Zobrazeno 1 - 10
of 52
pro vyhledávání: '"protein quality control (PQC)"'
Autor:
Stefano Magnati, Enrico Bracco
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 158-167 (2024)
In the last few decades, the traditional paradigm of teleonomy, in which the amino acid sequence of a protein is tightly associated with its structure and, in turn, with its function, has been partially undermined. The idea of a protein as a two-stat
Externí odkaz:
https://doaj.org/article/0b087316a3174ade84b0ecdb5a46eb10
Publikováno v:
In BBA - Molecular Cell Research December 2022 1869(12)
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The function, stability, and turnover of plasma membrane (PM) proteins are crucial for cellular homeostasis. Compared to soluble proteins, quality control of plasma membrane proteins is extremely challenging. Failure to meet the high quality control
Externí odkaz:
https://doaj.org/article/a06e9fc1ad6e487b8697084fff7e13e2
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Purpose of Review: This review summarizes the current evidence for the involvement of proteotoxicity and protein quality control systems defects in diseases of the central nervous and cardiovascular systems. Specifically, it presents the commonalitie
Externí odkaz:
https://doaj.org/article/03e5714c1e6042069ba48198fb1530ea
Kniha
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Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Heart failure is a serious comorbidity and the most common cause of mortality in diabetes patients. Diabetic cardiomyopathy (DCM) features impaired cellular structure and function, culminating in heart failure; however, there is a dearth of specific
Externí odkaz:
https://doaj.org/article/dd606e8465804e2cb55d41fc14282819
Autor:
Ofri Karmon, Shay Ben Aroya
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2020)
Misfolded proteins and insoluble aggregates are continuously produced in the cell and can result in severe stress that threatens cellular fitness and viability if not managed effectively. Accordingly, organisms have evolved several protective protein
Externí odkaz:
https://doaj.org/article/a3427c9587e64590a9ae43c3e1f375a9
Autor:
Delligatti, Christine E., Kirk, Jonathan A. ⁎
Publikováno v:
In Vitamins & Hormones 2024 125:47-88
