Zobrazeno 1 - 10
of 5 713
pro vyhledávání: '"protein sequence"'
Autor:
Gu, Xun, author
Publikováno v:
Statistical Analysis of Molecular and Genomic Evolution, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780198816515.003.0005
Autor:
Gu, Xun, author
Publikováno v:
Statistical Analysis of Molecular and Genomic Evolution, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780198816515.003.0001
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2648-2660 (2024)
Therapeutic antibodies are an important class of biopharmaceuticals. With the rapid development of deep learning methods and the increasing amount of antibody data, antibody generative models have made great progress recently. They aim to solve the a
Externí odkaz:
https://doaj.org/article/78ec974f94564acbad066965e6836843
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2637-2647 (2024)
Molecular phylogenetic research has relied on the analysis of the coding sequences by genes or of the amino acid sequences by the encoded proteins. Enumerating the numbers of mismatches, being indicators of mutation, has been central to pertinent alg
Externí odkaz:
https://doaj.org/article/f417692da0974ff4b31e1e9584e8dcab
Publikováno v:
hLife, Vol 2, Iss 11, Pp 576-591 (2024)
Various precise gene editing techniques at the DNA/RNA level, driven by clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) technology, have gained significant prominence. Yet, research on targeted pro
Externí odkaz:
https://doaj.org/article/8d24ef6e0b5d4e57a9c289ab18cfe041
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background The maximal sensitivity for local pairwise alignment makes the Smith-Waterman algorithm a popular choice for protein sequence database search. However, its quadratic time complexity makes it compute-intensive. Unfortunately, curre
Externí odkaz:
https://doaj.org/article/d102e0370e68428395257f3aa5fc874a
Autor:
Umesh Kumar Lilhore, Sarita Simiaya, Musaed Alhussein, Neetu Faujdar, Surjeet Dalal, Khursheed Aurangzeb
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Efforts to enhance the accuracy of protein sequence classification are of utmost importance in driving forward biological analyses and facilitating significant medical advancements. This study presents a cutting-edge model called ProtICNN-Bi
Externí odkaz:
https://doaj.org/article/5c0bb4ee34824bf2a28f965df7882e64
Publikováno v:
Bioresources and Bioprocessing, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Gelatin is a product obtained through partial hydrolysis and thermal denaturation of collagen, belonging to natural biopeptides. With irreplaceable biological functions in the field of biomedical science and tissue engineering, it has been w
Externí odkaz:
https://doaj.org/article/d926ec7e89d64a1f8cd720175b3e76a7
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36041- (2024)
Protein solubility prediction is useful for the careful selection of highly effective candidate proteins for drug development. In recombinant proteins synthesis, solubility prediction is valuable for optimizing key protein characteristics, including
Externí odkaz:
https://doaj.org/article/340d63b8e2084ba8a4b934bbd12eb12d
Autor:
Benjamin Giovanni Iovino, Yuzhen Ye
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Purpose Despite the many progresses with alignment algorithms, aligning divergent protein sequences with less than 20–35% pairwise identity (so called "twilight zone") remains a difficult problem. Many alignment algorithms have been using
Externí odkaz:
https://doaj.org/article/0924ae79c6104d58a44e5fb015f4ef49