Zobrazeno 1 - 10
of 1 827
pro vyhledávání: '"protein families"'
Autor:
Lovro Trgovec-Greif, Hans-Jörg Hellinger, Jean Mainguy, Alexander Pfundner, Dmitrij Frishman, Michael Kiening, Nicole Suzanne Webster, Patrick William Laffy, Michael Feichtinger, Thomas Rattei
Publikováno v:
Viruses, Vol 16, Iss 8, p 1191 (2024)
Computational models of homologous protein groups are essential in sequence bioinformatics. Due to the diversity and rapid evolution of viruses, the grouping of protein sequences from virus genomes is particularly challenging. The low sequence simila
Externí odkaz:
https://doaj.org/article/a644012610f94292b2394d55a52903d6
Autor:
Megan E. Garber, Vered Frank, Alexey E. Kazakov, Matthew R. Incha, Alberto A. Nava, Hanqiao Zhang, Luis E. Valencia, Jay D. Keasling, Lara Rajeev, Aindrila Mukhopadhyay
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThis report presents multi-genome evidence that REC protein family expansion occurs when the emergence of new pathways gives rise to functional discordance. Specificity between residues in REC domain containing response regulators with paired
Externí odkaz:
https://doaj.org/article/1b5e31e2aab640b78a76252a4e5a2252
Autor:
Gabriel Montenegro de Campos, Eleonora Cella, Simone Kashima, Luiz Carlos Júnior Alcântara, Sandra Coccuzzo Sampaio, Maria Carolina Elias, Marta Giovanetti, Svetoslav Nanev Slavov
Publikováno v:
Viruses, Vol 16, Iss 2, p 171 (2024)
Nipah virus (NiV), a biosafety level 4 agent, was first identified in human clinical cases during an outbreak in 1998 in Malaysia and Singapore. While flying foxes are the primary host and viral vector, the infection is associated with a severe clini
Externí odkaz:
https://doaj.org/article/944f26d22e814ef28bd3823f707dbc30
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background The human body is inhabited by a diverse community of commensal non-pathogenic bacteria, many of which are essential for our health. By contrast, pathogenic bacteria have the ability to invade their hosts and cause a disease. Char
Externí odkaz:
https://doaj.org/article/0cee292138a84f53abcb7b73616a3c85
Publikováno v:
eLife, Vol 12 (2023)
Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function. They thus open the possibility for generat
Externí odkaz:
https://doaj.org/article/e70f27eb796c4ed0a4fedfe5369ddcb7
Publikováno v:
PeerJ, Vol 11, p e14779 (2023)
A major challenge for clustering algorithms is to balance the trade-off between homogeneity, i.e., the degree to which an individual cluster includes only related sequences, and completeness, the degree to which related sequences are broken up into m
Externí odkaz:
https://doaj.org/article/964e4597d0f8411aaef97cf7919a6a94
Akademický článek
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Akademický článek
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Autor:
Mariana Tarallo, Rebecca L. McDougal, Zhiyuan Chen, Yan Wang, Rosie E. Bradshaw, Carl H. Mesarich
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Dothistroma septosporum (Ds) and Fulvia fulva (Ff; previously called Cladosporium fulvum) are two closely related Dothideomycete fungal species that cause Dothistroma needle blight in pine and leaf mold in tomato, respectively. During host colonizati
Externí odkaz:
https://doaj.org/article/fea743f4451e43908aaa6d3e8a2941b7
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-28 (2021)
Abstract Background The identification of protein families is of outstanding practical importance for in silico protein annotation and is at the basis of several bioinformatic resources. Pfam is possibly the most well known protein family database, b
Externí odkaz:
https://doaj.org/article/4f45ff1211ed4534b6cfa792428876d4