Zobrazeno 1 - 10
of 1 688
pro vyhledávání: '"protein arginine methyltransferase"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 8, Pp 999-1010 (2024)
Objective·To examine the expression level of protein arginine methyltransferase 6 (PRMT6) in breast carcinoma tissues and to assess its impact on the proliferative and migratory behaviors of breast cancer cells.Methods·The PRMT6 transcriptome seque
Externí odkaz:
https://doaj.org/article/3648dfc5357e46a98118db56973d8b74
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 11, Pp 15-27 (2024)
Jia Yan,1– 3,* Ke xin Li,2,* Lei Yu,2 Heng ye Yuan,2 Zhi min Zhao,2 Jing Lin,2,4 Chang Shan Wang2 1School of Basic Medicine, Inner Mongolia Medical University, Hohhot, Inner Mongolia, People’s Republic of China; 2College of Life Science,
Externí odkaz:
https://doaj.org/article/78bf4f569eb04b76a385de010118f023
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Medial vascular calcification is commonly identified in chronic kidney disease (CKD) patients and seriously affects the health and life quality of patients. This study aimed to investigate the effects of protein arginine methyltra
Externí odkaz:
https://doaj.org/article/5ef6ce4456e940eb9ddbfb7b60052072
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 6, Pp 590-602 (2023)
This study aimed to evaluate the therapeutic potential of inhibiting protein arginine methyltransferase 5 (PRMT5) in cisplatin-induced hearing loss. The effects of PRMT5 inhibition on cisplatin-induced auditory injury were determined using immunohist
Externí odkaz:
https://doaj.org/article/0ff86071a5b3497cba2f3fbf2e8bd517
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundInduced regulatory T cells (iTregs) are a heterogeneous population of immunosuppressive T cells with therapeutic potential. Treg cells show a range of plasticity and can acquire T effector-like capacities, as is the case for T helper 1 (Th1
Externí odkaz:
https://doaj.org/article/f3118f8df2914968bdb66c696b33ddb9
Publikováno v:
Zhongguo aizheng zazhi, Vol 33, Iss 5, Pp 437-444 (2023)
Background and purpose: Bladder cancer is one of the common tumor of the urinary system. The protein arginine methyltransferase 7 (PRMT7) has been reported in gastrointestinal tumors, but its biological role and mechanism in bladder cancer are still
Externí odkaz:
https://doaj.org/article/a91b2949db234b4097ab2aa95229b2b0
Autor:
Nayeong Yuk, Hye Jin Jung
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2950 (2024)
Glioblastoma stem cells (GSCs) play a pivotal role in the initiation, progression, resistance to treatment, and relapse of glioblastoma multiforme (GBM). Thus, identifying potential therapeutic targets and drugs that interfere with the growth of GSCs
Externí odkaz:
https://doaj.org/article/453a8b6aa4f048a8af8ccb3edffd29d5
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115456- (2023)
Tumor metastasis is the leading cause of mortality among advanced cancer patients. Understanding its mechanisms and treatment strategies is vital for clinical application. Arginine methylation, a post-translational modification catalyzed by protein a
Externí odkaz:
https://doaj.org/article/5c26a8b5ec924d6abd4e5bf5f73f9a65
Publikováno v:
Chinese Journal of Physiology, Vol 66, Iss 1, Pp 43-51 (2023)
Prostate cancer (PCa) is one of the leading causes of cancer-related death in males worldwide and exploring more reliable biomarkers for PCa is essential for the diagnosis and therapeutics for the disease. Although the functions of miR-141-3p and Alk
Externí odkaz:
https://doaj.org/article/336269bae2024efeb1842a7b00971bb3
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Protein arginine methyltransferases (PRMTs) regulate protein biological activity by modulating arginine methylation in cancer and are increasingly recognized as potential drug targets. Inhibitors targeting PRMTs are currently in t
Externí odkaz:
https://doaj.org/article/649aac8a497d456186ed234f7d1bce6c