrich Schraermeyer, Sylvie Julien‐Schraermeyer
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 9, Pp 311-326 (2024)
Abstract Retinopathy of prematurity (ROP) is a severe retinal disease in premature infants characterized by pathological neovascularization, obliteration of retinal vessels and increased vessel tortuosity. Currently, there are no completely satisfact
Externí odkaz:
https://doaj.org/article/2a9b5bffc3bc4994b1a7b2044bb000bb
Autor:
Jung Hwan Park, Min Jea Shin, Gi Soo Youn, Hyeon Ji Yeo, Eun Ji Yeo, Hyun Jung Kwon, Lee Re Lee, Na Yeon Kim, Su Yeon Kwon, Su Min Kim, Yong-Jun Cho, Sung Ho Lee, Hyo Young Jung, Dae Won Kim, Won Sik Eum, Soo Young Choi
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2352 (2024)
Background: The peptidyl-prolyl isomerase (PIN1) plays a vital role in cellular processes, including intracellular signaling and apoptosis. While oxidative stress is considered one of the primary mechanisms of pathogenesis in brain ischemic injury, t
Externí odkaz:
https://doaj.org/article/23e43d1e220142889331a568b65d2956
Autor:
Ariel A. Di Nardo, Alain Prochiantz
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Cell signaling based on homeoprotein transfer is a pathway with developmental and physiological functions. For a few transcription factors of this family, primarily ENGRAILED1, ENGRAILED2 and OTX2, their physiological functions have led to therapeuti
Externí odkaz:
https://doaj.org/article/f1bf5ddb1fe145c2bbd135a0be3e97a0
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23488- (2024)
Background: Bain ischemia is a disease that occurs for various reasons, induces reactive oxygen species (ROS), and causes fatal damage to the nervous system. Protective effect of HPCA on ischemic injury has not been extensively studied despite its si
Externí odkaz:
https://doaj.org/article/874e41eb29b449a4a95e2e8c5627840d
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 49, Iss 3, Pp 176-181 (2022)
With the continuous progress of tumor treatment methods in recent years, more and more emerging antitumor drugs have been approved to market and put into clinical use. In addition, some treatments that are in clinical trials such as gene therapy are
Externí odkaz:
https://doaj.org/article/713b88e294d946419c5688b89cb76fc7
Autor:
Androulla N. Miliotou, Ioannis S. Pappas, George Spyroulias, Efthimia Vlachaki, Asterios S. Tsiftsoglou, Ioannis S. Vizirianakis, Lefkothea C. Papadopoulou
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 694-710 (2021)
The potential clinical applications of the powerful in vitro-transcribed (IVT)-mRNAs, to restore defective protein functions, strongly depend on their successful intracellular delivery and transient translation through the development of safe and eff
Externí odkaz:
https://doaj.org/article/afd153d731564b958ed59676a877f44c
Autor:
Ming Zhao, Jing Wang, Jinxin Zhang, Jingman Huang, Liang Luo, Yunshu Yang, Kuo Shen, Tian Jiao, Yanhui Jia, Weilong Lian, Jin Li, Yunchuan Wang, Qin Lian, Dahai Hu
Publikováno v:
Materials Today Bio, Vol 16, Iss , Pp 100334- (2022)
In-situ three-dimensional (3D) bioprinting has been emerging as a promising technology designed to rapidly seal cutaneous defects according to their contour. Improvements in the formulations of multi-component bioink are needed to support cytocompati
Externí odkaz:
https://doaj.org/article/9e44c5f346f74564a03223a9c14ca02a