Symmetric versus Asymmetric Features of Homologous Homodimeric Amine Oxidases: When Water and Cavities Make the Difference

Autor: Eleonora Nicolai, Velia Minicozzi, Luisa Di Paola, Rosaria Medda, Francesca Pintus, Giampiero Mei, Almerinda Di Venere

Publikováno v: Symmetry, Vol 14, Iss 3, p 522 (2022)

Symmetry is an intrinsic property of homo-oligomers. Amine oxidases are multidomain homodimeric enzymes that contain one catalytic site per subunit, and that share a high homology degree. In this paper, we investigated, by fluorescence spectroscopy m

Externí odkaz: https://doaj.org/article/0847187a054145df8b2301c10c5c5fab

Asymmetric expression of proteins in the granules of the placentomal Binucleate cells in Giraffa camelopardalis†

Autor: Wooding, FBP, Forhead, AJ, Wilsher, S, Allen, WR, Roberts, RM, Green, JA, Beckers, JF, Melo Sousa, N, Charpigny, G

Publikováno v: Biology of reproduction. 106(4)

Mature granulated trophoblast binucleate cells (BNC) have been found in all ruminant placentas examined histologically so far. BNC are normally fairly evenly distributed throughout the fetal villus and all their granules contain a similar variety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1707a2cc6fee00743899e468dd89d1ad
https://pubmed.ncbi.nlm.nih.gov/35040958

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Characterization of HIV-2 Protease Structure by Studying Its Asymmetry at the Different Levels of Protein Description

Autor: Ollitrault, Guillaume, Fartek, Sandrine, Descamps, Diane, Camproux, Anne-Claude, Visseaux, Benoît, Regad, Leslie

Publikováno v: Symmetry, Vol 10, Iss 11, p 644 (2018)
Symmetry
Volume 10
Issue 11

HIV-2 protease (PR2) is a homodimer, which is an important target in the treatment of the HIV-2 infection. In this study, we developed an in silico protocol to analyze and characterize the asymmetry of the unbound PR2 structure using three levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f953015e79ac2932b73e629a8d6ffb46
https://www.mdpi.com/2073-8994/10/11/644

Membrane bending by protein crowding is affected by protein lateral confinement

Autor: Alenka Čopič, Jure Derganc

Publikováno v: BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, 1858 (6), pp.1152-9. ⟨10.1016/j.bbamem.2016.03.009⟩
Biochimica et Biophysica Acta (BBA)-Biomembranes

International audience; Crowding of asymmetrically-distributed membrane proteins has been recently recognized as an important factor in remodeling of biological membranes, for example during transport vesicle formation. In this paper, we theoreticall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278ff941ed44ca65c6ddc83578132666
https://pubmed.ncbi.nlm.nih.gov/26969088